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Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

Recently, methods based on deep learning have been successfully applied to ship detection for synthetic aperture radar (SAR) images. Despite the development of numerous ship detection methodologies, detecting small and coastal ships remains…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Xiaolin Ma , Junkai Cheng , Aihua Li , Yuhua Zhang , Zhilong Lin

Despite significant progress of deep learning in recent years, state-of-the-art semantic matching methods still rely on legacy features such as SIFT or HoG. We argue that the strong invariance properties that are key to the success of…

Computer Vision and Pattern Recognition · Computer Science 2017-04-18 David Novotny , Diane Larlus , Andrea Vedaldi

Foundation models have recently emerged as powerful feature extractors in computational pathology, yet they typically omit mechanisms for leveraging the global spatial structure of tissues and the local contextual relationships among…

Whole Slide Images (WSI), obtained by high-resolution digital scanning of microscope slides at multiple scales, are the cornerstone of modern Digital Pathology. However, they represent a particular challenge to AI-based/AI-mediated analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Martim Afonso , Praphulla M. S. Bhawsar , Monjoy Saha , Jonas S. Almeida , Arlindo L. Oliveira

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Multiple Instance Learning (MIL) represents the predominant framework in Whole Slide Image (WSI) classification, covering aspects such as sub-typing, diagnosis, and beyond. Current MIL models predominantly rely on instance-level features…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Heng Fang , Sheng Huang , Wenhao Tang , Luwen Huangfu , Bo Liu

We introduce the attention-indexed model (AIM), a theoretical framework for analyzing learning in deep attention layers. Inspired by multi-index models, AIM captures how token-level outputs emerge from layered bilinear interactions over…

Machine Learning · Computer Science 2026-02-03 Fabrizio Boncoraglio , Emanuele Troiani , Vittorio Erba , Lenka Zdeborová

Convolutional networks (ConvNets) have achieved promising accuracy for various anatomical segmentation tasks. Despite the success, these methods can be sensitive to data appearance variations. Considering the large variability of scans…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Yuan Liang , Weinan Song , Jiawei Yang , Liang Qiu , Kun Wang , Lei He

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Visual place recognition (VPR) is one of the research hotspots in robotics, which uses visual information to locate robots. Recently, the hierarchical two-stage VPR methods have become popular in this field due to the trade-off between…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Feng Lu , Lijun Zhang , Shuting Dong , Baifan Chen , Chun Yuan

The whole slide image (WSI) classification is often formulated as a multiple instance learning (MIL) problem. Since the positive tissue is only a small fraction of the gigapixel WSI, existing MIL methods intuitively focus on identifying…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenhao Tang , Sheng Huang , Xiaoxian Zhang , Fengtao Zhou , Yi Zhang , Bo Liu

Cancer is an abnormal growth with potential to invade locally and metastasize to distant organs. Accurate auto-segmentation of the tumor and surrounding normal tissues is required for radiotherapy treatment plan optimization. Recent…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Syed Haider Ali , Asrar Ahmad , Muhammad Ali , Asifullah Khan , Nadeem Shaukat

One way to extract patterns from clinical records is to consider each patient record as a bag with various number of instances in the form of symptoms. Medical diagnosis is to discover informative ones first and then map them to one or more…

Machine Learning · Computer Science 2019-04-10 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Instance-level alignment is widely exploited for person re-identification, e.g. spatial alignment, latent semantic alignment and triplet alignment. This paper probes another feature alignment modality, namely cluster-level feature alignment…

Computer Vision and Pattern Recognition · Computer Science 2020-08-18 Qiuyu Chen , Wei Zhang , Jianping Fan

In medical real-world study (RWS), how to fully utilize the fragmentary and scarce information in model training to generate the solid diagnosis results is a challenging task. In this work, we introduce a novel multi-instance neural…

Machine Learning · Computer Science 2019-07-04 Zeyuan Wang , Josiah Poon , Simon Poon

In response to the worldwide COVID-19 pandemic, advanced automated technologies have emerged as valuable tools to aid healthcare professionals in managing an increased workload by improving radiology report generation and prognostic…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Zhusi Zhong , Jie Li , John Sollee , Scott Collins , Harrison Bai , Paul Zhang , Terrence Healey , Michael Atalay , Xinbo Gao , Zhicheng Jiao

Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…

Mammogram classification is directly related to computer-aided diagnosis of breast cancer. Traditional methods rely on regions of interest (ROIs) which require great efforts to annotate. Inspired by the success of using deep convolutional…

Computer Vision and Pattern Recognition · Computer Science 2017-05-25 Wentao Zhu , Qi Lou , Yeeleng Scott Vang , Xiaohui Xie

Existing few-shot segmentation methods are based on the meta-learning strategy and extract instance knowledge from a support set and then apply the knowledge to segment target objects in a query set. However, the extracted knowledge is…

Computer Vision and Pattern Recognition · Computer Science 2023-05-24 Yong Yang , Qiong Chen , Yuan Feng , Tianlin Huang
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