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Transformer-based language models have set new benchmarks across a wide range of NLP tasks, yet reliably estimating the uncertainty of their predictions remains a significant challenge. Existing uncertainty estimation (UE) techniques often…

Machine Learning · Computer Science 2024-09-18 Elizaveta Kostenok , Daniil Cherniavskii , Alexey Zaytsev

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

Foundation models have recently emerged as powerful feature extractors in computational pathology, yet they typically omit mechanisms for leveraging the global spatial structure of tissues and the local contextual relationships among…

Transfer learning boosts the performance of medical image analysis by enabling deep learning (DL) on small datasets through the knowledge acquired from large ones. As the number of DL architectures explodes, exhaustively attempting all…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Levy Chaves , Alceu Bissoto , Eduardo Valle , Sandra Avila

Metal-organic frameworks (MOFs) are porous, crystalline materials with high surface area, adjustable porosity, and structural tunability, making them ideal for diverse applications. However, traditional experimental and computational…

Biomolecules · Quantitative Biology 2024-12-17 Dong Chen , Chun-Long Chen , Guo-Wei Wei

Extensive research has been conducted on assessing grasp stability, a crucial prerequisite for achieving optimal grasping strategies, including the minimum force grasping policy. However, existing works employ basic feature-level fusion…

Robotics · Computer Science 2023-08-03 Zhuangzhuang Zhang , Zhenning Zhou , Haili Wang , Zhinan Zhang , Huang Huang , Qixin Cao

Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Haotian Wang , Min Xian , Aleksandar Vakanski

Pancreas segmentation in medical image processing is a persistent challenge due to its small size, low contrast against adjacent tissues, and significant topological variations. Traditional level set methods drive boundary evolution using…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yue Gou , Fanghui Song , Yuming Xing , Shengzhu Shi , Zhichang Guo , Boying Wu

Automated medical diagnosis through image-based neural networks has increased in popularity and matured over years. Nevertheless, it is confined by the scarcity of medical images and the expensive labor annotation costs. Self-Supervised…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Luffina C. Huang , Darren J. Chiu , Manish Mehta

Accurate brain tumor segmentation is crucial for neuro-oncology diagnosis and treatment planning. Deep learning methods have made significant progress, but automatic segmentation still faces challenges, including tumor morphological…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Mingda Zhang

Segmentation is the identification of anatomical regions of interest, such as organs, tissue, and lesions, serving as a fundamental task in computer-aided diagnosis in medical imaging. Although deep learning models have achieved remarkable…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Tianyi Ren , Daniel Low , Pittra Jaengprajak , Juampablo Heras Rivera , Jacob Ruzevick , Mehmet Kurt

The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning…

Foundation models (FMs) have achieved remarkable success across a wide range of applications, from image classification to natural langurage processing, but pose significant challenges for deployment at edge. This has sparked growing…

Machine Learning · Computer Science 2025-07-17 Muhammad Azlan Qazi , Alexandros Iosifidis , Qi Zhang

Transition Matching (TM) is an emerging paradigm for generative modeling that generalizes diffusion and flow-matching models as well as continuous-state autoregressive models. TM, similar to previous paradigms, gradually transforms noise…

Machine Learning · Computer Science 2025-12-16 Uriel Singer , Yaron Lipman

Recent progress on intelligent fault diagnosis (IFD) has greatly depended on deep representation learning and plenty of labeled data. However, machines often operate with various working conditions or the target task has different…

Signal Processing · Electrical Eng. & Systems 2021-11-23 Zhibin Zhao , Qiyang Zhang , Xiaolei Yu , Chuang Sun , Shibin Wang , Ruqiang Yan , Xuefeng Chen

Robust prediction of molecular properties under extreme out-of-distribution (OOD) scenarios is a pivotal bottleneck in AI-driven drug discovery. Current scaffold-splitting protocols fail to obstruct microscopic semantic overlap,…

Machine Learning · Computer Science 2026-05-15 Zhuohao Lin , Kun Li , Jiameng Chen , Jiajun Yu , Duanhua Cao , Yizhen Zheng , Wenbin Hu

Automatic evaluation of the goodness of Generative Adversarial Networks (GANs) has been a challenge for the field of machine learning. In this work, we propose a distance complementary to existing measures: Topology Distance (TD), the main…

Machine Learning · Computer Science 2020-02-28 Danijela Horak , Simiao Yu , Gholamreza Salimi-Khorshidi

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

Recent advances in cellular research demonstrate that scRNA-seq characterizes cellular heterogeneity, while spatial transcriptomics reveals the spatial distribution of gene expression. Cell representation is the fundamental issue in the two…

Genomics · Quantitative Biology 2025-01-16 Kai Zheng , Shaokai Wang , Yunpei Xu , Qiming Lei , Qichang Zhao , Xiao Liang , Qilong Feng , Yaohang Li , Min Li , Jinhui Xu , Jianxin Wang

Multi-modal foundation models are typically trained on millions of pairs of natural images and text captions, frequently obtained through web-crawling approaches. Although such models depict excellent generative capabilities, they do not…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Pierre Chambon , Christian Bluethgen , Curtis P. Langlotz , Akshay Chaudhari