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Recent advances in medical large language models (LLMs), multimodal models, and agents demand evaluation frameworks that reflect real clinical workflows and safety constraints. We present MedBench v4, a nationwide, cloud-based benchmarking…

Since the release of ChatGPT, the field of Natural Language Processing has experienced rapid advancements, particularly in Large Language Models (LLMs) and their multimodal counterparts, Large Multimodal Models (LMMs). Despite their…

Computation and Language · Computer Science 2024-08-27 Florian Schneider , Sunayana Sitaram

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Computation and Language · Computer Science 2025-03-21 Xiangru Tang , Daniel Shao , Jiwoong Sohn , Jiapeng Chen , Jiayi Zhang , Jinyu Xiang , Fang Wu , Yilun Zhao , Chenglin Wu , Wenqi Shi , Arman Cohan , Mark Gerstein

The rapid advancement of large language models (LLMs) has accelerated their integration into clinical decision support, particularly in prescription review. To enable systematic and fine-grained evaluation, we developed RxBench, a…

Computation and Language · Computer Science 2025-12-03 Yan Yang , Mouxiao Bian , Peiling Li , Bingjian Wen , Ruiyao Chen , Kangkun Mao , Xiaojun Ye , Tianbin Li , Pengcheng Chen , Bing Han , Jie Xu , Kaifeng Qiu , Junyan Wu

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

Computation and Language · Computer Science 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

Recently, multimodal large language models (MLLMs), such as GPT-4o, Gemini 1.5 Pro, and Reka Core, have expanded their capabilities to include vision and audio modalities. While these models demonstrate impressive performance across a wide…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Kaixiong Gong , Kaituo Feng , Bohao Li , Yibing Wang , Mofan Cheng , Shijia Yang , Jiaming Han , Benyou Wang , Yutong Bai , Zhuoran Yang , Xiangyu Yue

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Large language models perform well on static medical examinations, yet clinical diagnosis often requires iterative evidence gathering under uncertainty. Building on prior interactive evaluation efforts, we introduce an OSCE-inspired…

Artificial Intelligence · Computer Science 2026-05-22 Chen Zhan , Xihe Qiu , Xiaoyu Tan , Xibing Zhuang , Gengchen Ma , Yue Zhang , Shuo Li , Peifeng Liu , Xiaoxiao Ge , Liang Liu , Lu Gan

As large language models (LLMs) enter the medical domain, most benchmarks evaluate them on question answering or descriptive reasoning, overlooking quantitative reasoning critical to clinical decision-making. Existing datasets like…

Computation and Language · Computer Science 2025-11-03 Kangkun Mao , Jinru Ding , Jiayuan Chen , Mouxiao Bian , Ruiyao Chen , Xinwei Peng , Sijie Ren , Linyang Li , Jie Xu

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

Several studies showed that Large Language Models (LLMs) can answer medical questions correctly, even outperforming the average human score in some medical exams. However, to our knowledge, no study has been conducted to assess the ability…

Computation and Language · Computer Science 2025-01-03 Asma Ben Abacha , Wen-wai Yim , Yujuan Fu , Zhaoyi Sun , Meliha Yetisgen , Fei Xia , Thomas Lin

Large Language Models (LLMs) have shown impressive capabilities in generating human-like responses. However, their lack of domain-specific knowledge limits their applicability in healthcare settings, where contextual and comprehensive…

Computation and Language · Computer Science 2024-03-14 Subash Neupane , Shaswata Mitra , Sudip Mittal , Noorbakhsh Amiri Golilarz , Shahram Rahimi , Amin Amirlatifi

Multimodal large language models (MLLMs) are increasingly deployed in real-world, agentic settings where outputs must not only be correct, but also conform to predefined data schemas. Despite recent progress in structured generation in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Di Feng , Kaixin Ma , Feng Nan , Haofeng Chen , Bohan Zhai , David Griffiths , Mingfei Gao , Zhe Gan , Eshan Verma , Yinfei Yang , Zhifeng Chen , Afshin Dehghan

Large Language Models (LLMs) have exhibited exceptional performance in software engineering yet face challenges in adapting to continually evolving code knowledge, particularly regarding the frequent updates of third-party library APIs.…

Computation and Language · Computer Science 2025-06-19 Chenlong Wang , Zhaoyang Chu , Zhengxiang Cheng , Xuyi Yang , Kaiyue Qiu , Yao Wan , Zhou Zhao , Xuanhua Shi , Dongping Chen

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

Evaluating the nuanced human-centric video understanding capabilities of Multimodal Large Language Models (MLLMs) remains a great challenge, as existing benchmarks often overlook the intricacies of emotion, behavior, and cross-modal…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ting Zhou , Daoyuan Chen , Qirui Jiao , Bolin Ding , Yaliang Li , Ying Shen

The rapid integration of Large Vision-Language Models (LVLMs) into critical domains necessitates comprehensive moral evaluation to ensure their alignment with human values. While extensive research has addressed moral evaluation in LLMs,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Bei Yan , Jie Zhang , Zhiyuan Chen , Shiguang Shan , Xilin Chen

While Vision-Language Models (VLMs) and Multimodal Large Language Models (MLLMs) have shown strong generalisation in detecting image and video deepfakes, their use for audio deepfake detection remains largely unexplored. In this work, we…

Sound · Computer Science 2026-01-05 Akanksha Chuchra , Shukesh Reddy , Sudeepta Mishra , Abhijit Das , Abhinav Dhall

While Multimodal Large Language Models (MLLMs) excel at many vision tasks, it is unknown if they exhibit human-like perceptual behaviors. To evaluate this, we introduce HVSBench, the first large-scale benchmark with over 85,000 samples…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Jiaying Lin , Shuquan Ye , Dan Xu , Wanli Ouyang , Rynson W. H. Lau