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The rapid adoption of synthetic data for training Large Language Models (LLMs) has introduced the technical challenge of "model collapse"-a degenerative process where recursive training on model-generated content leads to a contraction of…

Machine Learning · Computer Science 2026-03-24 Yi Gu , Lingyou Pang , Xiangkun Ye , Tianyu Wang , Jianyu Lin , Carey E. Priebe , Alexander Aue

Recently, the state space model (SSM) represented by Mamba has shown remarkable performance in long-term sequence modeling tasks, including speech enhancement. However, due to substantial differences in sub-band features, applying the same…

Sound · Computer Science 2025-02-25 Jizhen Li , Weiping Tu , Yuhong Yang , Xinmeng Xu , Yiqun Zhang , Yanzhen Ren

Chemical Exchange Saturation Transfer (CEST) Magnetic Resonance Imaging (MRI) is a molecular imaging methodology capable of mapping brain metabolites with relatively high spatial resolution. Specificity is the main goal of such experiments;…

Medical Physics · Physics 2020-01-24 Frederico Severo , Noam Shemesh

Renormalization group (RG) methods, which model the way in which the effective behavior of a system depends on the scale at which it is observed, are key to modern condensed-matter theory and particle physics. We compare the ideas behind…

Quantum Physics · Physics 2013-03-14 Cédric Bény

The application of Deep Learning (DL) for medical diagnosis is often hampered by two problems. First, the amount of training data may be scarce, as it is limited by the number of patients who have acquired the condition to be diagnosed.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Diyuan Lu , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

This paper investigates methods for improving generative data augmentation for deep learning. Generative data augmentation leverages the synthetic samples produced by generative models as an additional dataset for classification with small…

Machine Learning · Computer Science 2023-10-24 Shin'ya Yamaguchi , Daiki Chijiwa , Sekitoshi Kanai , Atsutoshi Kumagai , Hisashi Kashima

Synthetic data augmentation helps language models learn new knowledge in data-constrained domains. However, naively scaling existing synthetic data methods by training on more synthetic tokens or using stronger generators yields diminishing…

Machine Learning · Computer Science 2026-03-31 Seungju Han , Konwoo Kim , Chanwoo Park , Benjamin Newman , Suhas Kotha , Jaehun Jung , James Zou , Yejin Choi

One of the great challenges in biology is to observe, at sufficient detail, the real-time workings of the cell. Many methods exist to do cell measurements invasively. For example, mass spectrometry has tremendous mass sensitivity but…

Quantitative Methods · Quantitative Biology 2017-10-23 Jan G. Korvink , Neil MacKinnon

Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Nanna E. Wielenberg , Ilinca Popp , Oliver Blanck , Lucas Zander , Jan C. Peeken , Stephanie E. Combs , Anca-Ligia Grosu , Dimos Baltas , Tobias Fechter

During the last decade, a large number of different numerical methods have been proposed to tackle the automatic identification and quantification in {\gamma}-ray spectrometry. However, the lack of common benchmarks, including datasets,…

Machine Learning · Computer Science 2025-08-13 Dinh Triem Phan , Jérôme Bobin , Cheick Thiam , Christophe Bobin

Representational Similarity Analysis (RSA) is a popular method for analyzing neuroimaging and behavioral data. Here we evaluate the accuracy and reliability of RSA in the context of model selection, and compare it to that of regression.…

Methodology · Statistics 2025-11-18 Chuanji Gao , Gang Chen , Svetlana V. Shinkareva , Rutvik H. Desai

A deep neural network (NN) is used to simultaneously detect laser beams in images and measure their center coordinates, radii and angular orientations. A dataset of images containing simulated laser beams and a dataset of images with…

Optics · Physics 2022-02-17 Lucas R. Hofer , Milan Krstajić , Robert P. Smith

We derive a new margin-based regularization formulation, termed multi-margin regularization (MMR), for deep neural networks (DNNs). The MMR is inspired by principles that were applied in margin analysis of shallow linear classifiers, e.g.,…

Machine Learning · Computer Science 2020-09-15 Berry Weinstein , Shai Fine , Yacov Hel-Or

Incomplete knowledge of metabolic processes hinders the accuracy of GEnome-scale Metabolic models (GEMs), which in turn impedes advancements in systems biology and metabolic engineering. Existing gap-filling methods typically rely on…

Molecular Networks · Quantitative Biology 2024-09-23 Xiaoyi Liu , Hongpeng Yang , Chengwei Ai , Ruihan Dong , Yijie Ding , Qianqian Yuan , Jijun Tang , Fei Guo

Glioblastoma, a highly aggressive brain tumor with diverse molecular and pathological features, poses a diagnostic challenge due to its heterogeneity. Accurate diagnosis and assessment of this heterogeneity are essential for choosing the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Juexin Zhang , Ying Weng , Ke Chen

Although deep learning models for abnormality classification can perform well in screening mammography, the demographic, imaging, and clinical characteristics associated with increased risk of model failure remain unclear. This…

Raman spectroscopy, a photonic modality based on the inelastic backscattering of coherent light, is a valuable asset to the intraoperative sensing space, offering non-ionizing potential and highly-specific molecular fingerprint-like…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Ashutosh Raman , Ren A. Odion , Kent K. Yamamoto , Weston Ross , Tuan Vo-Dinh , Patrick J. Codd

Medical image segmentation plays an important role in various clinical applications; however, existing deep learning models face trade-offs between efficiency and accuracy. Convolutional Neural Networks (CNNs) capture local details well but…

Image and Video Processing · Electrical Eng. & Systems 2025-10-20 Saqib Qamar , Mohd Fazil , Parvez Ahmad , Shakir Khan , Abu Taha Zamani

The generalization performance of deep learning models for medical image analysis often decreases on images collected with different devices for data acquisition, device settings, or patient population. A better understanding of the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Aleksandar Vakanski , Min Xian

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang
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