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In this paper, we study a generalization of the two-groups model in the presence of covariates --- a problem that has recently received much attention in the statistical literature due to its applicability in multiple hypotheses testing…

Methodology · Statistics 2019-02-01 Nabarun Deb , Sujayam Saha , Adityanand Guntuboyina , Bodhisattva Sen

Many scientific questions rely on determining whether two sequences of event times are associated. This article introduces a likelihood ratio test which can be parameterised in several ways to detect different forms of dependence. A common…

Methodology · Statistics 2014-12-23 Patrick Rubin-Delanchy , Nicholas A. Heard

Parametric hypothesis testing associated with two independent samples arises frequently in several applications in biology, medical sciences, epidemiology, reliability and many more. In this paper, we propose robust Wald-type tests for…

Methodology · Statistics 2019-05-09 Abhik Ghosh , Nirian Martin , Ayanendranath Basu , Leandro Pardo

We show how to deal with uncertainties on the Standard Model predictions in an agnostic new physics search strategy that exploits artificial neural networks. Our approach builds directly on the specific Maximum Likelihood ratio treatment of…

High Energy Physics - Phenomenology · Physics 2021-11-29 Raffaele Tito d'Agnolo , Gaia Grosso , Maurizio Pierini , Andrea Wulzer , Marco Zanetti

The DerSimonian-Laird (DL) weighted average method has been widely used for estimation of a pooled effect size from an aggregated data meta-analysis study. It is mainly criticized for its underestimation of the standard error of the pooled…

Methodology · Statistics 2021-04-09 Osama Almalik , Edwin R. van den Heuvel

We consider a class of hypothesis testing problems where the null hypothesis postulates $M$ distributions for the observed data, and there is only one possible distribution under the alternative. We show that one can use a stochastic mirror…

The present paper answers the following questions related with high-dimensional manova: (i) is it possible to develop a likelihood ratio test for high-dimensional manova? (ii) would such test perform well? (iii) would it be able to…

Methodology · Statistics 2025-07-03 Carlos A. Coelho

Consistently checking the statistical significance of experimental results is the first mandatory step towards reproducible science. This paper presents a hitchhiker's guide to rigorous comparisons of reinforcement learning algorithms.…

Methodology · Statistics 2022-08-30 Cédric Colas , Olivier Sigaud , Pierre-Yves Oudeyer

Hypothesis testing for the slope function in functional linear regression is of both practical and theoretical interest. We develop a novel test for the nullity of the slope function, where testing the slope function is transformed into…

Methodology · Statistics 2024-04-02 Yinan Lin , Zhenhua Lin

This paper considers the design of a minimax test for two hypotheses where the actual probability densities of the observations are located in neighborhoods obtained by placing a bound on the relative entropy between actual and nominal…

Information Theory · Computer Science 2016-11-18 Bernard C. Levy

In this work we propose a framework for constructing goodness of fit tests in both low and high-dimensional linear models. We advocate applying regression methods to the scaled residuals following either an ordinary least squares or Lasso…

Methodology · Statistics 2017-04-11 Rajen D. Shah , Peter Bühlmann

Large Language Models (LLMs) are demonstrating outstanding potential for tasks such as text generation, summarization, and classification. Given that such models are trained on a humongous amount of online knowledge, we hypothesize that…

Software Engineering · Computer Science 2024-03-18 Jiahui Wu , Chengjie Lu , Aitor Arrieta , Tao Yue , Shaukat Ali

In this work, we address the question of how to enhance signal-agnostic searches by leveraging multiple testing strategies. Specifically, we consider hypothesis tests relying on machine learning, where model selection can introduce a bias…

High Energy Physics - Phenomenology · Physics 2024-08-23 Gaia Grosso , Marco Letizia

Estimation of heterogeneous treatment effects is an essential component of precision medicine. Model and algorithm-based methods have been developed within the causal inference framework to achieve valid estimation and inference. Existing…

Methodology · Statistics 2021-05-10 Ruohong Li , Honglang Wang , Wanzhu Tu

These notes survey and explore an emerging method, which we call the low-degree method, for predicting and understanding statistical-versus-computational tradeoffs in high-dimensional inference problems. In short, the method posits that a…

Statistics Theory · Mathematics 2019-07-29 Dmitriy Kunisky , Alexander S. Wein , Afonso S. Bandeira

What can be considered an appropriate statistical method for the primary analysis of a randomized clinical trial (RCT) with a time-to-event endpoint when we anticipate non-proportional hazards owing to a delayed effect? This question has…

Methodology · Statistics 2023-04-18 José L. Jiménez , Isobel Barrott , Francesca Gasperoni , Dominic Magirr

High-dimensional statistical inference with general estimating equations are challenging and remain less explored. In this paper, we study two problems in the area: confidence set estimation for multiple components of the model parameters,…

Methodology · Statistics 2021-04-28 Jinyuan Chang , Song Xi Chen , Cheng Yong Tang , Tong Tong Wu

We consider the problem of detecting sparse heterogeneous mixtures in a two-sample setting from a nonparametric perspective, where the effect manifests itself as a positive shift. We suggest a two-sample higher criticism test, and show that…

Statistics Theory · Mathematics 2020-11-30 Rong Huang

We study the simple hypothesis testing problem for the drift coefficient for stochastic fractional heat equation driven by additive noise. We introduce the notion of asymptotically the most powerful test, and find explicit forms of such…

Statistics Theory · Mathematics 2014-12-22 Igor Cialenco , Liaosha Xu

In this work, we revisit the one- and two-sample testing problems: binary hypothesis testing in which one or both distributions are unknown. For the one-sample test, we provide a more streamlined proof of the asymptotic optimality of…

Information Theory · Computer Science 2026-04-21 Arick Grootveld , Biao Chen , Venkata Gandikota