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High-precision medical diagnosis relies not only on static imaging features but also on the implicit diagnostic memory experts instantly invoke during image interpretation. We pinpoint a fundamental cognitive misalignment in medical VLMs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Chunzheng Zhu , Jiaqi Zeng , Junyu Jiang , Jianxin Lin , Yijun Wang

Continual learning in medical image segmentation involves sequential data acquisition across diverse domains (e.g., clinical sites), where task interference between past and current domains often leads to catastrophic forgetting. Existing…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Yuxin Ye , Yan Liu , Shujian Yu

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang

Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tong Chen , Chao Cao , Yan Zhuang , Minheng Chen , Tianming Liu , Dajiang Zhu

An ensemble of trained multimodal encoders and vision-language models (VLMs) has become a standard approach for visual question answering (VQA) tasks. However, such models often fail to produce responses with the detailed precision…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Rakesh Raj Madavan , Akshat Kaimal , Hashim Faisal , Chandrakala S

Synthetic data, an appealing alternative to extensive expert-annotated data for medical image segmentation, consistently fails to improve segmentation performance despite its visual realism. The reason being that synthetic and real medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 OFM Riaz Rahman Aranya , Kevin Desai

Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

Accurate and robust medical image classification is paramount for early disease diagnosis and treatment planning. However, challenges such as limited annotated data, high intra-class variability, and subtle inter-class differences often…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Joao Florindo , Viviane Moura

Multi-modal pre-trained models efficiently extract and fuse features from different modalities with low memory requirements for fine-tuning. Despite this efficiency, their application in disease diagnosis is under-explored. A significant…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Zhiyi Shi , Junsik Kim , Wanhua Li , Yicong Li , Hanspeter Pfister

In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Chaoyi Wu , Xiaoman Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Fine-grained medical image classification is challenged by subtle inter-class variations and visually ambiguous cases, where confidence estimates often exhibit uncertainty rather than being overconfident. In such scenarios, purely…

Artificial Intelligence · Computer Science 2026-04-21 Zixuan Tang , Shen Zhao

In medical information extraction, medical Named Entity Recognition (NER) is indispensable, playing a crucial role in developing medical knowledge graphs, enhancing medical question-answering systems, and analyzing electronic medical…

Computation and Language · Computer Science 2024-03-26 Xiaojing Du , Hanjie Zhao , Danyan Xing , Yuxiang Jia , Hongying Zan

Multi-modal image registration plays a critical role in precision medicine but faces challenges from non-linear intensity relationships and local optima. While deep learning models enable rapid inference, they often suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

Despite the remarkable success of the end-to-end paradigm in deep learning, it often suffers from slow convergence and heavy reliance on large-scale datasets, which fundamentally limits its efficiency and applicability in data-scarce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Feifei Zhang , Zhenhong Jia , Sensen Song , Fei Shi , Dayong Ren

In this paper, we introduce a new vision-language pre-trained model -- ImageBERT -- for image-text joint embedding. Our model is a Transformer-based model, which takes different modalities as input and models the relationship between them.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Di Qi , Lin Su , Jia Song , Edward Cui , Taroon Bharti , Arun Sacheti

Aligning Large Language Models (LLMs) with high-stakes medical standards remains a significant challenge, primarily due to the dissonance between coarse-grained preference signals and the complex, multi-dimensional nature of clinical…

Artificial Intelligence · Computer Science 2026-04-10 He Geng , Yangmin Huang , Lixian Lai , Qianyun Du , Hui Chu , Zhiyang He , Jiaxue Hu , Xiaodong Tao

Multimodal embedding models, built upon causal Vision Language Models (VLMs), have shown promise in various tasks. However, current approaches face three key limitations: the use of causal attention in VLM backbones is suboptimal for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Haonan Chen , Hong Liu , Yuping Luo , Liang Wang , Nan Yang , Furu Wei , Zhicheng Dou

Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

Neurons and Cognition · Quantitative Biology 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby

Multimodal medical image fusion plays a crucial role in medical diagnosis by integrating complementary information from different modalities to enhance image readability and clinical applicability. However, existing methods mainly follow…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Haozhe Xiang , Han Zhang , Yu Cheng , Xiongwen Quan , Wanwan Huang

The early detection of mental health disorders from social media text is critical for enabling timely support, risk assessment, and referral to appropriate resources. This work introduces multiMentalRoBERTa, a fine-tuned RoBERTa model…

Computation and Language · Computer Science 2025-11-11 K M Sajjadul Islam , John Fields , Praveen Madiraju