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Over the past decade, AI research has focused heavily on building ever-larger deep learning models. This approach has simultaneously unlocked incredible achievements in science and technology, and hindered AI from overcoming long-standing…

Computers and Society · Computer Science 2024-04-12 Bernard J. Koch , David Peterson

Leveraging Multi-modal Large Language Models (MLLMs) to accelerate frontier scientific research is promising, yet how to rigorously evaluate such systems remains unclear. Existing benchmarks mainly focus on single-document understanding,…

Artificial Intelligence · Computer Science 2026-04-14 Lei Xiong , Huaying Yuan , Zheng Liu , Zhao Cao , Zhicheng Dou

As AI promises to accelerate scientific discovery, it remains unclear whether fully AI-driven research is possible and whether it can adhere to key scientific values, such as transparency, traceability and verifiability. Mimicking human…

Other Quantitative Biology · Quantitative Biology 2024-04-30 Tal Ifargan , Lukas Hafner , Maor Kern , Ori Alcalay , Roy Kishony

Since language models (LMs) now outperform average humans on many challenging tasks, it has become increasingly difficult to develop challenging, high-quality, and realistic evaluations. We address this issue by examining LMs' capabilities…

The rapid growth of academic literature makes the manual creation of scientific surveys increasingly infeasible. While large language models show promise for automating this process, progress in this area is hindered by the absence of…

Computation and Language · Computer Science 2026-05-05 Weihang Su , Anzhe Xie , Qingyao Ai , Jianming Long , Xuanyi Chen , Jiaxin Mao , Ziyi Ye , Yiqun Liu

High-quality scientific review and perspective papers require substantial time and effort, limiting researchers' ability to synthesize emerging knowledge. While Large Language Models (LLMs) leverage AI Scientists for scientific workflows,…

Artificial Intelligence · Computer Science 2026-03-03 Sasi Kiran Gaddipati , Farhana Keya , Gollam Rabby , Sören Auer

The prevailing model for disseminating scientific knowledge relies on individual publications dispersed across numerous journals and archives. This legacy system is ill suited to the recent exponential proliferation of publications,…

Scientific research communities are embracing AI-based solutions to target tractable scientific tasks and improve research workflows. However, the development and evaluation of such solutions are scattered across multiple disciplines. We…

Artificial Intelligence · Computer Science 2022-06-14 Yatao Li , Jianfeng Zhan

The realization of autonomous scientific experimentation is currently limited by LLMs' struggle to grasp the strict procedural logic and accuracy required by biological protocols. To address this fundamental challenge, we present…

Computation and Language · Computer Science 2026-01-22 Yuyang Liu , Liuzhenghao Lv , Xiancheng Zhang , Jingya Wang Li Yuan , Yonghong Tian

The volume of scientific submissions continues to climb, outpacing the capacity of qualified human referees and stretching editorial timelines. At the same time, modern large language models (LLMs) offer impressive capabilities in…

Artificial Intelligence · Computer Science 2026-04-28 Jialiang Wang , Yuchen Liu , Hang Xu , Kaichun Hu , Shimin Di , Wangze Ni , Linan Yue , Min-Ling Zhang , Kui Ren , Lei Chen

The paradigm of agentic science requires AI systems to conduct robust reasoning and engage in long-horizon, autonomous exploration. However, current scientific benchmarks remain confined to domain knowledge comprehension and complex…

There is growing interest in hypothesis generation with large language models (LLMs). However, fundamental questions remain: what makes a good hypothesis, and how can we systematically evaluate methods for hypothesis generation? To address…

Artificial Intelligence · Computer Science 2026-02-12 Haokun Liu , Sicong Huang , Jingyu Hu , Yangqiaoyu Zhou , Chenhao Tan

Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene…

The development of LLM agents has led to a growing body of work on knowledge-work AI, including coding, research, and healthcare. However, current knowledge-work evaluation and benchmark design still largely follow the logic of traditional…

Artificial Intelligence · Computer Science 2026-05-25 Yining Hua , Hongbin Na , Cyrus Ayubcha , Levi Lian

The integration of Agentic AI into scientific discovery marks a new frontier in research automation. These AI systems, capable of reasoning, planning, and autonomous decision-making, are transforming how scientists perform literature…

Computation and Language · Computer Science 2025-03-13 Mourad Gridach , Jay Nanavati , Khaldoun Zine El Abidine , Lenon Mendes , Christina Mack

With recent Nobel Prizes recognising AI contributions to science, Large Language Models (LLMs) are transforming scientific research by enhancing productivity and reshaping the scientific method. LLMs are now involved in experimental design,…

Artificial intelligence (AI) - and specifically machine learning (ML) - applications for climate prediction across timescales are proliferating quickly. The emergence of these methods prompts a revisit to the impact of data preprocessing, a…

As the mathematical capabilities of large language models (LLMs) improve, it becomes increasingly important to evaluate their performance on research-level tasks at the frontier of mathematical knowledge. However, existing benchmarks are…