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Modern AI algorithms require labeled data. In real world, majority of data are unlabeled. Labeling the data are costly. this is particularly true for some areas requiring special skills, such as reading radiology images by physicians. To…

Machine Learning · Statistics 2026-03-31 Yiran Huang , Jian-Feng Yang , Haoda Fu

In this study, we propose HOPER (HOlistic ProtEin Representation), a novel multimodal learning framework designed to enhance protein function prediction (PFP) in low-data settings. The challenge of predicting protein functions is compounded…

Biomolecules · Quantitative Biology 2024-12-18 Serbülent Ünsal , Sinem Özdemir , Bünyamin Kasap , M. Erşan Kalaycı , Kemal Turhan , Tunca Doğan , Aybar C. Acar

Existing test-time adaptation (TTA) approaches often adapt models with the unlabeled testing data stream. A recent attempt relaxed the assumption by introducing limited human annotation, referred to as Human-In-the-Loop Test-Time Adaptation…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Yushu Li , Yongyi Su , Xulei Yang , Kui Jia , Xun Xu

Deep learning-based human activity recognition (HAR) methods have shown great promise in the applications of smart healthcare systems and wireless body sensor network (BSN). Despite their demonstrated performance in laboratory settings, the…

Human-Computer Interaction · Computer Science 2023-03-28 Baichun Wei , Chunzhi Yi , Qi Zhang , Haiqi Zhu , Jianfei Zhu , Feng Jiang

A key challenge in enzyme annotation is identifying the biochemical reactions catalyzed by proteins. Most existing methods rely on Enzyme Commission (EC) numbers as intermediaries: they first predict an EC number and then retrieve the…

Machine Learning · Computer Science 2026-03-16 Zhenkun Shi , Jun Zhu , Dehang Wang , BoYu Chen , Qianqian Yuan , Zhitao Mao , Fan Wei , Weining Wu , Xiaoping Liao , Hongwu Ma

Sensor-based human activity recognition (HAR) requires to predict the action of a person based on sensor-generated time series data. HAR has attracted major interest in the past few years, thanks to the large number of applications enabled…

Machine Learning · Computer Science 2021-03-30 Davide Buffelli , Fabio Vandin

Protein mutations can have profound effects on biological function, making accurate prediction of property changes critical for drug discovery, protein engineering, and precision medicine. Current approaches rely on fine-tuning…

Machine Learning · Computer Science 2025-10-27 Srivathsan Badrinarayanan , Yue Su , Janghoon Ock , Alan Pham , Sanya Ahuja , Amir Barati Farimani

Various health-care applications such as assisted living, fall detection etc., require modeling of user behavior through Human Activity Recognition (HAR). HAR using mobile- and wearable-based deep learning algorithms have been on the rise…

Machine Learning · Computer Science 2019-06-04 Gautham Krishna Gudur , Prahalathan Sundaramoorthy , Venkatesh Umaashankar

How to accurately predict the properties of molecules is an essential problem in AI-driven drug discovery, which generally requires a large amount of annotation for training deep learning models. Annotating molecules, however, is quite…

Machine Learning · Computer Science 2022-05-24 Kuangqi Zhou , Kaixin Wang , Jiashi Feng , Jian Tang , Tingyang Xu , Xinchao Wang

Integrating human expertise into machine learning systems often reduces the role of experts to labeling oracles, a paradigm that limits the amount of information exchanged and fails to capture the nuances of human judgment. We address this…

Human-Computer Interaction · Computer Science 2026-02-18 Belén Martín-Urcelay , Yoonsang Lee , Matthieu R. Bloch , Christopher J. Rozell

Active Learning (AL) is a human-in-the-loop framework to interactively and adaptively label data instances, thereby enabling significant gains in model performance compared to random sampling. AL approaches function by selecting the hardest…

Machine Learning · Computer Science 2023-06-05 Nathan Beck , Krishnateja Killamsetty , Suraj Kothawade , Rishabh Iyer

Deep learning-based medical image segmentation models often face performance degradation when deployed across various medical centers, largely due to the discrepancies in data distribution. Test Time Adaptation (TTA) methods, which adapt…

Computer Vision and Pattern Recognition · Computer Science 2024-05-15 Shishuai Hu , Zehui Liao , Zeyou Liu , Yong Xia

Deep learning has proven to be an effective approach in the field of Human activity recognition (HAR), outperforming other architectures that require manual feature engineering. Despite recent advancements, challenges inherent to HAR data,…

Machine Learning · Computer Science 2023-07-18 Yiran Huang , Yexu Zhou , Till Riedel , Likun Fang , Michael Beigl

Enzyme engineering enables the modification of wild-type proteins to meet industrial and research demands by enhancing catalytic activity, stability, binding affinities, and other properties. The emergence of deep learning methods for…

Computation and Language · Computer Science 2024-10-29 Yang Tan , Ruilin Wang , Banghao Wu , Liang Hong , Bingxin Zhou

Wearable sensors in Internet of Things (IoT) ecosystems increasingly support applications such as remote health monitoring, elderly care, and smart home automation, all of which rely on robust human activity recognition (HAR). Continual…

In recent years, deep learning has emerged as a potent tool across a multitude of domains, leading to a surge in research pertaining to its application in the wearable human activity recognition (WHAR) domain. Despite the rapid development,…

Machine Learning · Computer Science 2024-01-12 Yiran Huang , Haibin Zhao , Yexu Zhou , Till Riedel , Michael Beigl

Automatic recognition of human activities from time-series sensor data (referred to as HAR) is a growing area of research in ubiquitous computing. Most recent research in the field adopts supervised deep learning paradigms to automate…

Machine Learning · Computer Science 2018-11-21 Alireza Abedin Varamin , Ehsan Abbasnejad , Qinfeng Shi , Damith Ranasinghe , Hamid Rezatofighi

Continual learning, also known as lifelong learning, is an emerging research topic that has been attracting increasing interest in the field of machine learning. With human activity recognition (HAR) playing a key role in enabling numerous…

Machine Learning · Computer Science 2022-11-18 Rebecca Adaimi , Edison Thomaz

Protein function annotation is an important yet challenging task in biology. Recent deep learning advancements show significant potential for accurate function prediction by learning from protein sequences and structures. Nevertheless,…

Biomolecules · Quantitative Biology 2024-02-14 Zuobai Zhang , Jiarui Lu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction…

Genomics · Quantitative Biology 2024-05-21 Jiayu Shang , Cheng Peng , Yongxin Ji , Jiaojiao Guan , Dehan Cai , Xubo Tang , Yanni Sun
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