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The evolution of ransomware requires the development of more sophisticated detection methodologies capable of identifying malicious behaviors beyond traditional signature-based and heuristic techniques. The proposed Hierarchical…
A model's ability to express its own predictive uncertainty is an essential attribute for maintaining clinical user confidence as computational biomarkers are deployed into real-world medical settings. In the domain of cancer digital…
Healthcare foundation models have largely followed paradigms from natural language processing and computer vision, emphasizing large scale pretraining and deterministic representations over heterogeneous clinical data. However, clinical…
Decision tree ensembles are widely used in critical domains, making robustness and sensitivity analysis essential to their trustworthiness. We study the feature sensitivity problem, which asks whether an ensemble is sensitive to a specified…
In science, we are interested not only in forecasting but also in understanding how predictions are made, specifically what the interpretable underlying model looks like. Data-driven machine learning technology can significantly streamline…
This paper establishes the privacy-preserving Cram\'er-Rao (CR) lower bound theory, characterizing the fundamental limit of identification accuracy under privacy constraint. An identifiability criterion under privacy constraint is derived…
Hierarchical Latent Attribute Models (HLAMs) are a family of discrete latent variable models that are attracting increasing attention in educational, psychological, and behavioral sciences. The key ingredients of an HLAM include a binary…
Parameter inference is a fundamental problem in data-driven modeling. Given observed data that is believed to be a realization of some parameterized model, the aim is to find parameter values that are able to explain the observed data. In…
Sequential Monte Carlo (SMC) algorithms represent a suite of robust computational methodologies utilized for state estimation and parameter inference within dynamical systems, particularly in real-time or online environments where data…
The interactions between parameters, model structure, and outputs can determine what inferences, predictions, and control strategies are possible for a given system. Parameter space reduction and parameter estimation---and, more generally,…
To address the challenge of limited experimental materials data, extensive physical property databases are being developed based on high-throughput computational experiments, such as molecular dynamics simulations. Previous studies have…
We introduce a novel Bayesian hybrid matrix factorisation model (HMF) for data integration, based on combining multiple matrix factorisation methods, that can be used for in- and out-of-matrix prediction of missing values. The model is very…
Motivated by statistical inference problems in high-dimensional time series data analysis, we first derive non-asymptotic error bounds for Gaussian approximations of sums of high-dimensional dependent random vectors on hyper-rectangles,…
The physics of a closed quantum mechanical system is governed by its Hamiltonian. However, in most practical situations, this Hamiltonian is not precisely known, and ultimately all there is are data obtained from measurements on the system.…
Assured AI in unrestricted settings is a critical problem. Our framework addresses AI assurance challenges lying at the intersection of domain adaptation, fairness, and counterfactuals analysis, operating via the discovery and intervention…
This paper presents a machine learning framework for Bayesian systems identification from noisy, sparse and irregular observations of nonlinear dynamical systems. The proposed method takes advantage of recent developments in differentiable…
Missing data is a ubiquitous challenge in data analysis, often leading to biased and inaccurate results. Traditional imputation methods usually assume that the missingness mechanism is missing-at-random (MAR), where the missingness is…
We introduce two practical properties of hierarchical clustering methods for (possibly asymmetric) network data: excisiveness and linear scale preservation. The latter enforces imperviousness to change in units of measure whereas the former…
Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…
Deep learning and data-driven approaches have shown great potential in scientific domains. The promise of data-driven techniques relies on the availability of a large volume of high-quality training datasets. Due to the high cost of…