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It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Peide Zhu , Linbin Lu , Zhiqin Chen , Xiong Chen

Edge detection is typically viewed as a pixel-level classification problem mainly addressed by discriminative methods. Recently, generative edge detection methods, especially diffusion model based solutions, are initialized in the edge…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Caixia Zhou , Yaping Huang , Mochu Xiang , Jiahui Ren , Haibin Ling , Jing Zhang

The use of accurate scanning transmission electron microscopy (STEM) image simulation methods require large computation times that can make their use infeasible for the simulation of many images. Other simulation methods based on linear…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Nick Lawrence , Mingren Shen , Ruiqi Yin , Cloris Feng , Dane Morgan

Inferring Gene Regulatory Networks (GRNs) from gene expression data is crucial for understanding biological processes. While supervised models are reported to achieve high performance for this task, they rely on costly ground truth (GT)…

Machine Learning · Statistics 2025-06-10 Tianyu Cui , Song-Jun Xu , Artem Moskalev , Shuwei Li , Tommaso Mansi , Mangal Prakash , Rui Liao

Many modern unsupervised or semi-supervised machine learning algorithms rely on Bayesian probabilistic models. These models are usually intractable and thus require approximate inference. Variational inference (VI) lets us approximate a…

Machine Learning · Computer Science 2018-10-24 Cheng Zhang , Judith Butepage , Hedvig Kjellstrom , Stephan Mandt

Supervised machine learning algorithms play a crucial role in optical quality control within industrial production. These approaches require representative datasets for effective model training. However, while non-defective components are…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Dennis Sprute , Hanna Senke , Holger Flatt

Visual autoregressive (AR) generation models have demonstrated strong potential for image generation, yet their next-token-prediction paradigm introduces considerable inference latency. Although speculative decoding (SD) has been proven…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Haotian Dong , Ye Li , Rongwei Lu , Chen Tang , Shu-Tao Xia , Zhi Wang

It is tempting to think that machines are less prone to unfairness and prejudice. However, machine learning approaches compute their outputs based on data. While biases can enter at any stage of the development pipeline, models are…

Computer Vision and Pattern Recognition · Computer Science 2020-12-07 Patrick Esser , Robin Rombach , Björn Ommer

Pretraining language models with next-token prediction on massive text corpora has delivered phenomenal zero-shot, few-shot, transfer learning and multi-tasking capabilities on both generative and discriminative language tasks. Motivated by…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Jiahui Yu , Xin Li , Jing Yu Koh , Han Zhang , Ruoming Pang , James Qin , Alexander Ku , Yuanzhong Xu , Jason Baldridge , Yonghui Wu

Feature attribution explains Artificial Intelligence (AI) at the instance level by providing importance scores of input features' contributions to model prediction. Integrated Gradients (IG) is a prominent path attribution method for deep…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Yue Zhuo , Zhiqiang Ge

End-to-end, autoregressive model-based TTS has shown significant performance improvements over the conventional one. However, the autoregressive module training is affected by the exposure bias, or the mismatch between the different…

Computation and Language · Computer Science 2019-04-10 Haohan Guo , Frank K. Soong , Lei He , Lei Xie

Score-based generative models (SGMs) have gained prominence in sparse-view CT reconstruction for their precise sampling of complex distributions. In SGM-based reconstruction, data consistency in the score-based diffusion model ensures close…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Weiwen Wu , Yanyang Wang

Solving high-dimensional Bayesian inverse problems (BIPs) with the variational inference (VI) method is promising but still challenging. The main difficulties arise from two aspects. First, VI methods approximate the posterior distribution…

Numerical Analysis · Mathematics 2023-02-23 Yingzhi Xia , Qifeng Liao , Jinglai Li

Synthesizing consistent and photorealistic 3D scenes is an open problem in computer vision. Video diffusion models generate impressive videos but cannot directly synthesize 3D representations, i.e., lack 3D consistency in the generated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Katja Schwarz , Norman Mueller , Peter Kontschieder

We propose the Value Gradient Sampler (VGS), a diffusion sampler parameterized by value functions. VGS generates samples from an unnormalized target density (i.e., energy) by evolving randomly initialized particles along the gradient of the…

Machine Learning · Computer Science 2026-04-01 Himchan Hwang , Hyeokju Jeong , Dong Kyu Shin , Che-Sang Park , Sehee Kweon , Sangwoong Yoon , Frank Chongwoo Park

Integrated Gradients has become a popular method for post-hoc model interpretability. De-spite its popularity, the composition and relative impact of different regions of the integral path are not well understood. We explore these effects…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Vivek Miglani , Narine Kokhlikyan , Bilal Alsallakh , Miguel Martin , Orion Reblitz-Richardson

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Visual surface inspection is a challenging task owing to the highly diverse appearance of target surfaces and defective regions. Previous attempts heavily rely on vast quantities of training examples with manual annotation. However, in some…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Lingyun Gu , Lin Zhang , Zhaokui Wang

Image diffusion models are trained on independently sampled static images. While this is the bedrock task protocol in generative modeling, capturing the temporal world through the lens of static snapshots is information-deficient by design.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Juhun Lee , Simon S. Woo

Medical Image Synthesis (MIS) plays an important role in the intelligent medical field, which greatly saves the economic and time costs of medical diagnosis. However, due to the complexity of medical images and similar characteristics of…

Image and Video Processing · Electrical Eng. & Systems 2025-03-07 Zhihan Ju , Wanting Zhou , Longteng Kong , Yu Chen , Yi Li , Zhenan Sun , Caifeng Shan