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Understanding generalization and robustness of machine learning models fundamentally relies on assuming an appropriate metric on the data space. Identifying such a metric is particularly challenging for non-Euclidean data such as graphs.…

Machine Learning · Computer Science 2022-10-06 Ching-Yao Chuang , Stefanie Jegelka

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Weiming Chen , Xitong Ling , Xidong Wang , Zhenyang Cai , Yijia Guo , Mingxi Fu , Ziyi Zeng , Minxi Ouyang , Jiawen Li , Yizhi Wang , Tian Guan , Benyou Wang , Yonghong He

Versatile medical image segmentation (VMIS) targets the segmentation of multiple classes, while obtaining full annotations for all classes is often impractical due to the time and labor required. Leveraging partially labeled datasets (PLDs)…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Shengqian Zhu , Jiafei Wu , Xiaogang Xu , Chengrong Yu , Ying Song , Zhang Yi , Guangjun Li , Junjie Hu

Many machine learning methods have been recently developed to circumvent the high computational cost of the gradient-based topology optimization. These methods typically require extensive and costly datasets for training, have a difficult…

Machine Learning · Computer Science 2021-05-10 Mohammad Mahdi Behzadi , Horea T. Ilies

In medical contexts, the imbalanced data distribution in long-tailed datasets, due to scarce labels for rare diseases, greatly impairs the diagnostic accuracy of deep learning models. Recent multimodal text-image supervised foundation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Sirui Li , Li Lin , Yijin Huang , Pujin Cheng , Xiaoying Tang

While spatial transcriptomics (ST) has advanced our understanding of gene expression in tissue context, its high experimental cost limits its large-scale application. Predicting ST from pathology images is a promising, cost-effective…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Zhiceng Shi , Changmiao Wang , Jun Wan , Wenwen Min

Recently, topological deep learning (TDL), which integrates algebraic topology with deep neural networks, has achieved tremendous success in processing point-cloud data, emerging as a promising paradigm in data science. However, TDL has not…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Xiang Liu , Zhe Su , Yongyi Shi , Yiying Tong , Ge Wang , Guo-Wei Wei

The published literature on topology optimization has exploded over the last two decades to include methods that use shape and topological derivatives or evolutionary algorithms formulated on various geometric representations and…

Machine Learning · Computer Science 2021-02-16 MohammadMahdi Behzadi , Horea T. Ilies

Traditional deep learning methods in medical imaging often focus solely on segmentation or classification, limiting their ability to leverage shared information. Multi-task learning (MTL) addresses this by combining both tasks through…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Phuoc-Nguyen Bui , Duc-Tai Le , Junghyun Bum , Hyunseung Choo

Fine-tuning pre-trained models has become a cornerstone of modern machine learning, allowing practitioners to achieve high performance with limited labeled data. In surgical video analysis, where expert annotations are especially…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Prabhant Singh , Yiping Li , Yasmina Al Khalil

Object recognition is a key enabler across industry and defense. As technology changes, algorithms must keep pace with new requirements and data. New modalities and higher resolution sensors should allow for increased algorithm robustness.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-24 Samuel Rivera , Joel Klipfel , Deborah Weeks

In recent years, pre-trained large language models have achieved remarkable success across diverse tasks. Besides the pivotal role of self-supervised pre-training, their effectiveness in downstream applications also depends critically on…

Artificial Intelligence · Computer Science 2026-03-04 Qi Zhang , Yifei Wang , Xiaohan Wang , Jiajun Chai , Guojun Yin , Wei Lin , Yisen Wang

Task-specific deep learning models in histopathology offer promising opportunities for improving diagnosis, clinical research, and precision medicine. However, development of such models is often limited by availability of high-quality…

Transfer learning aims to learn classifiers for a target domain by transferring knowledge from a source domain. However, due to two main issues: feature discrepancy and distribution divergence, transfer learning can be a very difficult…

Machine Learning · Computer Science 2022-09-05 Md Geaur Rahman , Md Zahidul Islam

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

Medical image segmentation driven by free-text clinical instructions is a critical frontier in computer-aided diagnosis. However, existing multimodal and foundation models struggle with the semantic ambiguity of clinical reports and fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Chenyu Xue , Yiran Liu , Mian Zhou , Jionglong Su , Zhixiang Lu

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

We introduce a framework for analyzing topological tipping in time-evolutionary point clouds by extending the recently proposed Topological Optimal Transport (TpOT) distance. While TpOT unifies geometric, homological, and higher-order…

Machine Learning · Statistics 2026-03-18 Yixin Wang , Ting Gao , Jinqiao Duan

Scarcity of labeled histopathology data limits the applicability of deep learning methods to under-profiled cancer types and labels. Transfer learning allows researchers to overcome the limitations of small datasets by pre-training machine…

Computer Vision and Pattern Recognition · Computer Science 2022-04-21 Anna Yeaton , Rahul G. Krishnan , Rebecca Mieloszyk , David Alvarez-Melis , Grace Huynh

This paper explores and enhances the application of Transfer Learning (TL) for multilabel image classification in medical imaging, focusing on brain tumor class and diabetic retinopathy stage detection. The effectiveness of TL-using…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Md. Zehan Alam , Tonmoy Roy , H. M. Nahid Kawsar , Iffat Rimi