Related papers: CryoNet.Refine: A One-step Diffusion Model for Rap…
Cryo-electron microscopy is a revolutionary technique that can provide 3D density maps at near-atomic resolution. However, map validation is still an open issue in the field. Despite several efforts from the community, it is possible to…
The task of reassembly is a significant challenge across multiple domains, including archaeology, genomics, and molecular docking, requiring the precise placement and orientation of elements to reconstruct an original structure. In this…
Determining the 3D structures of biological molecules is a key problem for both biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising technique for structure estimation which relies heavily on computational methods to…
Generating accurate and stable long rollouts is a notorious challenge for time-dependent PDEs (Partial Differential Equations). Recently, motivated by the importance of high-frequency accuracy, a refiner model called PDERefiner utilizes…
Single-particle electron cryomicroscopy (cryo-EM) is an increasingly popular technique for elucidating the three-dimensional structure of proteins and other biologically significant complexes at near-atomic resolution. It is an imaging…
Cryo-electron microscopy (cryo-EM) allows for the high-resolution reconstruction of 3D structures of proteins and other biomolecules. Successful reconstruction of both shape and movement greatly helps understand the fundamental processes of…
The past decade's "cryoEM revolution" has produced exponential growth in high-resolution structural data through advances in cryogenic electron microscopy (cryoEM) and tomography (cryoET). Deep learning integration into structural…
In this paper, we introduce a denoising diffusion algorithm to discover microstructures with nonlinear fine-tuned properties. Denoising diffusion probabilistic models are generative models that use diffusion-based dynamics to gradually…
Boundary detection of irregular and translucent objects is an important problem with applications in medical imaging, environmental monitoring and manufacturing, where many of these applications are plagued with scarce labeled data and low…
Real-world image super-resolution (Real-ISR) must handle complex degradations and inherent reconstruction ambiguities. While generative models have improved perceptual quality, a key trade-off remains with computational cost. One-step…
Crystal-structure phase mapping is a core, long-standing challenge in materials science that requires identifying crystal structures, or mixtures thereof, in synthesized materials. Materials science experts excel at solving simple systems…
Structural dynamics of macromolecules is critical to their structural-function relationship. Cryogenic electron microscopy (CryoEM) provides snapshots of vitrified protein at different compositional and conformational states, and the…
Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method to resolve biological macromolecules. In a cryo-EM experiment, the microscope produces…
We propose a unified diffusion model-based correction and super-resolution method to enhance the fidelity and resolution of diverse low-quality data through a two-step pipeline. First, the correction step employs a novel enhanced stochastic…
Diffusion models have demonstrated impressive image synthesis performance, yet many UNet-based models are trained at certain fixed resolutions. Their quality tends to degrade when generating images at out-of-training resolutions. We trace…
In recent years, an abundance of new molecular structures have been elucidated using cryo-electron microscopy (cryo-EM), largely due to advances in hardware technology and data processing techniques. Owing to these new exciting…
In real-world scenarios, images captured often suffer from blurring, noise, and other forms of image degradation, and due to sensor limitations, people usually can only obtain low dynamic range images. To achieve high-quality images,…
Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…
Image restoration and enhancement are pivotal for numerous computer vision applications, yet unifying these tasks efficiently remains a significant challenge. Inspired by the iterative refinement capabilities of diffusion models, we propose…
Monocular depth estimation within the diffusion-denoising paradigm demonstrates impressive generalization ability but suffers from low inference speed. Recent methods adopt a single-step deterministic paradigm to improve inference…