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Related papers: MINT: Multimodal Imaging-to-Speech Knowledge Trans…

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Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

Quantitative Methods · Quantitative Biology 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

Alzheimer's disease (AD) poses significant global health challenges due to its increasing prevalence and associated societal costs. Early detection and diagnosis of AD are critical for delaying progression and improving patient outcomes.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Arianna Francesconi , Lazzaro di Biase , Donato Cappetta , Fabio Rebecchi , Paolo Soda , Rosa Sicilia , Valerio Guarrasi

Brain-related research topics in artificial intelligence have recently gained popularity, particularly due to the expansion of what multimodal architectures can do from computer vision to natural language processing. Our main goal in this…

Neurons and Cognition · Quantitative Biology 2024-10-01 Youssef Hmamouche , Ismail Chihab , Lahoucine Kdouri , Amal El Fallah Seghrouchni

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

In the field of Alzheimer's disease diagnosis, segmentation and classification tasks are inherently interconnected. Sharing knowledge between models for these tasks can significantly improve training efficiency, particularly when training…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Ke Chen , Yifeng Wang , Yufei Zhou , Haohan Wang

Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Rosemary He , Gabriella Ang , Daniel Tward

Neuropsychiatric disorders, such as Alzheimer's disease (AD), depression, and autism spectrum disorder (ASD), are characterized by linguistic and acoustic abnormalities, offering potential biomarkers for early detection. Despite the promise…

Computation and Language · Computer Science 2025-12-25 Zhongren Dong , Haotian Guo , Weixiang Xu , Huan Zhao , Zixing Zhang

Alzheimer's disease (AD), defined as an abnormal buildup of amyloid plaques and tau tangles in the brain can be diagnosed with high accuracy based on protein biomarkers via PET or CSF analysis. However, due to the invasive nature of…

Machine Learning · Computer Science 2026-01-27 Megan A. Witherow , Michael L. Evans , Ahmed Temtam , Hamid R. Okhravi , Khan M. Iftekharuddin

Alzheimer's Disease (AD) is a progressive disease preceded by Mild Cognitive Impairment (MCI). Early detection of AD is crucial for making treatment decisions. However, most of the literature on computer-assisted detection of AD focuses on…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Misgina Tsighe Hagos , Niamh Belton , Ronan P. Killeen , Kathleen M. Curran , Brian Mac Namee

Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…

Computer Vision and Pattern Recognition · Computer Science 2014-04-29 Fayao Liu , Chunhua Shen

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

Computation and Language · Computer Science 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

Synthesizing amyloid PET scans from the more widely available and accessible structural MRI modality offers a promising, cost-effective approach for large-scale Alzheimer's Disease (AD) screening. This is motivated by evidence that, while…

Image and Video Processing · Electrical Eng. & Systems 2025-11-12 Alec Sargood , Lemuel Puglisi , James H. Cole , Neil P. Oxtoby , Daniele Ravì , Daniel C. Alexander

Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Siva Manohar Reddy Kesu , Neelam Sinha , Hariharan Ramasangu , Thomas Gregor Issac

Owing to its pristine soft-tissue contrast and high resolution, structural magnetic resonance imaging (MRI) is widely applied in neurology, making it a valuable data source for image-based machine learning (ML) and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Merel Kuijs , Catherine R. Jutzeler , Bastian Rieck , Sarah C. Brüningk

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Brain transcriptomics provides insights into the molecular mechanisms by which the brain coordinates its functions and processes. However, existing multimodal methods for predicting Alzheimer's disease (AD) primarily rely on imaging and…

Artificial Intelligence · Computer Science 2025-04-03 Shan Cong , Zhoujie Fan , Hongwei Liu , Yinghan Zhang , Xin Wang , Haoran Luo , Xiaohui Yao

Speech pauses, alongside content and structure, offer a valuable and non-invasive biomarker for detecting dementia. This work investigates the use of pause-enriched transcripts in transformer-based language models to differentiate the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-08-28 Franziska Braun , Sebastian P. Bayerl , Florian Hönig , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Estimated brain age from magnetic resonance image (MRI) and its deviation from chronological age can provide early insights into potential neurodegenerative diseases, supporting early detection and implementation of prevention strategies.…

Introduction: We present a screening method for early dementia using features based on sound objects as voice biomarkers. Methods: The final dataset used for machine learning models consisted of 266 observations, with a distribution of 186…

High-dimensional structural MRI (sMRI) images are widely used for Alzheimer's Disease (AD) diagnosis. Most existing methods for sMRI representation learning rely on 3D architectures (e.g., 3D CNNs), slice-wise feature extraction with late…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Dexuan Ding , Ciyuan Peng , Endrowednes Kuantama , Jingcai Guo , Jia Wu , Jian Yang , Amin Beheshti , Ming-Hsuan Yang , Yuankai Qi
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