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We study the problem of understanding where two populations differ within a feature space, which we formalize in the concept of a differential subgroup: a subset of individuals from both populations who, despite sharing similar…

Machine Learning · Computer Science 2026-05-01 Sascha Xu , Jilles Vreeken

Survival analysis is a crucial semi-supervised task in machine learning with numerous real-world applications, particularly in healthcare. Currently, the most common approach to survival analysis is based on Cox's partial likelihood, which…

Machine Learning · Computer Science 2023-04-27 Andre Vauvelle , Benjamin Wild , Aylin Cakiroglu , Roland Eils , Spiros Denaxas

Survival analysis is widely used as a technique to model time-to-event data when some data is censored, particularly in healthcare for predicting future patient risk. In such settings, survival models must be both accurate and interpretable…

Machine Learning · Computer Science 2024-04-24 Mike Van Ness , Madeleine Udell

Accurate predictions of when a component will fail are crucial when planning maintenance, and by modeling the distribution of these failure times, survival models have shown to be particularly useful in this context. The presented…

Machine Learning · Computer Science 2024-03-28 Olov Holmer , Mattias Krysander , Erik Frisk

In epidemiological research, modeling the cumulative effects of time-dependent exposures on survival outcomes presents a challenge due to their intricate temporal dynamics. Conventional spline-based statistical methods, though effective,…

Machine Learning · Computer Science 2026-01-01 Kang-Chung Yang , Shinsheng Yuan

In this paper we propose a semi-supervised variational autoencoder for classification of overall survival groups from tumor segmentation masks. The model can use the output of any tumor segmentation algorithm, removing all assumptions on…

Computer Vision and Pattern Recognition · Computer Science 2020-11-18 Sveinn Pálsson , Stefano Cerri , Andrea Dittadi , Koen Van Leemput

Discovering subgroups with the maximum average treatment effect is crucial for targeted decision making in domains such as precision medicine, public policy, and education. While most prior work is formulated in the potential outcome…

Machine Learning · Computer Science 2025-11-26 Lincen Yang , Zhong Li , Matthijs van Leeuwen , Saber Salehkaleybar

Survival analysis aims at modeling the relationship between covariates and event occurrence with some untracked (censored) samples. In implementation, existing methods model the survival distribution with strong assumptions or in a discrete…

Machine Learning · Computer Science 2023-05-25 Yu Ling , Weimin Tan , Bo Yan

Survival analysis is an integral part of the statistical toolbox. However, while most domains of classical statistics have embraced deep learning, survival analysis only recently gained some minor attention from the deep learning community.…

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

Machine Learning · Computer Science 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

Survival analysis in the presence of multiple possible adverse events, i.e., competing risks, is a pervasive problem in many industries (healthcare, finance, etc.). Since only one event is typically observed, the incidence of an event of…

Machine Learning · Computer Science 2018-08-20 Anton Nemchenko , Trent Kyono , Mihaela Van Der Schaar

Decision trees are popular in survival analysis for their interpretability and ability to model complex relationships. Survival trees, which predict the timing of singular events using censored historical data, are typically built through…

Machine Learning · Computer Science 2025-11-24 Antonio Consolo , Edoardo Amaldi , Emilio Carrizosa

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

Machine Learning · Computer Science 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

Machine Learning · Computer Science 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

Accurately predicting the time of occurrence of an event of interest is a critical problem in longitudinal data analysis. One of the main challenges in this context is the presence of instances whose event outcomes become unobservable after…

Machine Learning · Computer Science 2017-12-26 Ping Wang , Yan Li , Chandan K. Reddy

Discrimination and calibration represent two important properties of survival analysis, with the former assessing the model's ability to accurately rank subjects and the latter evaluating the alignment of predicted outcomes with actual…

Machine Learning · Computer Science 2024-06-04 Shi-ang Qi , Yakun Yu , Russell Greiner

We describe a unified framework within which we can build survival models. The motivation for this work comes from a study on the prediction of relapse among breast cancer patients treated at the Curie Institute in Paris, France. Our focus…

Methodology · Statistics 2014-05-28 Cécile Chauvel , John O'Quigley

We propose a general approach for training survival analysis models that minimizes a worst-case error across all subpopulations that are large enough (occurring with at least a user-specified minimum probability). This approach uses a…

Machine Learning · Statistics 2022-11-22 Shu Hu , George H. Chen

Survival analysis is the branch of statistics that studies the relation between the characteristics of living entities and their respective survival times, taking into account the partial information held by censored cases. A good analysis…

Machine Learning · Computer Science 2023-03-07 Ammar Shaker , Carolin Lawrence

Flexible continuous-time survival modeling is critical for capturing complex time-varying hazard dynamics in high-dimensional data; however, training such models remains challenging due to the intractable integral required for likelihood…

Machine Learning · Statistics 2026-05-18 Chaeyeon Lee , Sehwan Kim , Hyungrok Do