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Recent advances in DNA sequencing open prospects to make whole-genome analysis rapid and reliable, which is promising for various applications including personalized medicine. However, existing techniques for {\it de novo} genome assembly,…

Modern quantum annealers can find high-quality solutions to combinatorial optimisation objectives given as quadratic unconstrained binary optimisation (QUBO) problems. Unfortunately, obtaining suitable QUBO forms in computer vision remains…

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

Reference-guided DNA sequencing and alignment is an important process in computational molecular biology. The amount of DNA data grows very fast, and many new genomes are waiting to be sequenced while millions of private genomes need to be…

The de novo assembly of large, complex genomes is a significant challenge with currently available DNA sequencing technology. While many de novo assembly software packages are available, comparatively little attention has been paid to…

Genomics · Quantitative Biology 2013-07-31 Jared T. Simpson

Quantum Annealing (QA) and QAOA are promising quantum optimisation algorithms used for finding approximate solutions to combinatorial problems on near-term NISQ systems. Many NP-hard problems can be reformulated as Quadratic Unconstrained…

Quantum Physics · Physics 2025-10-06 Namasi G Sankar , Georgios Miliotis , Simon Caton

De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk

With the applications of quantum computing becoming more and more widespread, finding ways that allow end users without experience in the field to apply quantum computers to solve their individual problems is becoming a crucial task.…

Quantum Physics · Physics 2024-04-18 Damian Rovara , Nils Quetschlich , Robert Wille

The LogQ algorithm encodes Quadratic Unconstrained Binary Optimization (QUBO) problems, which are often encountered in the industry (portfolio optimization, fleet optimization, charging stations, etc.). It was developed within the framework…

Optimization and Control · Mathematics 2026-04-15 Jérémie Messud , Yagnik Chatterjee

Variational Quantum Algorithms (VQAs) are promising methods for solving combinatorial optimization problems on noisy intermediate-scale quantum (NISQ) devices. However, benchmarking VQAs is difficult due to their stochastic behavior and the…

Quantum Annealing (QA) can efficiently solve combinatorial optimization problems whose objective functions are represented by Quadratic Unconstrained Binary Optimization (QUBO) formulations. For broader applicability of QA, quadratization…

Quantum Physics · Physics 2025-07-29 Hyakka Nakada , Shu Tanaka

Decoding sparse quantum codes can be accomplished by syndrome-based decoding using a belief propagation (BP) algorithm.We significantly improve this decoding scheme by developing a new feedback adjustment strategy for the standard BP…

Quantum Physics · Physics 2013-09-25 Yun-Jiang Wang , Barry C. Sanders , Bao-Ming Bai , Xin-Mei Wang

We present a number of quantum computing patterns that build on top of fundamental algorithms, that can be applied to solving concrete, NP-hard problems. In particular, we introduce the concept of a quantum dictionary as a summation of…

We consider the task of deterministically entangling two remote qubits using joint measurement and feedback, but no directly entangling Hamiltonian. In order to formulate the most effective experimentally feasible protocol, we introduce the…

Quantum Physics · Physics 2015-12-16 Leigh Martin , Felix Motzoi , Hanhan Li , Mohan Sarovar , Birgitta Whaley

Variational quantum algorithms (VQAs) are leading strategies to reach practical utilities of near-term quantum devices. However, the no-cloning theorem in quantum mechanics precludes standard backpropagation, leading to prohibitive quantum…

Quantum Physics · Physics 2025-09-26 Yiming Huang , Yajie Hao , Jing Zhou , Xiao Yuan , Xiaoting Wang , Yuxuan Du

We propose a quantum-assisted reconstruction framework for high-resolution tomographic imaging that significantly reduces both qubit requirements and radiation exposure. Conventional quantum reconstruction methods require solving QUBO…

Quantum Physics · Physics 2025-04-30 Hyunju Lee , Kyungtaek Jun

In this paper, we develop a way to encode several NP-Complete problems in Abstract Argumentation to Quadratic Unconstrained Binary Optimization (QUBO) problems. In this form, a solution for a QUBO problem involves minimizing a quadratic…

Quantum Physics · Physics 2024-09-10 Marco Baioletti , Francesco Santini

Optimizing routing in Wireless Sensor Networks (WSNs) is pivotal for minimizing energy consumption and extending network lifetime. This paper introduces a resourceefficient compilation method for distributed quantum circuits tailored to…

Quantum Physics · Physics 2025-01-20 Kuan-Cheng Chen , Felix Burt , Shang Yu , Chen-Yu Liu , Min-Hsiu Hsieh , Kin K. Leung

Generative Adversarial Networks (GANs) represent an attractive and novel approach to generate realistic data, such as genes, proteins, or drugs, in synthetic biology. Here, we apply GANs to generate synthetic DNA sequences encoding for…

Genomics · Quantitative Biology 2018-04-06 Anvita Gupta , James Zou

We employ a machine learning-enabled approach to quantum state engineering based on evolutionary algorithms. In particular, we focus on superconducting platforms and consider a network of qubits -- encoded in the states of artificial atoms…

Quantum Physics · Physics 2023-01-26 Jonathon Brown , Mauro Paternostro , Alessandro Ferraro