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Whole slide images (WSIs) are vital in digital pathology, enabling gigapixel tissue analysis across various pathological tasks. While recent advancements in multi-modal large language models (MLLMs) allow multi-task WSI analysis through…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Xinheng Lyu , Yuci Liang , Wenting Chen , Meidan Ding , Jiaqi Yang , Guolin Huang , Daokun Zhang , Xiangjian He , Linlin Shen

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

Artificial Intelligence · Computer Science 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi

Recent advances in multi-modal large language models (MLLMs) have enabled increasingly sophisticated autonomous visualization agents capable of translating user intentions into data visualizations. However, measuring progress and comparing…

Human-Computer Interaction · Computer Science 2025-09-19 Kuangshi Ai , Haichao Miao , Zhimin Li , Chaoli Wang , Shusen Liu

Rare diseases, despite their low individual incidence, collectively impact around 300 million people worldwide due to the vast number of diseases. The involvement of multiple organs and systems, and the shortage of specialized doctors with…

Computation and Language · Computer Science 2025-11-11 Xuanzhong Chen , Ye Jin , Xiaohao Mao , Lun Wang , Shuyang Zhang , Ting Chen

Medical diagnosis prediction plays a critical role in disease detection and personalized healthcare. While machine learning (ML) models have been widely adopted for this task, their reliance on supervised training limits their ability to…

Artificial Intelligence · Computer Science 2025-07-08 Yuzhang Xie , Hejie Cui , Ziyang Zhang , Jiaying Lu , Kai Shu , Fadi Nahab , Xiao Hu , Carl Yang

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Accurate diagnosis of skin diseases remains a significant challenge due to the complex and diverse visual features present in dermatoscopic images, often compounded by a lack of interpretability in existing purely visual diagnostic models.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Kexin Yu , Zihan Xu , Jialei Xie , Carter Adams

Multi-agent large language model (LLM) systems have emerged as a promising approach for clinical diagnosis, leveraging collaboration among agents to refine medical reasoning. However, most existing frameworks rely on single-vendor teams…

Computation and Language · Computer Science 2026-03-17 Grace Chang Yuan , Xiaoman Zhang , Sung Eun Kim , Pranav Rajpurkar

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Katarina Trojachanec Dineva , Stefan Andonov , Ilinka Ivanoska , Ivan Kitanovski , Sasho Gramatikov , Tamara Kostova , Monika Simjanoska Misheva , Kostadin Mishev

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

Medical image diagnosis is challenging because many diseases resemble normal anatomy and exhibit substantial interpatient variability. Clinicians routinely rely on comparative diagnosis, such as referencing cross-patient healthy control…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Ruinan Jin , Gexin Huang , Xinwei Shen , Qiong Zhang , Yan Shuo Tan , Xiaoxiao Li

The rapid advancement of Large Language Models (LLMs) has stimulated interest in multi-agent collaboration for addressing complex medical tasks. However, the practical advantages of multi-agent collaboration approaches remain insufficiently…

Artificial Intelligence · Computer Science 2025-10-31 Yinghao Zhu , Ziyi He , Haoran Hu , Xiaochen Zheng , Xichen Zhang , Zixiang Wang , Junyi Gao , Liantao Ma , Lequan Yu

Decades' advances in digital health technologies, such as electronic health records, have largely streamlined routine clinical processes. Yet, most these systems are still hard to learn and use: Clinicians often face the burden of managing…

Artificial Intelligence · Computer Science 2025-09-16 Jared Zhu , Junde Wu

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Computation and Language · Computer Science 2024-07-12 Masoud Monajatipoor , Jiaxin Yang , Joel Stremmel , Melika Emami , Fazlolah Mohaghegh , Mozhdeh Rouhsedaghat , Kai-Wei Chang

Distracted driving is a major cause of traffic collisions, calling for robust and scalable detection methods. Vision-language models (VLMs) enable strong zero-shot image classification, but existing VLM-based distracted driver detectors…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Takamichi Miyata , Sumiko Miyata , Andrew Morris

To address the limitations of Large Language Models (LLMs) in the International Classification of Diseases (ICD) coding task, where they often produce inaccurate and incomplete prediction results due to the high-dimensional and skewed…

Computation and Language · Computer Science 2024-08-15 Rumeng Li , Xun Wang , Hong Yu

Pre-trained multi-modal vision-language models (VLMs) are becoming increasingly popular due to their exceptional performance on downstream vision applications, particularly in the few- and zero-shot settings. However, selecting the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Orr Zohar , Shih-Cheng Huang , Kuan-Chieh Wang , Serena Yeung

Identifying and articulating limitations is essential for transparent and rigorous scientific research. However, zero-shot large language models (LLMs) approach often produce superficial or general limitation statements (e.g., dataset bias…

Computation and Language · Computer Science 2026-03-17 Ibrahim Al Azher , Zhishuai Guo , Hamed Alhoori

Medical vision language pre-training (VLP) has emerged as a frontier of research, enabling zero-shot pathological recognition by comparing the query image with the textual descriptions for each disease. Due to the complex semantics of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Vu Minh Hieu Phan , Yutong Xie , Yuankai Qi , Lingqiao Liu , Liyang Liu , Bowen Zhang , Zhibin Liao , Qi Wu , Minh-Son To , Johan W. Verjans

Recently, Multimodal Large Language Models (MLLMs) have demonstrated exceptional capabilities in visual understanding and reasoning across various vision-language tasks. However, we found that MLLMs cannot process effectively from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Bangyan Li , Wenxuan Huang , Zhenkun Gao , Yeqiang Wang , Yunhang Shen , Jingzhong Lin , Ling You , Yuxiang Shen , Shaohui Lin , Wanli Ouyang , Yuling Sun
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