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Automated generation of diagnostic pathology reports directly from whole slide images (WSIs) is an emerging direction in computational pathology. Translating high-resolution tissue patterns into clinically coherent text remains difficult…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Noorul Wahab , Nasir Rajpoot

Generating diagnostic text from histopathology whole slide images (WSIs) is challenging due to the gigapixel scale of the input and the requirement for precise, domain specific language. We propose a hierarchical vision language framework…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Ahmet Halici , Ece Tugba Cebeci , Musa Balci , Mustafa Cini , Serkan Sokmen

Automated pathology report generation from Whole Slide Images (WSIs) faces two key challenges: (1) lack of semantic content in visual features and (2) inherent information redundancy in WSIs. To address these issues, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Ling Zhang , Boxiang Yun , Qingli Li , Yan Wang

Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Deep learning for histopathology has been successfully used for disease classification, image segmentation and more. However, combining image and text modalities using current state-of-the-art methods has been a challenge due to the high…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Saurav Sengupta , Donald E. Brown

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

Whole slide image (WSI) classification has emerged as a powerful tool in computational pathology, but remains constrained by domain shifts, e.g., due to different organs, diseases, or institution-specific variations. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Pratibha Kumari , Daniel Reisenbüchler , Afshin Bozorgpour , Nadine S. Schaadt , Friedrich Feuerhake , Dorit Merhof

The rapid proliferation of wireless devices makes robust identity authentication essential. Radio Frequency Fingerprinting (RFF) exploits device-specific, hard-to-forge physical-layer impairments for identification, and is promising for IoT…

Signal Processing · Electrical Eng. & Systems 2026-01-07 Rundong Jiang , Jun Hu , Yunqi Song , Zhiyuan Xie , Shiyou Xu

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Pingyi Chen , Honglin Li , Chenglu Zhu , Sunyi Zheng , Zhongyi Shui , Lin Yang

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Histopathological whole slide images (WSIs) classification has become a foundation task in medical microscopic imaging processing. Prevailing approaches involve learning WSIs as instance-bag representations, emphasizing significant…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Jiawen Li , Yuxuan Chen , Hongbo Chu , Qiehe Sun , Tian Guan , Anjia Han , Yonghong He

Pathology is essential for cancer diagnosis, with multiple instance learning (MIL) widely used for whole slide image (WSI) analysis. WSIs exhibit a natural hierarchy -- patches, regions, and slides -- with distinct semantic associations.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Peixiang Huang , Yanyan Huang , Weiqin Zhao , Junjun He , Lequan Yu

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

The fine-grained annotations in whole slide images (WSIs) show the boundaries of various pathological regions. However, generating such detailed annotation is often costly, whereas the coarse annotations are relatively simpler to produce.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Bingjian Yao , Weiping Lin , Yan He , Zheng Wang , Liangsheng Wang

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Yash Sharma , Lubaina Ehsan , Sana Syed , Donald E. Brown

Automated medical report generation has demonstrated the potential to significantly reduce the workload associated with time-consuming medical reporting. Recent generative representation learning methods have shown promise in integrating…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shuchang Ye , Mingyuan Meng , Mingjian Li , Dagan Feng , Usman Naseem , Jinman Kim
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