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Purpose: Magnetic Resonance Imaging (MRI) enables non-invasive assessment of brain abnormalities during early life development. Permanent magnet scanners operating in the neonatal intensive care unit (NICU) facilitate MRI of sick infants,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-23 Yamin Arefeen , Brett Levac , Bhairav Patel , Chang Ho , Jonathan I. Tamir

We propose a Bayesian framework for fine-tuning large diffusion models with a novel network structure called Bayesian Power Steering (BPS). We clarify the meaning behind adaptation from a \textit{large probability space} to a \textit{small…

Machine Learning · Computer Science 2024-06-07 Ding Huang , Ting Li , Jian Huang

Denoising Diffusion Probabilistic Models (DDPMs) have garnered popularity for data generation across various domains. However, a significant bottleneck is the necessity for whole-network computation during every step of the generative…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Shuai Yang , Yukang Chen , Luozhou Wang , Shu Liu , Yingcong Chen

Discrete diffusion models generate sequences by iteratively denoising samples corrupted by categorical noise, offering an appealing alternative to autoregressive decoding for structured and symbolic generation. However, standard training…

Machine Learning · Computer Science 2026-02-04 Huu Binh Ta , Michael Cardei , Alvaro Velasquez , Ferdinando Fioretto

This work proposes a novel channel estimator based on diffusion models (DMs), one of the currently top-rated generative models. Contrary to related works utilizing generative priors, a lightweight convolutional neural network (CNN) with…

Signal Processing · Electrical Eng. & Systems 2024-03-07 Benedikt Fesl , Michael Baur , Florian Strasser , Michael Joham , Wolfgang Utschick

Proteins are fundamental to biology, executing diverse functions through complex physicochemical interactions, and they hold transformative potential across medicine, materials science, and environmental applications. Protein Language…

Biomolecules · Quantitative Biology 2025-06-11 Logan Hallee , Nikolaos Rafailidis , David B. Bichara , Jason P. Gleghorn

In an inverse problem, the goal is to recover an unknown parameter (e.g., an image) that has typically undergone some lossy or noisy transformation during measurement. Recently, deep generative models, particularly diffusion models, have…

Machine Learning · Computer Science 2025-07-30 Amartya Banerjee , Xingyu Xu , Caroline Moosmüller , Harlin Lee

Generative modeling has recently undergone remarkable advancements, primarily propelled by the transformative implications of Diffusion Probabilistic Models (DPMs). The impressive capability of these models, however, often entails…

Machine Learning · Computer Science 2023-10-03 Gongfan Fang , Xinyin Ma , Xinchao Wang

Accurate prediction of pedestrian trajectories is crucial for improving the safety of autonomous driving. However, this task is generally nontrivial due to the inherent stochasticity of human motion, which naturally requires the predictor…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Ge Sun , Sheng Wang , Lei Zhu , Ming Liu , Jun Ma

Diffusion Models represent a significant advancement in generative modeling, employing a dual-phase process that first degrades domain-specific information via Gaussian noise and restores it through a trainable model. This framework enables…

Neural and Evolutionary Computing · Computer Science 2024-11-21 Benedikt Hartl , Yanbo Zhang , Hananel Hazan , Michael Levin

Known for their impressive performance in generative modeling, diffusion models are attractive candidates for density-based anomaly detection. This paper investigates different variations of diffusion modeling for unsupervised and…

Machine Learning · Computer Science 2026-05-11 Victor Livernoche , Vineet Jain , Yashar Hezaveh , Siamak Ravanbakhsh

We study the problem of learning a neural sampler to generate samples from discrete state spaces where the target probability mass function $\pi\propto\mathrm{e}^{-U}$ is known up to a normalizing constant, which is an important task in…

Machine Learning · Computer Science 2025-11-11 Yuchen Zhu , Wei Guo , Jaemoo Choi , Guan-Horng Liu , Yongxin Chen , Molei Tao

Negative Prompting (NP) is widely utilized in diffusion models, particularly in text-to-image applications, to prevent the generation of undesired features. In this paper, we show that conventional NP is limited by the assumption of a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Felix Koulischer , Johannes Deleu , Gabriel Raya , Thomas Demeester , Luca Ambrogioni

Score-based diffusion models, which generate new data by learning to reverse a diffusion process that perturbs data from the target distribution into noise, have achieved remarkable success across various generative tasks. Despite their…

Machine Learning · Computer Science 2025-01-23 Gen Li , Yuling Yan

This paper explores the utility of diffusion-based models for anomaly detection, focusing on their efficacy in identifying deviations in both compact and high-resolution datasets. Diffusion-based architectures, including Denoising Diffusion…

Machine Learning · Computer Science 2024-12-11 Aryan Bhosale , Samrat Mukherjee , Biplab Banerjee , Fabio Cuzzolin

We introduce the Fixed Point Diffusion Model (FPDM), a novel approach to image generation that integrates the concept of fixed point solving into the framework of diffusion-based generative modeling. Our approach embeds an implicit fixed…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Xingjian Bai , Luke Melas-Kyriazi

Image denoising is a fundamental and challenging task in the field of computer vision. Most supervised denoising methods learn to reconstruct clean images from noisy inputs, which have intrinsic spectral bias and tend to produce…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Yujin Wang , Lingen Li , Tianfan Xue , Jinwei Gu

Signal peptide (SP) is a short peptide located in the N-terminus of proteins. It is essential to target and transfer transmembrane and secreted proteins to correct positions. Compared with traditional experimental methods to identify signal…

Artificial Intelligence · Computer Science 2023-12-15 Junbo Shen , Qinze Yu , Shenyang Chen , Qingxiong Tan , Jingcheng Li , Yu Li

Supervised deep learning methods have shown promise in undersampled Magnetic Resonance Imaging (MRI) reconstruction, but their requirement for paired data limits their generalizability to the diverse MRI acquisition parameters. Recently,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Wei Jiang , Zhuang Xiong , Feng Liu , Nan Ye , Hongfu Sun

Diffusion inversion is a task of recovering the noise of an image in a diffusion model, which is vital for controllable diffusion image editing. At present, diffusion inversion still remains a challenging task due to the lack of viable…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Ziyue Zhang , Luxi Lin , Xiaolin Hu , Chao Chang , HuaiXi Wang , Yiyi Zhou , Rongrong Ji