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Machine learning in medicine leverages the wealth of healthcare data to extract knowledge, facilitate clinical decision-making, and ultimately improve care delivery. However, ML models trained on datasets that lack demographic diversity…

Machine Learning · Computer Science 2021-11-19 Songzi Liu , Yuan Luo

Personalized computed tomography (CT) dosimetry has great potential in assessing patient-specific radiation exposure, supporting risk assessment, and optimizing clinical protocols. The aim of this study is to evaluate the potential of…

Medical Physics · Physics 2026-01-15 Marie-Luise Kuhlmann , Jörg Martin , Stefan Pojtinger

Chronic diseases such as diabetes are the leading causes of morbidity and mortality worldwide. Numerous research studies have been attempted with various deep learning models in diagnosis. However, most previous studies had certain…

Tabular data prediction has been employed in medical applications such as patient health risk prediction. However, existing methods usually revolve around the algorithm design while overlooking the significance of data engineering. Medical…

Machine Learning · Computer Science 2024-05-02 Zifeng Wang , Chufan Gao , Cao Xiao , Jimeng Sun

The primary objective of phase I cancer clinical trials is to evaluate the safety of a new experimental treatment and to find the maximum tolerated dose (MTD). We show that the MTD estimation problem can be regarded as a level set…

Machine Learning · Statistics 2025-04-15 Keiichiro Seno , Kota Matsui , Shogo Iwazaki , Yu Inatsu , Shion Takeno , Shigeyuki Matsui

Background: Survival prediction models are often less reliable in clinical groups with limited sample sizes or few outcome events. Target-only models may be unstable, whereas models from larger cohorts may transfer poorly when risk-factor…

Methodology · Statistics 2026-05-18 Junhan Yu , Yurui Chen , Juan Delgado-SanMartin , Dennis Wang , Hong Pan , Doudou Zhou

Many countries are now experiencing the third wave of the COVID-19 pandemic straining the healthcare resources with an acute shortage of hospital beds and ventilators for the critically ill patients. This situation is especially worse in…

The classification of electrocardiogram (ECG) plays a crucial role in the development of an automatic cardiovascular diagnostic system. However, considerable variances in ECG signals between individuals is a significant challenge. Changes…

Signal Processing · Electrical Eng. & Systems 2023-06-08 Md Niaz Imtiaz , Naimul Khan

Recent works have shown that deep neural networks can achieve super-human performance in a wide range of image classification tasks in the medical imaging domain. However, these works have primarily focused on classification accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-10 Gongbo Liang , Yu Zhang , Xiaoqin Wang , Nathan Jacobs

Cardiovascular diseases are widespread among patients with chronic noncommunicable diseases and are one of the leading causes of death, including in the working age. The article presents the relevance of the development and application of…

Machine Learning · Computer Science 2023-08-22 T. V. Afanasieva , A. P. Kuzlyakin , A. V. Komolov

Models with Conditional Moment Restrictions (CMRs) are popular in economics. These models involve finite and infinite dimensional parameters. The infinite dimensional components include conditional expectations, conditional choice…

Econometrics · Economics 2024-11-01 Facundo Argañaraz , Juan Carlos Escanciano

Purpose: To automate contrast phase classification in CT using organ-specific features extracted from a widely used segmentation tool with a lightweight decision tree classifier. Materials and Methods: This retrospective study utilized…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Xinya Wang , Ronald M. Summers , Zhiyong Lu

A high-risk pregnancy is a pregnancy complicated by factors that can adversely affect the outcomes of the mother or the infant. Health insurers use algorithms to identify members who would benefit from additional clinical support. This work…

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

Other Quantitative Biology · Quantitative Biology 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

We consider a real-world chemotherapy scheduling template design problem, where we cluster patient types into groups and find a representative time-slot duration for each group to accommodate all patient types assigned to that group, aiming…

Optimization and Control · Mathematics 2025-10-14 Qing Zhu , Xian Yu , Yu-Li Huang

Multimodal large language models (MLLMs) hold considerable promise for applications in healthcare. However, their deployment in safety-critical settings is hindered by two key limitations: (i) sensitivity to prompt design, and (ii) a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Anita Kriz , Elizabeth Laura Janes , Xing Shen , Tal Arbel

Early recognition of clinical deterioration (CD) has vital importance in patients' survival from exacerbation or death. Electronic health records (EHRs) data have been widely employed in Early Warning Scores (EWS) to measure CD risk in…

Repetitive laboratory testing unlikely to yield clinically useful information is a common practice that burdens patients and increases healthcare costs. Education and feedback interventions have limited success, while general test ordering…

Recently, methodology was presented to facilitate the incorporation of interim analyses in stepped-wedge (SW) cluster randomised trials (CRTs). Here, we extend this previous discussion. We detail how the stopping boundaries, allocation…

Methodology · Statistics 2018-03-28 Michael Grayling , David Robertson , James Wason , Adrian Mander