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We apply multiple testing procedures to the validation of estimated default probabilities in credit rating systems. The goal is to identify rating classes for which the probability of default is estimated inaccurately, while still…

Applications · Statistics 2010-06-28 Sebastian Döhler

Machine learning predictions are increasingly used to supplement incomplete or costly-to-measure outcomes in fields such as biomedical research, environmental science, and social science. However, treating predictions as ground truth…

Machine Learning · Statistics 2026-01-29 Yilin Song , Dan M. Kluger , Harsh Parikh , Tian Gu

Public data repositories have enabled researchers to compare results across multiple genomic studies in order to replicate findings. A common approach is to first rank genes according to an hypothesis of interest within each study. Then,…

Applications · Statistics 2012-06-29 Loki Natarajan , Minya Pu , Karen Messer

We present a novel framework addressing a critical vulnerability in Large Language Models (LLMs): the prevalence of factual inaccuracies within intermediate reasoning steps despite correct final answers. This phenomenon poses substantial…

Computation and Language · Computer Science 2025-08-05 Rui Jiao , Yue Zhang , Jinku Li

In an attempt to provide an answer to the increasing criticism against p-values and to bridge the gap between statistical inference and prediction modelling, we introduce the probability of improved prediction (PIP). In general, the PIP is…

Methodology · Statistics 2024-05-28 Olivier Thas , Stijn Jaspers

Errors in implicative theories coming from binary data are studied. First, two classes of errors that may affect implicative theories are singled out. Two approaches for finding errors of these classes are proposed, both of them based on…

Artificial Intelligence · Computer Science 2014-10-21 Sergei O. Kuznetsov , Artem Revenko

Recent research has generated hope that inference scaling, such as resampling solutions until they pass verifiers like unit tests, could allow weaker models to match stronger ones. Beyond inference, this approach also enables training…

Machine Learning · Computer Science 2026-03-27 Benedikt Stroebl , Sayash Kapoor , Arvind Narayanan

The prevalence of machine learning in biomedical research is rapidly growing, yet the trustworthiness of such research is often overlooked. While some previous works have investigated the ability of adversarial attacks to degrade model…

Machine Learning · Statistics 2023-08-21 Matthew Rosenblatt , Javid Dadashkarimi , Dustin Scheinost

Imputation procedures in biomedical fields have turned into statistical practice, since further analyses can be conducted ignoring the former presence of missing values. In particular, non-parametric imputation schemes like the random…

Applications · Statistics 2018-08-13 Burim Ramosaj , Lubna Amro , Markus Pauly

We develop non-asymptotically justified methods for hypothesis testing about the $p-$dimensional coefficients $\theta^{*}$ in (possibly nonlinear) regression models. Given a function $h:\,\mathbb{R}^{p}\mapsto\mathbb{R}^{m}$, we consider…

Statistics Theory · Mathematics 2019-07-01 Ying Zhu

Compared to p-values, e-values provably guarantee safe, valid inference. If the goal is to test multiple hypotheses simultaneously, one can construct e-values for each individual test and then use the recently developed e-BH procedure to…

Methodology · Statistics 2024-12-03 Neil Dey , Ryan Martin , Jonathan P. Williams

Industrial control systems (ICS) of critical infrastructure are increasingly connected to the Internet for remote site management at scale. However, cyber attacks against ICS - especially at the communication channels between humanmachine…

Cryptography and Security · Computer Science 2021-01-29 Taejun Choi , Guangdong Bai , Ryan K L Ko , Naipeng Dong , Wenlu Zhang , Shunyao Wang

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

The partial conjunction null hypothesis is tested in order to discover a signal that is present in multiple studies. The standard approach of carrying out a multiple test procedure on the partial conjunction (PC) $p$-values can be extremely…

Methodology · Statistics 2024-06-14 Thorsten Dickhaus , Ruth Heller , Anh-Tuan Hoang , Yosef Rinott

Post-hoc calibration methods are widely used to improve the reliability of probabilistic predictions from machine learning models. Despite their prevalence, a comprehensive theoretical understanding of these methods remains elusive,…

Machine Learning · Computer Science 2025-09-30 Kristina P. Sinaga , Arjun S. Nair

In multiple testing several criteria to control for type I errors exist. The false discovery rate, which evaluates the expected proportion of false discoveries among the rejected null hypotheses, has become the standard approach in this…

Methodology · Statistics 2023-11-03 Jacobo de Uña-Álvarez

In a recent opinion article, Muff et al. recapitulate well-known objections to the Neyman-Pearson Null-Hypothesis Significance Testing (NHST) framework and call for reforming our practices in statistical reporting. We agree with them on…

Quantitative Methods · Quantitative Biology 2022-05-30 Florian Hartig , Frédéric Barraquand

We propose a method for multiple hypothesis testing with familywise error rate (FWER) control, called the i-FWER test. Most testing methods are predefined algorithms that do not allow modifications after observing the data. However, in…

Methodology · Statistics 2021-04-20 Boyan Duan , Aaditya Ramdas , Larry Wasserman

We explore the theoretical foundations of a ``twenty questions'' approach to pattern recognition. The object of the analysis is the computational process itself rather than probability distributions (Bayesian inference) or decision…

Statistics Theory · Mathematics 2007-06-13 Gilles Blanchard , Donald Geman

I present a critique of the methods used in a typical paper. This leads to three broad conclusions about the conventional use of statistical methods. First, results are often reported in an unnecessarily obscure manner. Second, the null…

Applications · Statistics 2013-03-05 Michael Wood