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Self-driving laboratories have begun to replace human experimenters in performing single experimental skills or predetermined experimental protocols. However, as the pace of idea iteration in scientific research has been intensified by…

Artificial Intelligence · Computer Science 2025-04-08 Yu-Zhe Shi , Mingchen Liu , Fanxu Meng , Qiao Xu , Zhangqian Bi , Kun He , Lecheng Ruan , Qining Wang

The control of complex laboratory instrumentation often requires significant programming expertise, creating a barrier for researchers lacking computational skills. This work explores the potential of large language models (LLMs), such as…

Artificial Intelligence · Computer Science 2026-04-07 Yong Xie , Kexin He , Andres Castellanos-Gomez

The prevailing paradigm in AI for physical systems (scaling general-purpose foundation models toward universal multimodal reasoning) confronts a fundamental barrier at the control interface. Recent benchmarks show that even frontier…

Artificial Intelligence · Computer Science 2026-05-21 Yoon Pyo Lee , Samrendra Roy , Jay Yoo , Kazuma Kobayashi , Sajedul Talukder , Seid Koric , Souvik Chakraborty , Syed Bahauddin Alam

Large Language Models (LLMs) have shown remarkable success in supporting a wide range of knowledge-intensive tasks. In specialized domains, there is growing interest in leveraging LLMs to assist subject matter experts with domain-specific…

Computation and Language · Computer Science 2025-12-01 Aman Kumar , Ekant Muljibhai Amin , Xian Yeow Lee , Lasitha Vidyaratne , Ahmed K. Farahat , Dipanjan D. Ghosh , Yuta Koreeda , Chetan Gupta

We present an advanced scanning probe microscopy system enhanced with artificial intelligence (AI-SPM) designed for self-driving atomic-scale measurements. This system expertly identifies and manipulates atomic positions with high…

Computational Physics · Physics 2024-04-18 Zhuo Diao , Keiichi Ueda , Linfeng Hou , Fengxuan Li , Hayato Yamashita , Masayuki Abe

Statistical model discovery is a challenging search over a vast space of models subject to domain-specific constraints. Efficiently searching over this space requires expertise in modeling and the problem domain. Motivated by the domain…

Machine Learning · Computer Science 2024-06-25 Michael Y. Li , Emily B. Fox , Noah D. Goodman

Model-driven software development is a promising way to cope with the complexity of system integration in advanced robotics, as it already demonstrated its benefits in domains with comparably challenging system integration requirements.…

Robotics · Computer Science 2013-02-27 Arne Nordmann , Sebastian Wrede

Autonomous scientific research, capable of independently conducting complex experiments and serving non-specialists, represents a long-held aspiration. Achieving it requires a fundamental paradigm shift driven by artificial intelligence…

Artificial Intelligence · Computer Science 2025-07-04 Mingyu Wu , Zhaoguo Wang , Jiabin Wang , Zhiyuan Dong , Jingkai Yang , Qingting Li , Tianyu Huang , Lei Zhao , Mingqiang Li , Fei Wang , Chunhai Fan , Haibo Chen

With the advent of large language models (LLMs), in both the open source and proprietary domains, attention is turning to how to exploit such artificial intelligence (AI) systems in assisting complex scientific tasks, such as material…

Human-Computer Interaction · Computer Science 2024-01-26 Yongtao Liu , Marti Checa , Rama K. Vasudevan

Artificial intelligence (AI) methods have become critical in scientific applications to help accelerate scientific discovery. Large language models (LLMs) are being considered as a promising approach to address some of the challenging…

Self-driving laboratories (SDLs) close the loop between experiment design, automated execution, and data-driven decision making, and they provide a demanding testbed for agentic AI under expensive actions, noisy and delayed feedback, strict…

Artificial Intelligence · Computer Science 2026-01-27 Xuanzhou Chen , Audrey Wang , Stanley Yin , Hanyang Jiang , Dong Zhang

Autonomous tuning of particle accelerators is an active and challenging field of research with the goal of enabling novel accelerator technologies cutting-edge high-impact applications, such as physics discovery, cancer research and…

Computation and Language · Computer Science 2024-05-16 Jan Kaiser , Annika Eichler , Anne Lauscher

Materials with bespoke properties have long been identified by computational searches, and their experimental realisation is now coming within reach through autonomous laboratories. Scattering experiments are central to verifying the atomic…

Large Language Models (LLMs) have significant impact on the healthcare scenarios but remain prohibitively large for deployment in real-time, resource-constrained environments such as edge devices. In this work, we introduce a novel medical…

Computation and Language · Computer Science 2025-08-08 Uttej Kallakurik , Edward Humes , Rithvik Jonna , Xiaomin Lin , Tinoosh Mohsenin

With advances in large language models (LLMs), researchers are creating new systems that can perform AI-driven analytics over large unstructured datasets. Recent work has explored executing such analytics queries using semantic operators --…

Artificial Intelligence · Computer Science 2025-09-04 Matthew Russo , Tim Kraska

Background:Technical systems are growing in complexity with more components and functions across various disciplines. Model-Driven Engineering (MDE) helps manage this complexity by using models as key artifacts. Domain-Specific Languages…

Software Engineering · Computer Science 2025-01-13 Simon Raedler , Luca Berardinelli , Karolin Winter , Abbas Rahimi , Stefanie Rinderle-Ma

Scientific discovery increasingly depends on efficient experimental optimization to navigate vast design spaces under time and resource constraints. Traditional approaches often require extensive domain expertise and feature engineering.…

Machine Learning · Computer Science 2025-11-10 Bojana Ranković , Ryan-Rhys Griffiths , Philippe Schwaller

Accurate representation of procedures in restricted scenarios, such as non-standardized scientific experiments, requires precise depiction of constraints. Unfortunately, Domain-specific Language (DSL), as an effective tool to express…

Robotics · Computer Science 2024-10-31 Yu-Zhe Shi , Haofei Hou , Zhangqian Bi , Fanxu Meng , Xiang Wei , Lecheng Ruan , Qining Wang

Artificial intelligence (AI) is widely deployed to solve problems related to marketing attribution and budget optimization. However, AI models can be quite complex, and it can be difficult to understand model workings and insights without…

Computation and Language · Computer Science 2024-04-23 Yilin Gao , Sai Kumar Arava , Yancheng Li , James W. Snyder

Large Language Models (LLMs) have emerged as powerful tools for accelerating scientific discovery, yet their static knowledge and hallucination issues hinder autonomous research applications. Recent advances integrate LLMs into agentic…

Artificial Intelligence · Computer Science 2025-12-23 Zeyu Xia , Jinzhe Ma , Congjie Zheng , Shufei Zhang , Yuqiang Li , Hang Su , P. Hu , Changshui Zhang , Xingao Gong , Wanli Ouyang , Lei Bai , Dongzhan Zhou , Mao Su
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