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It is often important to incorporating covariate information in the design of clinical trials. In literature, there are many designs of using stratification and covariate-adaptive randomization to balance on certain known covariate.…

Methodology · Statistics 2009-08-30 Li-Xin Zhang , Feifang Hu

Uncertainty quantification is essential in decision-making, especially when joint distributions of random variables are involved. While conformal prediction provides distribution-free prediction sets with valid coverage guarantees, it…

Machine Learning · Computer Science 2025-01-03 Rui Luo , Zhixin Zhou

Anomaly detection (AD) is the machine learning task of identifying highly discrepant abnormal samples by solely relying on the consistency of the normal training samples. Under the constraints of a distribution shift, the assumption that…

Machine Learning · Computer Science 2023-12-25 João B. S. Carvalho , Mengtao Zhang , Robin Geyer , Carlos Cotrini , Joachim M. Buhmann

Purpose: Covariate adjustment is a powerful statistical technique that can increase efficiency in clinical trials. Recent guidance from the U.S. FDA provided recommendations and best practices for using covariate adjustment. However, there…

We introduce an adaptive regularization approach. In contrast to conventional Tikhonov regularization, which specifies a fixed regularization operator, we estimate it simultaneously with parameters. From a Bayesian perspective we estimate…

Computer Vision and Pattern Recognition · Computer Science 2009-06-19 Andriy Myronenko , Xubo Song

Semiparametric regression offers a flexible framework for modeling non-linear relationships between a response and covariates. A prime example are generalized additive models where splines (say) are used to approximate non-linear functional…

Statistics Theory · Mathematics 2018-10-05 Francis K. C. Hui , Chong You , Han Lin Shang , Samuel Müller

In many applications such as rationing medical care and supplies, university admissions, and the assignment of public housing, the decision of who receives an allocation can be justified by various normative criteria. Such settings have…

Computer Science and Game Theory · Computer Science 2023-05-30 Siddhartha Banerjee , Matthew Eichhorn , David Kempe

Feature alignment methods are used in many scientific disciplines for data pooling, annotation, and comparison. As an instance of a permutation learning problem, feature alignment presents significant statistical and computational…

Statistics Theory · Mathematics 2023-11-23 Yanjun Han , Philippe Rigollet , George Stepaniants

The ability to generalize experimental results from randomized control trials (RCTs) across locations is crucial for informing policy decisions in targeted regions. Such generalization is often hindered by the lack of identifiability due to…

Econometrics · Economics 2021-12-10 Xinkun Nie , Guido Imbens , Stefan Wager

The adaptive Metropolis (AM) algorithm of Haario, Saksman and Tamminen [Bernoulli 7 (2001) 223-242] uses the estimated covariance of the target distribution in the proposal distribution. This paper introduces a new robust adaptive…

Computation · Statistics 2011-05-30 Matti Vihola

The problem of covariance estimation for replicated surface-valued processes is examined from the functional data analysis perspective. Considerations of statistical and computational efficiency often compel the use of separability of the…

Methodology · Statistics 2021-10-25 Tomas Masak , Victor M. Panaretos

In this paper, we propose a new feature selection method for unsupervised domain adaptation based on the emerging optimal transportation theory. We build upon a recent theoretical analysis of optimal transport in domain adaptation and show…

Machine Learning · Computer Science 2018-06-29 Léo Gautheron , Ievgen Redko , Carole Lartizien

Reliably characterizing the full conditional distribution of a multivariate response variable given a set of covariates is crucial for trustworthy decision-making. However, misspecified or miscalibrated multivariate models may yield a poor…

Machine Learning · Computer Science 2025-10-27 Victor Dheur , Souhaib Ben Taieb

In many real applications of statistical learning, collecting sufficiently many training data is often expensive, time-consuming, or even unrealistic. In this case, a transfer learning approach, which aims to leverage knowledge from a…

Machine Learning · Statistics 2025-02-26 Baozhen Wang , Xingye Qiao

Ascertaining causal direction from observational data is a fundamental challenge in scientific inquiry. Of particular interest is the problem of covariate-adjusted bivariate causal discovery, i.e., determining the causal direction between X…

Methodology · Statistics 2025-07-30 Soumik Purkayastha , Peter X. -K. Song

Ordering the expected outcomes across a collection of clusters after performing a covariate adjustment commonly arises in many applied settings, such as healthcare provider evaluation. Regression parameters in such covariate adjustment…

Methodology · Statistics 2025-11-21 Nicholas C. Henderson , Nicholas Hartman

Large-scale population-level datasets, such as the UK Biobank and the All of Us Research Program, often lack covariates needed for a specific analysis, such as genetic or lifestyle measures, while related studies measure them. This creates…

Methodology · Statistics 2026-05-07 Huali Zhao , Tianying Wang

Eliminating the covariate shift cross domains is one of the common methods to deal with the issue of domain shift in visual unsupervised domain adaptation. However, current alignment methods, especially the prototype based or sample-level…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Yin Zhao , Minquan Wang , Longjun Cai

Conformalized Quantile Regression (CQR) is a recently proposed method for constructing prediction intervals for a response $Y$ given covariates $X$, without making distributional assumptions. However, existing constructions of CQR can be…

Methodology · Statistics 2024-05-16 Raphael Rossellini , Rina Foygel Barber , Rebecca Willett

In clinical trials, there is potential to improve precision and reduce the required sample size by appropriately adjusting for baseline variables in the statistical analysis. This is called covariate adjustment. Despite recommendations by…

Methodology · Statistics 2022-06-20 Kelly Van Lancker , Joshua Betz , Michael Rosenblum
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