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Phylogenomics is a new field which applies to tools in phylogenetics to genome data. Due to a new technology and increasing amount of data, we face new challenges to analyze them over a space of phylogenetic trees. Because a space of…

Combinatorics · Mathematics 2020-05-15 Ruriko Yoshida

The phylogenetic Mean Pairwise Distance (MPD) is one of the most popular measures for computing the phylogenetic distance between a given group of species. More specifically, for a phylogenetic tree T and for a set of species R represented…

Quantitative Methods · Quantitative Biology 2013-08-02 Constantinos Tsirogiannis , Brody Sandel

We describe a kernel of size 9k-8 for the NP-hard problem of computing the Tree Bisection and Reconnect (TBR) distance k between two unrooted binary phylogenetic trees. We achieve this by extending the existing portfolio of reduction rules…

Data Structures and Algorithms · Computer Science 2022-09-21 Steven Kelk , Simone Linz , Ruben Meuwese

Typing methods are widely used in the surveillance of infectious diseases, outbreaks investigation and studies of the natural history of an infection. And their use is becoming standard, in particular with the introduction of High…

Data Structures and Algorithms · Computer Science 2020-06-16 Cátia Vaz , Marta Nascimento , João A. Carriço , Tatiana Rocher , Alexandre P. Francisco

The Robinson-Foulds (RF) metric is arguably the most widely used measure of phylogenetic tree similarity, despite its well-known shortcomings: For example, moving a single taxon in a tree can result in a tree that has maximum distance to…

Data Structures and Algorithms · Computer Science 2013-08-02 Sebastian Böcker , Stefan Canzar , Gunnar W. Klau

We present two algorithms for computing the geodesic distance between phylogenetic trees in tree space, as introduced by Billera, Holmes, and Vogtmann (2001). We show that the possible combinatorial types of shortest paths between two trees…

Combinatorics · Mathematics 2011-06-08 Megan Owen

Phylogenetic trees provide a fundamental representation of evolutionary relationships, yet the combinatorial explosion of possible tree topologies renders inference computationally challenging. Classical approaches to characterizing tree…

Populations and Evolution · Quantitative Biology 2025-12-29 Samir Bhatt , John Sabol , Papri Dey , Matthew J. Penn , David Duchene , Ruriko Yoshida

Comparative analyses of phylogenetic trees typically require identical taxon sets, however, in practice, trees often include distinct but overlapping taxa. Pruning non-shared leaves discards phylogenetic signal, whereas tree completion can…

Populations and Evolution · Quantitative Biology 2026-04-28 Aleksandr Koshkarov , Nadia Tahiri

Ultametrics are an important class of distances used in applications such as phylogenetics, clustering and classification theory. Ultrametrics are essentially distances that can be represented by an edge-weighted rooted tree so that all of…

Combinatorics · Mathematics 2026-02-13 Katharina T. Huber , Vincent Moulton , Guillaume E. Scholz

The tropical variety of a $d$-dimensional prime ideal in a polynomial ring with complex coefficients is a pure $d$-dimensional polyhedral fan. This fan is shown to be connected in codimension one. We present algorithmic tools for computing…

Algebraic Geometry · Mathematics 2009-12-16 Tristram Bogart , Anders Jensen , David Speyer , Bernd Sturmfels , Rekha Thomas

The matching distance is a computationally tractable topological measure to compare multi-filtered simplicial complexes. We design efficient algorithms for approximating the matching distance of two bi-filtered complexes to any desired…

Computational Geometry · Computer Science 2020-04-02 Michael Kerber , Arnur Nigmetov

Phylogenetic networks are a type of directed acyclic graph that represent how a set $X$ of present-day species are descended from a common ancestor by processes of speciation and reticulate evolution. In the absence of reticulate evolution,…

Combinatorics · Mathematics 2017-08-11 Andrew Francis , Charles Semple , Mike Steel

We propose a statistical method to test whether two phylogenetic trees with given alignments are significantly incongruent. Our method compares the two distributions of phylogenetic trees given by the input alignments, instead of comparing…

Populations and Evolution · Quantitative Biology 2010-04-14 Elissaveta Arnaoudova , David Haws , Peter Huggins , Jerzy W. Jaromczyk , Neil Moore , Chris Schardl , Ruriko Yoshida

The type A cluster configuration space, commonly known as $\mathcal M_{0,n}$, is the very affine part of the binary geometry associated with the associahedron. The tropicalization of $\mathcal M_{0,n}$ can be realized as the space of…

Algebraic Geometry · Mathematics 2025-02-06 Shelby Cox , Igor Makhlin

Deep neural networks show great success when input vectors are in an Euclidean space. However, those classical neural networks show a poor performance when inputs are phylogenetic trees, which can be written as vectors in the tropical…

Discrete Mathematics · Computer Science 2023-09-26 Ruriko Yoshida , Georgios Aliatimis , Keiji Miura

The paper studies intrinsic geometry in the tropical plane. Tropical structure in the real affine $n$-space is determined by the integer tangent vectors. Tropical isomorphisms are affine transformations preserving the integer lattice of the…

Algebraic Geometry · Mathematics 2024-01-10 Grigory Mikhalkin , Mikhail Shkolnikov

Tree comparison metrics have proven to be an invaluable aide in the reconstruction and analysis of phylogenetic (evolutionary) trees. The path-length distance between trees is a particularly attractive measure as it reflects differences in…

Data Structures and Algorithms · Computer Science 2018-11-05 David Bryant , Celine Scornavacca

Clustering is a popular form of unsupervised learning for geometric data. Unfortunately, many clustering algorithms lead to cluster assignments that are hard to explain, partially because they depend on all the features of the data in a…

Machine Learning · Computer Science 2020-09-23 Sanjoy Dasgupta , Nave Frost , Michal Moshkovitz , Cyrus Rashtchian

In this work we study the interleaving distance between merge trees from a combinatorial point of view. We use a particular type of matching between trees to obtain a novel formulation of the distance. With such formulation, we tackle the…

Combinatorics · Mathematics 2024-11-11 Matteo Pegoraro

Let X be a plane in a torus over an algebraically closed field K, with tropicalization the matroidal fan Sigma. In this paper we present an algorithm which completely solves the question whether a given one-dimensional balanced polyhedral…

Algebraic Geometry · Mathematics 2014-12-10 Anna Lena Birkmeyer , Andreas Gathmann