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In recurrent survival analysis where the event of interest can occur multiple times for each subject, frailty models play a crucial role by capturing unobserved heterogeneity at the subject level within a population. Frailty models…

Methodology · Statistics 2024-10-30 Borna Bateni , Peyman Bateni , Bishwadeep Bhattacharyya , Devin Reeh

This paper presents an approach to expert-guided subgroup discovery. The main step of the subgroup discovery process, the induction of subgroup descriptions, is performed by a heuristic beam search algorithm, using a novel parametrized…

Artificial Intelligence · Computer Science 2011-06-24 D. Gamberger , N. Lavrac

The perspective of developing trustworthy AI for critical applications in science and engineering requires machine learning techniques that are capable of estimating their own uncertainty. In the context of regression, instead of estimating…

Machine Learning · Computer Science 2026-05-14 Quentin Duchemin , Guillaume Obozinski

In the era of precision medicine, time-to-event outcomes such as time to death or progression are routinely collected, along with high-throughput covariates. These high-dimensional data defy classical survival regression models, which are…

Methodology · Statistics 2025-07-15 Stephen Salerno , Yi Li

We introduce NeuralSurv, the first deep survival model to incorporate Bayesian uncertainty quantification. Our non-parametric, architecture-agnostic framework captures time-varying covariate-risk relationships in continuous time via a novel…

Machine Learning · Computer Science 2025-12-17 Mélodie Monod , Alessandro Micheli , Samir Bhatt

We consider a parametric modelling approach for survival data where covariates are allowed to enter the model through multiple distributional parameters, i.e., scale and shape. This is in contrast with the standard convention of having a…

Methodology · Statistics 2021-11-17 Fatima-Zahra Jaouimaa , Il Do Ha , Kevin Burke

Interpretable machine learning has emerged as central in leveraging artificial intelligence within high-stakes domains such as healthcare, where understanding the rationale behind model predictions is as critical as achieving high…

Machine Learning · Computer Science 2024-04-30 Christel Sirocchi , Martin Urschler , Bastian Pfeifer

We consider the problem in regression analysis of identifying subpopulations that exhibit different patterns of response, where each subpopulation requires a different underlying model. Unlike statistical cohorts, these subpopulations are…

Machine Learning · Statistics 2018-10-25 Alexander New , Curt Breneman , Kristin P. Bennett

Treatment specific survival curves are an important tool to illustrate the treatment effect in studies with time-to-event outcomes. In non-randomized studies, unadjusted estimates can lead to biased depictions due to confounding. Multiple…

Methodology · Statistics 2023-04-25 Robin Denz , Renate Klaaßen-Mielke , Nina Timmesfeld

We prove uniform consistency of Random Survival Forests (RSF), a newly introduced forest ensemble learner for analysis of right-censored survival data. Consistency is proven under general splitting rules, bootstrapping, and random selection…

Statistics Theory · Mathematics 2008-11-19 Hemant Ishwaran , Udaya B. Kogalur

Survival prediction with small sets of features is a highly relevant topic for decision-making in clinical practice. I describe a method for predicting survival of amyotrophic lateral sclerosis (ALS) patients that was developed as a…

Applications · Statistics 2016-12-05 Christoph Kurz

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

Machine Learning · Computer Science 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

Modern applications of machine learning (ML) deal with increasingly heterogeneous datasets comprised of data collected from overlapping latent subpopulations. As a result, traditional models trained over large datasets may fail to recognize…

Machine Learning · Statistics 2019-10-16 Benjamin Lengerich , Bryon Aragam , Eric P. Xing

In cancer epidemiology, the \emph{relative survival framework} is used to quantify the hazard associated with cancer by comparing the all-cause mortality hazard in cancer patients to that of the general population. This framework assumes…

Applications · Statistics 2024-11-05 Piyali Basak , Antonio R. Linero , Camille Maringe , F. Javier Rubio

Survival prediction often involves estimating the time-to-event distribution from censored datasets. Previous approaches have focused on enhancing discrimination and marginal calibration. In this paper, we highlight the significance of…

Machine Learning · Computer Science 2025-03-25 Shi-ang Qi , Yakun Yu , Russell Greiner

Usual parametric and semi-parametric regression methods are inappropriate and inadequate for large clustered survival studies when the appropriate functional forms of the covariates and their interactions in hazard functions are unknown,…

Methodology · Statistics 2024-11-12 Durbadal Ghosh , Debajyoti Sinha , Antonio R. Linero , George Rust

Health policy decisions are often informed by estimates of long-term survival based primarily on short-term data. A range of methods are available to include longer-term information, but there has previously been no comprehensive and…

Methodology · Statistics 2025-05-05 Christopher Jackson

Survival analysis stands as a pivotal process in cancer treatment research, crucial for predicting patient survival rates accurately. Recent advancements in data collection techniques have paved the way for enhancing survival predictions by…

Machine Learning · Computer Science 2024-07-26 Linhao Qu , Dan Huang , Shaoting Zhang , Xiaosong Wang

Survival is traditionally modeled as a supervised learning task, reliant on curated outcome labels and fixed covariates. This work rejects that premise. It proposes that survival is not an externally annotated target but a geometric…

Machine Learning · Computer Science 2025-08-12 Atahan Karagoz

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2016-11-15 Chris Roadknight , Uwe Aickelin , John Scholefield , Lindy Durrant
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