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The CDC Vaccine Safety Datalink project has pioneered the use of near real-time post-market vaccine safety surveillance for the rapid detection of adverse events. Doing weekly analyses, continuous sequential methods are used, allowing…

Applications · Statistics 2015-03-09 Martin Kulldorff , Ivair R. Silva

This paper considers the detection of change points in parallel data streams, a problem widely encountered when analyzing large-scale real-time streaming data. Each stream may have its own change point, at which its data has a…

Methodology · Statistics 2023-01-18 Zexian Lu , Yunxiao Chen , Xiaoou Li

We consider sequential maximization of performance metrics that are general functions of a confusion matrix of a classifier (such as precision, F-measure, or G-mean). Such metrics are, in general, non-decomposable over individual instances,…

Machine Learning · Computer Science 2024-06-24 Wojciech Kotłowski , Marek Wydmuch , Erik Schultheis , Rohit Babbar , Krzysztof Dembczyński

We propose a new framework for online testing of heterogeneous treatment effects. The proposed test, named sequential score test (SST), is able to control type I error under continuous monitoring and detect multi-dimensional heterogeneous…

Methodology · Statistics 2020-02-11 Miao Yu , Wenbin Lu , Rui Song

We revisit the problem of statistical sequence matching initiated by Unnikrishnan (TIT 2015) and derive theoretical performance guarantees for sequential tests that have bounded expected stopping times. Specifically, in this problem, one is…

Information Theory · Computer Science 2025-06-05 Lin Zhou , Qianyun Wang , Yun Wei , Jingjing Wang

A sequential multiple assignment randomized trial (SMART) facilitates comparison of multiple adaptive treatment strategies (ATSs) simultaneously. Previous studies have established a framework to test the homogeneity of multiple ATSs by a…

Methodology · Statistics 2022-11-04 Liwen Wu , Junyao Wang , Abdus S. Wahed

Verification is crucial for effective mathematical reasoning. We present a new temporal consistency method where verifiers iteratively refine their judgments based on the previous assessment. Unlike one-round verification or multi-model…

Computation and Language · Computer Science 2025-12-01 Jiacheng Guo , Yue Wu , Jiahao Qiu , Kaixuan Huang , Xinzhe Juan , Ling Yang , Mengdi Wang

Hierarchical inference in (generalized) regression problems is powerful for finding significant groups or even single covariates, especially in high-dimensional settings where identifiability of the entire regression parameter vector may be…

Methodology · Statistics 2021-10-22 Claude Renaux , Peter Bühlmann

Correlated observations are ubiquitous phenomena in a plethora of scientific avenues. Tackling this dependence among test statistics has been one of the pertinent problems in simultaneous inference. However, very little literature exists…

Statistics Theory · Mathematics 2024-11-20 Monitirtha Dey

We design sequential tests for a large class of nonparametric null hypotheses based on elicitable and identifiable functionals. Such functionals are defined in terms of scoring functions and identification functions, which are ideal…

Statistics Theory · Mathematics 2023-06-06 Philippe Casgrain , Martin Larsson , Johanna Ziegel

Responsibly deploying artificial intelligence (AI) / machine learning (ML) systems in high-stakes settings arguably requires not only proof of system reliability, but also continual, post-deployment monitoring to quickly detect and address…

Machine Learning · Computer Science 2025-08-26 Drew Prinster , Xing Han , Anqi Liu , Suchi Saria

A major bottleneck in characterizing the failure modes of generative AI systems is the cost and time of annotation and evaluation. Consequently, adaptive testing paradigms have gained popularity, where one opportunistically decides which…

Artificial Intelligence · Computer Science 2026-05-11 Siyu Zhou , Patrick Vossler , Venkatesh Sivaraman , Yifan Mai , Jean Feng

We introduce a novel segmental-attention model for automatic speech recognition. We restrict the decoder attention to segments to avoid quadratic runtime of global attention, better generalize to long sequences, and eventually enable…

Computation and Language · Computer Science 2022-10-27 Albert Zeyer , Robin Schmitt , Wei Zhou , Ralf Schlüter , Hermann Ney

We study sequential testing for a binary disease outcome when risk follows an unknown logistic model. At each round, the decision maker may either pay for a test revealing the true label or predict the outcome based on patient features and…

Machine Learning · Computer Science 2026-05-05 Tavor Z. Baharav , Spyros Dragazis , Aldo Pacchiano

In this paper we deal with the problem of sequential testing of multiple hypotheses. The main goal is minimizing the expected sample size (ESS) under restrictions on the error probabilities. We take, as a criterion of minimization, a…

Methodology · Statistics 2023-04-14 Andrey Novikov

This paper considers the change-point problem for finite sequences of networks. To avoid the difficulty of computing the normalization coefficient, such as in Exponential random graphical models (ERGMs) and Markov networks, we construct a…

Statistics Theory · Mathematics 2021-01-19 Lei Qiao , Dong Han

Post-approval safety surveillance of medical products using observational healthcare data can help identify safety issues beyond those found in pre-approval trials. When testing sequentially as data accrue, maximum sequential probability…

Methodology · Statistics 2022-07-07 Martijn J. Schuemie , Fan Bu , Akihiko Nishimura , Marc A. Suchard

State discrimination is a useful test problem with which to clarify the power and limitations of different classes of measurement. We consider the problem of discriminating between given states of a bi-partite quantum system via sequential…

Quantum Physics · Physics 2017-09-25 Sarah Croke , Stephen M. Barnett , Graeme Weir

Process monitoring and control requires detection of structural changes in a data stream in real time. This article introduces an efficient sequential Monte Carlo algorithm designed for learning unknown changepoints in continuous time. The…

Applications · Statistics 2015-09-29 Melissa J. M. Turcotte , Nicholas A. Heard

Decentralized learning provides a scalable alternative to parameter-server-based training, yet its performance is often hindered by limited peer-to-peer communication. In this paper, we study how communication should be scheduled over time,…

Machine Learning · Computer Science 2026-04-28 Tongtian Zhu , Tianyu Zhang , Mingze Wang , Zhanpeng Zhou , Can Wang
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