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Integrating theoretical neuroscience, decision theory, and probabilistic inference offers a promising route to understanding human cognition, yet concrete methodological bridges between agentic AI models and behavioral data analysis remain…

Neurons and Cognition · Quantitative Biology 2026-05-01 Dirk Ostwald , Rasmus Bruckner , Franziska Usée , Belinda Fleischmann , Joram Soch , Sean Mulready

Scientific Machine Learning (SciML) is concerned with the development of learned emulators of physical systems governed by partial differential equations (PDE). In application domains such as weather forecasting, molecular dynamics, and…

Machine Learning · Computer Science 2023-07-24 Makoto Takamoto , Francesco Alesiani , Mathias Niepert

Agent-based modelling (ABMing) is a powerful and intuitive approach to modelling complex systems; however, the intractability of ABMs' likelihood functions and the non-differentiability of the mathematical operations comprising these models…

Multiagent Systems · Computer Science 2023-05-25 Arnau Quera-Bofarull , Ayush Chopra , Anisoara Calinescu , Michael Wooldridge , Joel Dyer

Many real-world processes can naturally be modeled as systems of interacting agents. However, the long-term simulation of such agent-based models is often intractable when the system becomes too large. In this paper, starting from a…

Many emerging pathogens infect multiple host species, and multi-host pathogens may have very different dynamics in different host species. This research addresses how pathogen replication rates and Immune System (IS) response times are…

Other Quantitative Biology · Quantitative Biology 2009-10-19 Soumya Banerjee , Melanie Moses

Assessing acute brain dysfunction (ABD), including delirium and coma in the intensive care unit (ICU), is a critical challenge due to its prevalence and severe implications for patient outcomes. Current diagnostic methods rely on infrequent…

The COVID-19 pandemic prompted a surge in computational models to simulate disease dynamics and guide interventions. Agent-based models (ABMs) are well-suited to capture population and environmental heterogeneity, but their rapid deployment…

Complex dynamic systems are typically either modeled using expert knowledge in the form of differential equations or via data-driven universal approximation models such as artificial neural networks (ANN). While the first approach has…

Optimization and Control · Mathematics 2024-09-09 Christoph Plate , Carl Julius Martensen , Sebastian Sager

Agent-based models (ABMs) stand as an essential paradigm for proposing and validating hypothetical solutions or policies aimed at addressing challenges posed by complex systems and achieving various objectives. This process demands…

Computation and Language · Computer Science 2024-04-02 Tong Niu , Weihao Zhang , Rong Zhao

ML models in healthcare are typically evaluated using curated real-world EHR data. A key limitation of such evaluations is that they may fail to assess the robustness of ML models to changes in the data at deployment, which is a common…

Machine Learning · Computer Science 2026-05-12 Roben Delos Reyes , Daniel Capurro , Nicholas Geard

This paper introduces a hybrid attention and autoencoder (AE) model for unsupervised online anomaly detection in time series. The autoencoder captures local structural patterns in short embeddings, while the attention model learns long-term…

Machine Learning · Computer Science 2024-01-09 Seyed Amirhossein Najafi , Mohammad Hassan Asemani , Peyman Setoodeh

Many real-world systems are modelled using complex ordinary differential equations (ODEs). However, the dimensionality of these systems can make them challenging to analyze. Dimensionality reduction techniques like Proper Orthogonal…

Computational Engineering, Finance, and Science · Computer Science 2025-02-26 Abhishek Ajayakumar , Soumyendu Raha

Neural surrogates for Partial Differential Equations (PDEs) often suffer significant performance degradation when evaluated on problem configurations outside their training distribution, such as new initial conditions or structural…

Machine Learning · Computer Science 2026-02-11 Paul Setinek , Gianluca Galletti , Thomas Gross , Dominik Schnürer , Johannes Brandstetter , Werner Zellinger

This article extends the preprint "Characterizing Agent-Based Model Dynamics via $\epsilon$-Machines and Kolmogorov-Style Complexity" by introducing diffusion models as orthogonal and complementary tools for characterizing the output of…

Multiagent Systems · Computer Science 2025-12-05 Roberto Garrone

Calibrating Agent-Based Models (ABMs) is an important optimization problem for simulating the complex social systems, where the goal is to identify the optimal parameter of a given ABM by minimizing the discrepancy between the simulated…

Neural and Evolutionary Computing · Computer Science 2026-01-13 Boquan Jiang , Zhenhua Yang , Chenkai Wang , Muyao Zhong , Heping Fang , Peng Yang

Foundation models have recently extended beyond natural language and vision to timeseries domains, including physiological signals. However, progress in electrodermal activity (EDA) modeling is hindered by the absence of large-scale,…

Agent-based models (ABMs) are proliferating as decision-making tools across policy areas in transportation, economics, and epidemiology. In these models, a central object of interest is the discrete origin-destination matrix which captures…

Machine Learning · Computer Science 2025-05-12 Ioannis Zachos , Mark Girolami , Theodoros Damoulas

A family of explicit modified Euler methods (MEMs) is constructed for long-time approximations of super-linear SODEs driven by multiplicative noise. The proposed schemes can preserve the same Lyapunov structure as the continuous problems.…

Numerical Analysis · Mathematics 2025-09-11 Zhihui Liu , Xiaojie Wang , Xiaoming Wu , Xiaoyan Zhang

Parameter estimation and associated uncertainty quantification is an important problem in dynamical systems characterized by ordinary differential equation (ODE) models that are often nonlinear. Typically, such models have analytically…

Computation · Statistics 2024-03-26 Wai Meng Kwok , Sarat Chandra Dass , George Streftaris

Agent-Based Models are very useful for simulation of physical or social processes, such as the spreading of a pandemic in a city. Such models proceed by specifying the behavior of individuals (agents) and their interactions, and…

Multiagent Systems · Computer Science 2023-01-31 Varun Madhavan , Adway Mitra , Partha Pratim Chakrabarti