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Deep Learning based methods have emerged as the indisputable leaders for virtually all image restoration tasks. Especially in the domain of microscopy images, various content-aware image restoration (CARE) approaches are now used to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Mangal Prakash , Alexander Krull , Florian Jug

Machine learning models have had discernible achievements in a myriad of applications. However, most of these models are black-boxes, and it is obscure how the decisions are made by them. This makes the models unreliable and untrustworthy.…

Machine Learning · Computer Science 2020-03-23 Raha Moraffah , Mansooreh Karami , Ruocheng Guo , Adrienne Raglin , Huan Liu

We study causal discovery from observational data in linear Gaussian systems affected by \emph{mixed latent confounding}, where some unobserved factors act broadly across many variables while others influence only small subsets. This…

Machine Learning · Computer Science 2026-01-01 Amir Asiaee , Samhita Pal , James O'quinn , James P. Long

Studies show that the representations learned by deep neural networks can be transferred to similar prediction tasks in other domains for which we do not have enough labeled data. However, as we transition to higher layers in the model, the…

Machine Learning · Computer Science 2019-10-29 Raha Moraffah , Kai Shu , Adrienne Raglin , Huan Liu

Biological signals of interest in high-dimensional data are often masked by dominant variation shared across conditions. This variation, arising from baseline biological structure or technical effects, can prevent standard dimensionality…

Machine Learning · Computer Science 2026-02-27 Yixuan Li , Archer Y. Yang , Yue Li

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

Convolutional neural network based systems have largely failed to be adopted in many high-risk application areas, including healthcare, military, security, transportation, finance, and legal, due to their highly uninterpretable "black-box"…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Rodney LaLonde , Drew Torigian , Ulas Bagci

Cell counting in biomedical imaging is pivotal for various clinical applications, yet the interpretability of deep learning models in this domain remains a significant challenge. We propose a novel prototype-based method for interpretable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdurahman Ali Mohammed , Wallapak Tavanapong , Catherine Fonder , Donald S. Sakaguchi

Local explanation frameworks aim to rationalize particular decisions made by a black-box prediction model. Existing techniques are often restricted to a specific type of predictor or based on input saliency, which may be undesirably…

Machine Learning · Computer Science 2019-02-12 Brandon Carter , Jonas Mueller , Siddhartha Jain , David Gifford

Unbiased data synthesis is crucial for evaluating causal discovery algorithms in the presence of unobserved confounding, given the scarcity of real-world datasets. A common approach, implicit parameterization, encodes unobserved confounding…

Machine Learning · Statistics 2025-04-02 Xudong Sun , Alex Markham , Pratik Misra , Carsten Marr

Benefited from the deep learning, image Super-Resolution has been one of the most developing research fields in computer vision. Depending upon whether using a discriminator or not, a deep convolutional neural network can provide an image…

Computer Vision and Pattern Recognition · Computer Science 2020-04-28 Zhi-Song Liu , Wan-Chi Siu , Li-Wen Wang , Chu-Tak Li , Marie-Paule Cani , Yui-Lam Chan

As deep vision models' popularity rapidly increases, there is a growing emphasis on explanations for model predictions. The inherently explainable attribution method aims to enhance the understanding of model behavior by identifying the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Xianren Zhang , Dongwon Lee , Suhang Wang

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Eduardo Pinho , Carlos Costa

Existing algorithms for explaining the output of image classifiers perform poorly on inputs where the object of interest is partially occluded. We present a novel, black-box algorithm for computing explanations that uses a principled…

Machine Learning · Computer Science 2021-09-08 Hana Chockler , Daniel Kroening , Youcheng Sun

Causal disentanglement aims to uncover a representation of data using latent variables that are interrelated through a causal model. Such a representation is identifiable if the latent model that explains the data is unique. In this paper,…

Causal discovery, beyond the inference of a network as a collection of connected dots, offers a crucial functionality in scientific discovery using artificial intelligence. The questions that arise in multiple domains, such as physics,…

Machine Learning · Computer Science 2021-06-03 M. Ali Vosoughi , Axel Wismuller

Computer vision systems in real-world applications need to be robust to partial occlusion while also being explainable. In this work, we show that black-box deep convolutional neural networks (DCNNs) have only limited robustness to partial…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Adam Kortylewski , Qing Liu , Angtian Wang , Yihong Sun , Alan Yuille

There have been several post-hoc explanation approaches developed to explain pre-trained black-box neural networks. However, there is still a gap in research efforts toward designing neural networks that are inherently explainable. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Subash Khanal , Benjamin Brodie , Xin Xing , Ai-Ling Lin , Nathan Jacobs

Concept-based models are an emerging paradigm in deep learning that constrains the inference process to operate through human-interpretable variables, facilitating explainability and human interaction. However, these architectures, on par…

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan