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Photoacoustic computed tomography (PACT) is emerging as a new technique for functional brain imaging, primarily due to its capabilities in label-free hemodynamic imaging. Despite its potential, the transcranial application of PACT has…

Photoacoustic tomography (PAT) is a nonionizing imaging modality capable of acquiring high contrast and resolution images of optical absorption at depths greater than traditional optical imaging techniques. Practical considerations with…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Steven Guan , Amir A. Khan , Siddhartha Sikdar , Parag V. Chitnis

Photo-acoustic tomography is a coupled-physics (hybrid) medical imaging modality that aims to reconstruct optical parameters in biological tissues from ultrasound measurements. As propagating light gets partially absorbed, the resulting…

Analysis of PDEs · Mathematics 2020-01-08 Guillaume Bal , Adrian Kirkeby

Photoacoustic (PA) computed tomography (PACT) shows great potentials in various preclinical and clinical applications. A great number of measurements are the premise that obtains a high-quality image, which implies a low imaging rate or a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Hengrong Lan , Juze Zhang , Changchun Yang , Fei Gao

Over the past decades, thermal ablation procedures such as high intensity focused ultrasound (HIFU) have been developed vaporize cancerous tissues in a focal area. Thermal ablation has the potential to non-invasively eliminate tumors and…

Medical Physics · Physics 2022-03-01 Nathan Wang , Petteri Haverinen

We demonstrate dual-frequency absorption spectroscopy (DFAS) using laser-cooled 87Rb and 85Rb atoms. Doppler-free resonances with high-contrast are produced, which suggest the suitability of using dual-frequency absorption spectroscopy…

Atomic Physics · Physics 2025-08-26 Gour Pati , Mauricio Pulido , Fredrik K. Fatemi , Gustavo Acosta , Renu Tripathi

Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging.…

Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore…

Optics · Physics 2026-01-06 David C. Garrett , Lihong V. Wang

Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics like chemotherapy and radiotherapy. In this study, we propose a promising thermostatic…

Medical Physics · Physics 2021-09-14 Yuchan Wang , Yuening Wang , Yuan Jie , Paul Carson

Dynamic Photoacoustic Computed Tomography (PACT) is an important imaging technique for monitoring physiological processes, capable of providing high-contrast images of optical absorption at much greater depths than traditional optical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Youshen Xiao , Yiling Shi , Ruixi Sun , Hongjiang Wei , Fei Gao , Yuyao Zhang

Photoacoustic imaging (PAI) is a powerful imaging modality that relies on the PA effect. PAI works on the principle of electromagnetic energy absorption by the exogenous contrast agents and/or endogenous molecules present in the biological…

Optics · Physics 2020-12-16 Mohsin Zafar , Qiuyun Xu , Rayyan Manwar

Thermoacoustic tomography (TAT) is an imaging modality based on the thermoacoustic effect. In TAT, a short microwave or radio wave pulse is directed to the imaged target. The energy of the electromagnetic pulse is absorbed depending on the…

Computational Physics · Physics 2025-11-11 Teemu Sahlström , Tanja Tarvainen

Photoacoustic imaging systems offer a platform with high resolution to explore body tissues, food, and artwork. On the other hand, plasmonics constitutes a source of resonant heating and thermal expansion to generate acoustic waves.…

Applied Physics · Physics 2022-08-29 Ricardo Martín Abraham-Ekeroth

Quantitative photoacoustic tomography (QPAT) is a recent hybrid imaging modality that couples optical tomography with ultrasound imaging to achieve high resolution imaging of optical properties of scattering media. Image reconstruction in…

Analysis of PDEs · Mathematics 2015-09-02 Tian Ding , Kui Ren , Sarah Vallelian

In this paper, we propose a hybrid method to reconstruct the absorption coefficient by fluorescence photoacoustic tomography (FPAT), which combines a squeeze iterative method (SIM) and a nonlinear optimization method. The SIM is to use two…

Numerical Analysis · Mathematics 2019-01-30 Chao Wang , Tie Zhou

We consider the reconstruction of optical parameters in a domain of interest from photoacoustic data. Photoacoustic tomography (PAT) radiates high frequency electromagnetic waves into the domain and measures acoustic signals emitted by the…

Mathematical Physics · Physics 2015-05-14 Guillaume Bal , Alexandre Jollivet , Vincent Jugnon

Detecting coherent phonons pose different challenges compared to coherent photons due to the much stronger interaction between phonons and matter. This is especially true for high frequency heat carrying phonons, which are intrinsic lattice…

Mesoscale and Nanoscale Physics · Physics 2018-03-14 Ding Ding , Xiaobo Yin , Baowen Li

Phase-contrast imaging is an emerging technology that may increase the signal-difference-to-noise ratio in medical imaging. One of the most promising phase-contrast techniques is Talbot interferometry, which, combined with energy-sensitive…

Photoacoustic imaging (PAI) represents an innovative biomedical imaging modality that harnesses the advantages of optical resolution and acoustic penetration depth while ensuring enhanced safety. Despite its promising potential across a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lei Wang , Weiming Zeng , Kai Long , Hongyu Chen , Rongfeng Lan , Li Liu , Wai Ting Siok , Nizhuan Wang

Quantitative photo-acoustic tomography (QPAT) seeks to reconstruct a distribution of optical attenuation coefficients inside a sample from a set of time series of pressure data that is measured outside the sample. The associated inverse…

Optimization and Control · Mathematics 2019-09-04 Ashkan Javaherian , Sean Holman