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Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

Machine Learning · Computer Science 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

Long-tailed distributions in class-imbalanced data present a fundamental challenge for deep learning models, which tend to be biased toward majority classes. While recent methods for long-tailed recognition have mitigated this issue, they…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Heegeon Yoon , Heeyoung Kim

Multimodal Magnetic Resonance Imaging (MRI) provides essential complementary information for analyzing brain tumor subregions. While methods using four common MRI modalities for automatic segmentation have shown success, they often face…

Image and Video Processing · Electrical Eng. & Systems 2024-11-14 Runze Cheng , Zhongao Sun , Ye Zhang , Chun Li

In real medical data, training samples typically show long-tailed distributions with multiple labels. Class distribution of the medical data has a long-tailed shape, in which the incidence of different diseases is quite varied, and at the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Wongi Park , Inhyuk Park , Sungeun Kim , Jongbin Ryu

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents an even more difficult scenario. To cope with this challenge,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-16 Tianyi Liu , Zhaorui Tan , Haochuan Jiang , Xi Yang , Kaizhu Huang

In real-world scenarios, where knowledge distributions exhibit long-tail. Humans manage to master knowledge uniformly across imbalanced distributions, a feat attributed to their diligent practices of reviewing, summarizing, and correcting…

Computer Vision and Pattern Recognition · Computer Science 2024-09-16 Qihao Zhao , Yalun Dai , Shen Lin , Wei Hu , Fan Zhang , Jun Liu

Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

Radiologists must utilize multiple modal images for tumor segmentation and diagnosis due to the limitations of medical imaging and the diversity of tumor signals. This leads to the development of multimodal learning in segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Chuyun Shen , Wenhao Li , Haoqing Chen , Xiaoling Wang , Fengping Zhu , Yuxin Li , Xiangfeng Wang , Bo Jin

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

Machine Learning · Computer Science 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Combining multiple modalities carrying complementary information through multimodal learning (MML) has shown considerable benefits for diagnosing multiple pathologies. However, the robustness of multimodal models to missing modalities is…

Machine Learning · Computer Science 2024-07-31 Hava Chaptoukaev , Vincenzo Marcianó , Francesco Galati , Maria A. Zuluaga

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

Multimodal learning is susceptible to modality missing, which poses a major obstacle for its practical applications and, thus, invigorates increasing research interest. In this paper, we investigate two challenging problems: 1) when…

Machine Learning · Computer Science 2023-12-19 Jun Sun , Xinxin Zhang , Shoukang Han , Yu-ping Ruan , Taihao Li

An active challenge in developing multimodal machine learning (ML) models for healthcare is handling missing modalities during training and deployment. As clinical datasets are inherently temporal and sparse in terms of modality presence,…

Machine Learning · Computer Science 2026-05-08 Andrew Wang , Ellie Pavlick , Ritambhara Singh

Medical multimodal representation learning aims to integrate heterogeneous clinical data into unified patient representations to support predictive modeling, which remains an essential yet challenging task in the medical data mining…

Machine Learning · Computer Science 2025-09-09 Xiaoguang Zhu , Lianlong Sun , Yang Liu , Pengyi Jiang , Uma Srivatsa , Nipavan Chiamvimonvat , Vladimir Filkov

Multimodal fusion leverages information across modalities to learn better feature representations with the goal of improving performance in fusion-based tasks. However, multimodal datasets, especially in medical settings, are typically…

Machine Learning · Computer Science 2025-02-05 Alejandro Guerra-Manzanares , Farah E. Shamout

Purpose High dimensional, multimodal data can nowadays be analyzed by huge deep neural networks with little effort. Several fusion methods for bringing together different modalities have been developed. Given the prevalence of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Christian Gapp , Elias Tappeiner , Martin Welk , Karl Fritscher , Elke Ruth Gizewski , Rainer Schubert

While humans excel at continual learning (CL), deep neural networks (DNNs) exhibit catastrophic forgetting. A salient feature of the brain that allows effective CL is that it utilizes multiple modalities for learning and inference, which is…

Machine Learning · Computer Science 2024-05-07 Fahad Sarfraz , Bahram Zonooz , Elahe Arani

Multimodal Re-Identification (ReID) is a popular retrieval task that aims to re-identify objects across diverse data streams, prompting many researchers to integrate multiple modalities into a unified representation. While such fusion…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Jennifer Crawford , Haoli Yin , Luke McDermott , Daniel Cummings

Long-tailed data is a special type of multi-class imbalanced data with a very large amount of minority/tail classes that have a very significant combined influence. Long-tailed learning aims to build high-performance models on datasets with…

Machine Learning · Computer Science 2024-08-02 Chongsheng Zhang , George Almpanidis , Gaojuan Fan , Binquan Deng , Yanbo Zhang , Ji Liu , Aouaidjia Kamel , Paolo Soda , João Gama
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