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Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently, Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Hao Li , Ying Chen , Yifei Chen , Wenxian Yang , Bowen Ding , Yuchen Han , Liansheng Wang , Rongshan Yu

Few-shot learning presents a critical solution for cancer diagnosis in computational pathology (CPath), addressing fundamental limitations in data availability, particularly the scarcity of expert annotations and patient privacy…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Zhengrui Guo , Conghao Xiong , Jiabo Ma , Qichen Sun , Lishuang Feng , Jinzhuo Wang , Hao Chen

Recent advances in histopathology vision-language foundation models (VLFMs) have shown promise in addressing data scarcity for whole slide image (WSI) classification via zero-shot adaptation. However, these methods remain outperformed by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Tianqi Xiang , Yi Li , Qixiang Zhang , Xiaomeng Li

Existing text-to-image diffusion models have demonstrated remarkable capabilities in generating high-quality images guided by textual prompts. However, achieving multi-subject compositional synthesis with precise spatial control remains a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Fei Peng , Junqiang Wu , Yan Li , Tingting Gao , Di Zhang , Huiyuan Fu

Few-shot segmentation (FSS) aims to segment novel classes under the guidance of limited support samples by a meta-learning paradigm. Existing methods mainly mine references from support images as meta guidance. However, due to intra-class…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Jin Wang , Bingfeng Zhang , Jian Pang , Mengyu Liu , Honglong Chen , Weifeng Liu

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Accurate biomedical image classification under low-resource conditions remains challenging due to limited annotations, subtle inter-class visual differences, and complex disease semantics. While vision--language models offer a promising…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xiaoliu Luo , Minxue Xiao , Ting Xie , Mengzhu Wang , Huiqing Qi , Joey Tianyi Zhou , Taiping Zhang , Xu Wang

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Few-shot learning aims to identify novel categories from only a handful of labeled samples, where prototypes estimated from scarce data are often biased and generalize poorly. Semantic-based methods alleviate this by introducing coarse…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jiaying Wu , Can Gao , Jinglu Hu , Hui Li , Xiaofeng Cao , Jingcai Guo

Despite significant progress in Unified Multimodal Retrieval (UMR) powered by Large Multimodal Models (LMMs), existing embedding methods primarily focus on sample-level objectives via contrastive learning while overlooking the crucial…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Guosheng Zhang , Linkai Liu , Keyao Wang , Haixiao Yue , Zhiwen Tan , Xiao Tan

Vision-language supervision has made remarkable strides in learning visual representations from textual guidance. In digital pathology, vision-language models (VLM), pre-trained on curated datasets of histological image-captions, have been…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Foundation Vision-Language Models (VLMs) like CLIP exhibit strong generalization capabilities due to large-scale pretraining on diverse image-text pairs. However, their performance often degrades when applied to target datasets with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Debarshi Brahma , Soma Biswas

Few-shot learning (FSL) aims to recognize new concepts using a limited number of visual samples. Existing approaches attempt to incorporate semantic information into the limited visual data for category understanding. However, these methods…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Mushui Liu , Fangtai Wu , Bozheng Li , Ziqian Lu , Yunlong Yu , Xi Li

We introduce MUSE-VL, a Unified Vision-Language Model through Semantic discrete Encoding for multimodal understanding and generation. Recently, the research community has begun exploring unified models for visual generation and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Rongchang Xie , Chen Du , Ping Song , Chang Liu

Multi-modal learning adeptly integrates visual and textual data, but its application to histopathology image and text analysis remains challenging, particularly with large, high-resolution images like gigapixel Whole Slide Images (WSIs).…

Computer Vision and Pattern Recognition · Computer Science 2024-05-29 Quan Liu , Ruining Deng , Can Cui , Tianyuan Yao , Vishwesh Nath , Yucheng Tang , Yuankai Huo

Vision-language models (VLMs) have recently been integrated into multiple instance learning (MIL) frameworks to address the challenge of few-shot, weakly supervised classification of whole slide images (WSIs). A key trend involves…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Bryan Wong , Jong Woo Kim , Huazhu Fu , Mun Yong Yi

The application of visual instruction tuning and other post-training techniques has significantly enhanced the capabilities of Large Language Models (LLMs) in visual understanding, enriching Vision-Language Models (VLMs) with more…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Mingjie Xu , Andrew Estornell , Hongzheng Yang , Yuzhi Zhao , Zhaowei Zhu , Qi Xuan , Jiaheng Wei
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