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Quantum heuristics have shown promise in solving various optimization problems, including lattice protein folding. Equally relevant is the inverse problem, protein design, where one seeks sequences that fold to a given target structure. The…

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

Fault-tolerant quantum computation with bosonic qubits often necessitates the use of noisy discrete-variable ancillae. In this work, we establish a comprehensive and practical fault-tolerance framework for such a hybrid system and…

Quantum Physics · Physics 2023-11-01 Qian Xu , Pei Zeng , Daohong Xu , Liang Jiang

Detection and segmentation of Brain tumor is very important because it provides anatomical information of normal and abnormal tissues which helps in treatment planning and patient follow-up. There are number of techniques for image…

Computer Vision and Pattern Recognition · Computer Science 2012-12-04 Minakshi Sharma

Deep neural networks (DNNs) have achieved remarkable success across diverse domains, but their performance can be severely degraded by noisy or corrupted training data. Conventional noise mitigation methods often rely on explicit…

Machine Learning · Computer Science 2025-06-16 Deliang Jin , Gang Chen , Shuo Feng , Yufeng Ling , Haoran Zhu

Quantum error mitigation, a data processing technique for recovering the statistics of target processes from their noisy version, is a crucial task for near-term quantum technologies. Most existing methods require prior knowledge of the…

Quantum Physics · Physics 2025-04-04 Manwen Liao , Yan Zhu , Giulio Chiribella , Yuxiang Yang

A new type of deterministic (non-probabilistic) computer logic system inspired by the stochasticity of brain signals is shown. The distinct values are represented by independent stochastic processes: independent voltage (or current) noises.…

General Physics · Physics 2010-04-05 Laszlo B. Kish

Variational quantum algorithms (VQAs) have shown strong evidences to gain provable computational advantages for diverse fields such as finance, machine learning, and chemistry. However, the heuristic ansatz exploited in modern VQAs is…

Variational quantum eigensolver (VQE), aiming at determining the ground state energy of a quantum system described by a Hamiltonian on noisy intermediate scale quantum (NISQ) devices, is among the most significant applications of…

Quantum Physics · Physics 2024-04-12 Ze-Tong Li , Fan-Xu Meng , Han Zeng , Zai-Chen Zhang , Xu-Tao Yu

Variational quantum machine learning algorithms have become the focus of recent research on how to utilize near-term quantum devices for machine learning tasks. They are considered suitable for this as the circuits that are run can be…

Quantum Physics · Physics 2022-12-20 Andrea Skolik , Stefano Mangini , Thomas Bäck , Chiara Macchiavello , Vedran Dunjko

We present a method to improve the convergence of variational algorithms based on hidden inverses to mitigate coherent errors. In the context of error mitigation, this means replacing the on hardware implementation of certain Hermitian…

Quantum Physics · Physics 2022-04-27 Vicente Leyton-Ortega , Swarnadeep Majumder , Raphael C. Pooser

Fidelity is one of the most valuable and commonly used metrics for assessing the performance of quantum circuits on error-prone quantum processors. Several approaches have been proposed to estimate circuit fidelity without executing it on…

Noise and errors are inevitable parts of any practical implementation of a quantum computer. As a result, large-scale quantum computation will require ways to detect and correct errors on quantum information. Here, we present such a quantum…

The role of inferencing with uncertainty is becoming more important in rule-based expert systems (ES), since knowledge given by a human expert is often uncertain or imprecise. We have succeeded in designing a VLSI chip which can perform an…

Artificial Intelligence · Computer Science 2013-04-12 Masaki Togai , Hiroyuki Watanabe

Quantum error correction assumes that all syndrome activations represent errors requiring correction. We present evidence from 756 QEC runs across three IBM Eagle r3 processors that this assumption is wrong. The hardware exhibits…

Quantum Physics · Physics 2026-04-15 Selina Stenberg

We present a quantum-native approach to quantum feature selection (QFS) based on analog quantum simulation with neutral atom arrays, adaptable to a variety of academic and industrial applications. In our method, feature relevance-measured…

Ever-increasing design complexity of System-on-Chips (SoCs) led to significant verification challenges. Unlike software, bugs in hardware design are vigorous and eternal i.e., once the hardware is fabricated, it cannot be repaired with any…

Hardware Architecture · Computer Science 2025-12-11 Deepak Narayan Gadde , Aman Kumar , Djones Lettnin , Sebastian Simon

While there has been a surge of recent interest in learning differential equation models from time series, methods in this area typically cannot cope with highly noisy data. We break this problem into two parts: (i) approximating the…

Machine Learning · Statistics 2020-12-08 Harish S. Bhat , Majerle Reeves , Ramin Raziperchikolaei

Quantum architecture search (QAS) has emerged to automate the design of high-performance quantum circuits under specific tasks and hardware constraints. We propose a noise-aware quantum architecture search (NA-QAS) framework based on…

Quantum Physics · Physics 2026-01-19 Chenlu Li , Hui Zeng , Dazhi Ding

We develop a hybrid framework for quantum parameter estimation in the presence of nuisance parameters. In this Bayes-point scheme, the parameters of interest are treated as fixed non-random parameters while nuisance parameters are…

Quantum Physics · Physics 2025-10-21 Jianchao Zhang , Jun Suzuki