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Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This…

Human-Computer Interaction · Computer Science 2025-11-12 Ivan Sviridov , Amina Miftakhova , Artemiy Tereshchenko , Galina Zubkova , Pavel Blinov , Andrey Savchenko

This paper proposes one of the first clinical applications of multimodal large language models (LLMs) as an assistant for radiologists to check errors in their reports. We created an evaluation dataset from real-world radiology datasets…

Computation and Language · Computer Science 2024-03-05 Jinge Wu , Yunsoo Kim , Eva C. Keller , Jamie Chow , Adam P. Levine , Nikolas Pontikos , Zina Ibrahim , Paul Taylor , Michelle C. Williams , Honghan Wu

The significant breakthroughs of Medical Multi-Modal Large Language Models (Med-MLLMs) renovate modern healthcare with robust information synthesis and medical decision support. However, these models are often evaluated on benchmarks that…

Computation and Language · Computer Science 2024-12-02 Jie Liu , Wenxuan Wang , Yihang Su , Jingyuan Huan , Wenting Chen , Yudi Zhang , Cheng-Yi Li , Kao-Jung Chang , Xiaohan Xin , Linlin Shen , Michael R. Lyu

Large language model (LLM)-based agents are increasingly used to solve complex tasks involving tool use, such as web browsing, code execution, and data analysis. However, current evaluation benchmarks do not adequately assess their ability…

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…

Computation and Language · Computer Science 2026-04-16 Zhijie Bao , Fangke Chen , Licheng Bao , Chenhui Zhang , Wei Chen , Jiajie Peng , Zhongyu Wei

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Despite impressive performance on standard benchmarks, multimodal large language models (MLLMs) face critical challenges in real-world clinical environments where medical images inevitably suffer various quality degradations. Existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Jiyao Liu , Junzhi Ning , Chenglong Ma , Wanying Qu , Jianghan Shen , Siqi Luo , Jinjie Wei , Jin Ye , Pengze Li , Tianbin Li , Jiashi Lin , Hongming Shan , Xinzhe Luo , Xiaohong Liu , Lihao Liu , Junjun He , Ningsheng Xu

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

Multimodal Large Language Models (MLLMs) have advanced in integrating diverse modalities but frequently suffer from hallucination. A promising solution to mitigate this issue is to generate text with citations, providing a transparent chain…

Computation and Language · Computer Science 2025-05-21 Caiyu Hu , Yikai Zhang , Tinghui Zhu , Yiwei Ye , Yanghua Xiao

While multimodal large language models (MLLMs) have made significant strides in natural image understanding, their ability to perceive and reason over hyperspectral image (HSI) remains underexplored, which is a vital modality in remote…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Xinyu Zhang , Zurong Mai , Qingmei Li , Zjin Liao , Yibin Wen , Yuhang Chen , Xiaoya Fan , Chan Tsz Ho , Bi Tianyuan , Haoyuan Liang , Ruifeng Su , Zihao Qian , Juepeng Zheng , Jianxi Huang , Yutong Lu , Haohuan Fu

Multimodal Large Language Models (MLLMs) have achieved significant advances in integrating visual and linguistic information, yet their ability to reason about complex and real-world scenarios remains limited. The existing benchmarks are…

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Dingyu Wang , Zimu Yuan , Jiajun Liu , Shanggui Liu , Nan Zhou , Tianxing Xu , Di Huang , Dong Jiang

Numerous advanced Large Language Models (LLMs) now support context lengths up to 128K, and some extend to 200K. Some benchmarks in the generic domain have also followed up on evaluating long-context capabilities. In the medical domain,…

Computation and Language · Computer Science 2024-06-24 Yongqi Fan , Hongli Sun , Kui Xue , Xiaofan Zhang , Shaoting Zhang , Tong Ruan

Large language models (LLMs) hold great promise for medical applications and are evolving rapidly, with new models being released at an accelerated pace. However, benchmarking on large-scale real-world data such as electronic health records…

Built on the power of LLMs, numerous multimodal large language models (MLLMs) have recently achieved remarkable performance on various vision-language tasks. However, most existing MLLMs and benchmarks primarily focus on single-image input…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Haowei Liu , Xi Zhang , Haiyang Xu , Yaya Shi , Chaoya Jiang , Ming Yan , Ji Zhang , Fei Huang , Chunfeng Yuan , Bing Li , Weiming Hu

Recently, large models have shown significant potential for smart healthcare. However, the deployment of Large Vision-Language Models (LVLMs) for clinical services is currently hindered by three critical challenges: a tendency to…

Artificial Intelligence · Computer Science 2025-10-27 Siyong Chen , Jinbo Wen , Jiawen Kang , Tenghui Huang , Xumin Huang , Yuanjia Su , Hudan Pan , Zishao Zhong , Dusit Niyato , Shengli Xie , Dong In Kim

Recent advancements in Large Multimodal Models (LMMs) have significantly improved multimodal understanding and generation. However, these models still struggle to generate tightly interleaved image-text outputs, primarily due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yukang Feng , Jianwen Sun , Chuanhao Li , Zizhen Li , Jiaxin Ai , Fanrui Zhang , Yifan Chang , Sizhuo Zhou , Shenglin Zhang , Yu Dai , Kaipeng Zhang

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler