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Protein Language Models (PLMs) such as ESM2 have been shown to be capable of zero-shot prediction of critical scalar properties of proteins (fitness). In this work, we show that injecting a dropout layer at inference time between a PLM's…

Machine Learning · Computer Science 2025-06-19 Aditya Ravuri , Neil D. Lawrence

Large language models (LLMs) are remarkably efficient across a wide range of natural language processing tasks and well beyond them. However, a comprehensive theoretical analysis of the LLMs' generalization capabilities remains elusive. In…

Large Language Models (LLMs) stand at the forefront of a number of Natural Language Processing (NLP) tasks. Despite the widespread adoption of LLMs in NLP, much of their potential in broader fields remains largely unexplored, and…

Machine Learning · Computer Science 2024-03-11 Zhiqiang Zhong , Kuangyu Zhou , Davide Mottin

Designing proteins with desired functions or properties represents a core goal in synthetic biology and drug discovery. Recent advances in protein language models (PLMs) have enabled the generation of highly designable protein sequences,…

Machine Learning · Computer Science 2026-05-12 Yulin Zhang , He Cao , Zihao Jiang , Chenyi Zi , Zhipeng Zhou , Zijing Liu , Yu Li , Jia Li , Ziqi Gao

Protein engineering is an emerging field in biotechnology that has the potential to revolutionize various areas, such as antibody design, drug discovery, food security, ecology, and more. However, the mutational space involved is too vast…

Biomolecules · Quantitative Biology 2023-07-28 Yuchi Qiu , Guo-Wei Wei

In this article, we explore the shallow heuristics used by transformer-based pre-trained language models (PLMs) that are fine-tuned for natural language inference (NLI). To do so, we construct or own dataset based on syllogistic, and we…

Computation and Language · Computer Science 2022-01-20 Reto Gubelmann , Siegfried Handschuh

Fine-tuning and inference with large Language Models (LM) are generally known to be expensive. Parameter-efficient fine-tuning over pretrained LMs reduces training memory by updating a small number of LM parameters but does not improve…

Computation and Language · Computer Science 2024-06-05 Bowen Zhao , Hannaneh Hajishirzi , Qingqing Cao

Large language models (LLMs) demonstrate strong performance as text embedding models when finetuned with supervised contrastive training. However, their large size balloons inference time and memory requirements. In this paper, we show that…

Computation and Language · Computer Science 2024-10-21 Thennal D K , Tim Fischer , Chris Biemann

Particularly in low-data regimes, an outstanding challenge in machine learning is developing principled techniques for augmenting our models with suitable priors. This is to encourage them to learn in ways that are compatible with our…

Machine Learning · Computer Science 2022-10-25 Kristy Choi , Chris Cundy , Sanjari Srivastava , Stefano Ermon

Multilingual pre-trained language models (PLMs) have demonstrated impressive performance on several downstream tasks for both high-resourced and low-resourced languages. However, there is still a large performance drop for languages unseen…

Computation and Language · Computer Science 2022-10-19 Jesujoba O. Alabi , David Ifeoluwa Adelani , Marius Mosbach , Dietrich Klakow

The advent of Large Language Models (LLMs) has raised concerns about their enormous carbon footprint, starting with energy-intensive training and continuing through repeated inference. This study investigates the potential of using…

Computation and Language · Computer Science 2026-01-15 Anandita Garg , Uma Gaba , Deepan Muthirayan , Anish Roy Chowdhury

Adapter-based tuning has recently arisen as an alternative to fine-tuning. It works by adding light-weight adapter modules to a pretrained language model (PrLM) and only updating the parameters of adapter modules when learning on a…

Computation and Language · Computer Science 2021-06-08 Ruidan He , Linlin Liu , Hai Ye , Qingyu Tan , Bosheng Ding , Liying Cheng , Jia-Wei Low , Lidong Bing , Luo Si

Log analysis represents a critical sub-domain within AI applications that facilitates automatic approaches to fault and error management of large-scaled software systems, saving labors of traditional manual methods. While existing solutions…

Computation and Language · Computer Science 2025-08-27 Yuhe Ji , Yilun Liu , Feiyu Yao , Minggui He , Shimin Tao , Xiaofeng Zhao , Su Chang , Xinhua Yang , Weibin Meng , Yuming Xie , Boxing Chen , Shenglin Zhang , Yongqian Sun

The fields of generative AI and transfer learning have experienced remarkable advancements in recent years especially in the domain of Natural Language Processing (NLP). Transformers have been at the heart of these advancements where the…

Computation and Language · Computer Science 2024-02-28 Majd Saleh , Stéphane Paquelet

Large Language Models (LLMs) have shown remarkable performance in various natural language processing tasks but face challenges in mathematical reasoning, where complex problem-solving requires both linguistic understanding and mathematical…

Computation and Language · Computer Science 2025-03-20 Shuguang Chen , Guang Lin

Large language models (LLMs) are increasingly used to support the analysis of complex financial disclosures, yet their reliability, behavioral consistency, and transparency remain insufficiently understood in high-stakes settings. This…

Computation and Language · Computer Science 2026-01-21 Md Talha Mohsin

A recent study (Kuribayashi et al., 2025) has shown that human sentence processing behavior, typically measured on syntactically unchallenging constructions, can be effectively modeled using surprisal from early layers of large language…

Computation and Language · Computer Science 2026-04-21 Tatsuki Kuribayashi , Alex Warstadt , Yohei Oseki , Ethan Gotlieb Wilcox

Phase transitions have been proposed as the origin of emergent abilities in large language models (LLMs), where new capabilities appear abruptly once models surpass critical thresholds of scale. Prior work, such as that of Wei et al.,…

Computation and Language · Computer Science 2025-11-18 Noah Hong , Tao Hong

Large language models(LLMs) containing tens of billions of parameters (or even more) have demonstrated impressive capabilities in various NLP tasks. However, substantial model size poses challenges to training, inference, and deployment so…

Artificial Intelligence · Computer Science 2023-10-11 Yupeng Ji , Yibo Cao , Jiucai Liu

Proteins, as essential biomolecules, play a central role in biological processes, including metabolic reactions and DNA replication. Accurate prediction of their properties and functions is crucial in biological applications. Recent…

Computation and Language · Computer Science 2025-05-30 Wei Wu , Chao Wang , Liyi Chen , Mingze Yin , Yiheng Zhu , Kun Fu , Jieping Ye , Hui Xiong , Zheng Wang
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