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Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

Image and Video Processing · Electrical Eng. & Systems 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen

Positron emission tomography (PET) is a widely used, highly sensitive molecular imaging in clinical diagnosis. There is interest in reducing the radiation exposure from PET but also maintaining adequate image quality. Recent methods using…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yuxin Xue , Lei Bi , Yige Peng , Michael Fulham , David Dagan Feng , Jinman Kim

Positron emission tomography (PET) offers powerful functional imaging but involves radiation exposure. Efforts to reduce this exposure by lowering the radiotracer dose or scan time can degrade image quality. While using magnetic resonance…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Yingkai Zhang , Shuang Chen , Ye Tian , Yunyi Gao , Jianyong Jiang , Ying Fu

Robust urban autonomous driving requires reliable 3D scene understanding and stable decision-making under dense interactions. However, existing end-to-end models lack interpretability, while modular pipelines suffer from error propagation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Guangli Chen , Dianzhao Li , Wenjian Zhong , Bangquan Xie , Ostap Okhrin

Given the inherent non-stationarity prevalent in real-world applications, continual Reinforcement Learning (RL) aims to equip the agent with the capability to address a series of sequentially presented decision-making tasks. Within this…

Machine Learning · Computer Science 2024-11-19 Feng Chen , Fuguang Han , Cong Guan , Lei Yuan , Zhilong Zhang , Yang Yu , Zongzhang Zhang

Purpose: Magnetic resonance imaging (MRI) exams include multiple series with varying contrast and redundant information. For instance, T2-FLAIR contrast is based upon tissue T2 decay and the presence of water, also present in T2- and…

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

This work presents TV-LoRA, a novel method for low-dose sparse-view CT reconstruction that combines a diffusion generative prior (NCSN++ with SDE modeling) and multi-regularization constraints, including anisotropic TV and nuclear norm…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Zongyin Deng , Qing Zhou , Yuhao Fang , Zijian Wang , Yao Lu , Ye Zhang , Chun Li

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Diffusion models excel at modeling complex data distributions, including those of images, proteins, and small molecules. However, in many cases, our goal is to model parts of the distribution that maximize certain properties: for example,…

RNA inverse folding, designing sequences to form specific 3D structures, is critical for therapeutics, gene regulation, and synthetic biology. Current methods, focused on sequence recovery, struggle to address structural objectives like…

Machine Learning · Computer Science 2026-01-28 Qi Si , Xuyang Liu , Penglei Wang , Xin Guo , Yuan Qi , Yuan Cheng

In recent years, Diffusion Models have become the new state-of-the-art in deep generative modeling, ending the long-time dominance of Generative Adversarial Networks. Inspired by the Regularization by Denoising principle, we introduce an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Pasquale Cascarano , Lorenzo Stacchio , Andrea Sebastiani , Alessandro Benfenati , Ulugbek S. Kamilov , Gustavo Marfia

While Generative Adversarial Nets (GANs) and Diffusion Models (DMs) have achieved impressive results in natural image synthesis, their core strengths - creativity and realism - can be detrimental in medical applications, where accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Sebastian Rassmann , David Kügler , Christian Ewert , Martin Reuter

Diffusion-based sparse-view CT (SVCT) imaging has achieved remarkable advancements in recent years, thanks to its more stable generative capability. However, recovering reliable image content and visually consistent textures is still a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Tianqi Wang , Wenchao Du , Hongyu Yang

Magnetic Resonance Angiography (MRA) has become an essential MR contrast for imaging and evaluation of vascular anatomy and related diseases. MRA acquisitions are typically ordered for vascular interventions, whereas in typical scenarios,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Sahin Olut , Yusuf Huseyin Sahin , Ugur Demir , Gozde Unal

Predicting drug-target affinity is fundamental to virtual screening and lead optimization. However, existing deep models often suffer from representation collapse in stringent cold-start regimes, where the scarcity of labels and domain…

Machine Learning · Statistics 2026-03-13 Yining Qian , Pengjie Wang , Yixiao Li , An-Yang Lu , Cheng Tan , Shuang Li , Lijun Liu

Diffusion prior-based methods have shown impressive results in real-world image super-resolution (SR). However, most existing methods entangle pixel-level and semantic-level SR objectives in the training process, struggling to balance…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Lingchen Sun , Rongyuan Wu , Zhiyuan Ma , Shuaizheng Liu , Qiaosi Yi , Lei Zhang

The adoption of text-to-image diffusion models raises concerns over reliability, drawing scrutiny under the lens of various metrics like calibration, fairness, or compute efficiency. We focus in this work on two issues that arise when…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Michael Kirchhof , James Thornton , Louis Béthune , Pierre Ablin , Eugene Ndiaye , Marco Cuturi

Generative recommendation represents each item as a semantic ID, i.e., a sequence of discrete tokens, and generates the next item through autoregressive decoding. While effective, existing autoregressive models face two intrinsic…

Information Retrieval · Computer Science 2025-11-12 Teng Shi , Chenglei Shen , Weijie Yu , Shen Nie , Chongxuan Li , Xiao Zhang , Ming He , Yan Han , Jun Xu