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Cardiac magnetic resonance imaging (CMR) offers detailed evaluation of cardiac structure and function, but its limited accessibility restricts use to selected patient populations. In contrast, the electrocardiogram (ECG) is ubiquitous and…

The accurate interpretation of Electrocardiogram (ECG) signals is pivotal for diagnosing cardiovascular diseases. Integrating ECG signals with accompanying textual reports further holds immense potential to enhance clinical diagnostics by…

Machine Learning · Computer Science 2025-05-08 Hung Manh Pham , Aaqib Saeed , Dong Ma

Electrocardiogram (ECG) signals, profiling the electrical activities of the heart, are used for a plethora of diagnostic applications. However, ECG systems require multiple leads or channels of signals to capture the complete view of the…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Nabil Ibtehaz , Masood Mortazavi

An electrocardiogram (ECG) is a widely used, cost-effective tool for detecting electrical abnormalities in the heart. However, it cannot directly measure functional parameters, such as ventricular volumes and ejection fraction, which are…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Alexander Selivanov , Philip Müller , Özgün Turgut , Nil Stolt-Ansó , Daniel Rückert

Deep learning models have shown high accuracy in classifying electrocardiograms (ECGs), but their black box nature hinders clinical adoption due to a lack of trust and interpretability. To address this, we propose a novel three-stage…

Machine Learning · Computer Science 2025-12-09 Jose Geraldo Fernandes , Luiz Facury de Souza , Pedro Robles Dutenhefner , Gisele L. Pappa , Wagner Meira

The 12-lead electrocardiogram (ECG) is a quasi-periodic, multi-channel signal with diagnostic content spanning timescales from millisecond waveform morphology to multi-second rhythm dynamics. Existing ECG representation learning relies on…

Computational Engineering, Finance, and Science · Computer Science 2026-05-26 Lei Xu , Fahad Sohrab , Mehmet Yamac , Merja Heinaniemi , Moncef Gabbouj

Physiological signals such as electrocardiograms (ECG) and electroencephalograms (EEG) provide complementary insights into human health and cognition, yet multi-modal integration is challenging due to limited multi-modal labeled data, and…

Accurate interpretation of electrocardiogram (ECG) remains challenging due to the scarcity of labeled data and the high cost of expert annotation. Self-supervised learning (SSL) offers a promising solution by enabling models to learn…

Artificial Intelligence · Computer Science 2026-04-14 Zehao Qin , Xiaojian Lin , Ping Zhang , Hongliang Wu , Xinkang Wang , Guangling Liu , Bo Chen , Wenming Yang , Guijin Wang

Electrocardiogram (ECG) analysis is foundational for cardiovascular disease diagnosis, yet the performance of deep learning models is often constrained by limited access to annotated data. Self-supervised contrastive learning has emerged as…

Machine Learning · Computer Science 2025-08-22 Yi Yuan , Joseph Van Duyn , Runze Yan , Zhuoyi Huang , Sulaiman Vesal , Sergey Plis , Xiao Hu , Gloria Hyunjung Kwak , Ran Xiao , Alex Fedorov

Accurate segmentation of brain images typically requires the integration of complementary information from multiple image modalities. However, clinical data for all modalities may not be available for every patient, creating a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Haitao Li , Ziyu Li , Yiheng Mao , Zhengyao Ding , Zhengxing Huang

Recent advances in multimodal ECG representation learning center on aligning ECG signals with paired free-text reports. However, suboptimal alignment persists due to the complexity of medical language and the reliance on a full 12-lead…

Machine Learning · Computer Science 2025-02-26 Che Liu , Cheng Ouyang , Zhongwei Wan , Haozhe Wang , Wenjia Bai , Rossella Arcucci

Cardiovascular diseases (CVD) can be diagnosed using various diagnostic modalities. The electrocardiogram (ECG) is a cost-effective and widely available diagnostic aid that provides functional information of the heart. However, its ability…

Signal Processing · Electrical Eng. & Systems 2025-01-09 Özgün Turgut , Philip Müller , Paul Hager , Suprosanna Shit , Sophie Starck , Martin J. Menten , Eimo Martens , Daniel Rueckert

Electrocardiography (ECG) is a non-invasive tool for predicting cardiovascular diseases (CVDs). Current ECG-based diagnosis systems show promising performance owing to the rapid development of deep learning techniques. However, the label…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Rushuang Zhou , Lei Lu , Zijun Liu , Ting Xiang , Zhen Liang , David A. Clifton , Yining Dong , Yuan-Ting Zhang

Electronic health record (EHR) systems contain a wealth of multimodal clinical data including structured data like clinical codes and unstructured data such as clinical notes. However, many existing EHR-focused studies has traditionally…

Machine Learning · Statistics 2025-08-20 Tianxi Cai , Feiqing Huang , Ryumei Nakada , Linjun Zhang , Doudou Zhou

Modern diagnostic workflows are increasingly multimodal, integrating diverse data sources such as medical images, structured records, and physiological time series. Among these, electrocardiograms (ECGs) and chest X-rays (CXRs) are two of…

Machine Learning · Computer Science 2025-06-25 Vineet Punyamoorty , Aditya Malusare , Vaneet Aggarwal

Electrocardiogram (ECG) diagnosis remains challenging due to limited labeled data and the need to capture subtle yet clinically meaningful variations in rhythm and morphology. We present CREMA (Contrastive Regularized Masked Autoencoder), a…

Machine Learning · Computer Science 2025-08-22 Junho Song , Jong-Hwan Jang , DongGyun Hong , Joon-myoung Kwon , Yong-Yeon Jo

The utilization of deep learning on electrocardiogram (ECG) analysis has brought the advanced accuracy and efficiency of cardiac healthcare diagnostics. By leveraging the capabilities of deep learning in semantic understanding, especially…

Signal Processing · Electrical Eng. & Systems 2024-10-25 Han Yu , Peikun Guo , Akane Sano

Disentangled representation is a powerful technique to tackle domain shift problem in medical image analysis in unsupervised domain adaptation setting.However, previous methods only focus on exacting domain-invariant feature and ignore…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Shuai Wang , Rui Li

Learning representations of multimodal data that are both informative and robust to missing modalities at test time remains a challenging problem due to the inherent heterogeneity of data obtained from different channels. To address it, we…

Machine Learning · Computer Science 2022-11-21 Petra Poklukar , Miguel Vasco , Hang Yin , Francisco S. Melo , Ana Paiva , Danica Kragic

High-fidelity ECG interpretation is increasingly reliant on massive foundation models, yet their deployment in clinical edge-care remains hindered by extreme computational demands. While knowledge distillation (KD) is a promising solution,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Dang Hong Nguyen , Nhi Ngoc-Yen Nguyen , Huy-Hieu Pham
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