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Large Language Model (LLMs) such as ChatGPT that exhibit generative AI capabilities are facing accelerated adoption and innovation. The increased presence of Generative AI (GAI) inevitably raises concerns about the risks and safety…

Computers and Society · Computer Science 2024-07-29 Jaymari Chua , Yun Li , Shiyi Yang , Chen Wang , Lina Yao

Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained…

Artificial Intelligence · Computer Science 2025-11-07 Jiahao Zhao , Luxin Xu , Minghuan Tan , Lichao Zhang , Ahmadreza Argha , Hamid Alinejad-Rokny , Min Yang

Evaluating Large Language Models (LLMs) for mental health support is challenging due to the emotionally and cognitively complex nature of therapeutic dialogue. Existing benchmarks are limited in scale, reliability, often relying on…

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

We present a comprehensive evaluation framework for assessing Large Language Models' (LLMs) capabilities in suicide prevention, focusing on two critical aspects: the Identification of Implicit Suicidal ideation (IIS) and the Provision of…

Computation and Language · Computer Science 2026-01-14 Tong Li , Shu Yang , Junchao Wu , Jiyao Wei , Lijie Hu , Mengdi Li , Derek F. Wong , Joshua R. Oltmanns , Di Wang

We introduce findings and methods to facilitate evidence-based discussion about how large language models (LLMs) should behave in response to user signals of risk of suicidal thoughts and behaviors (STB). People are already using LLMs as…

Human-Computer Interaction · Computer Science 2025-11-03 Nick Judd , Alexandre Vaz , Kevin Paeth , Layla Inés Davis , Milena Esherick , Jason Brand , Inês Amaro , Tony Rousmaniere

In response to the increasing mental health challenges faced by college students, we sought to understand their perspectives on how AI applications, particularly Large Language Models (LLMs), can be leveraged to enhance their mental…

Human-Computer Interaction · Computer Science 2024-09-27 Owen Xingjian Zhang , Shuyao Zhou , Jiayi Geng , Yuhan Liu , Sunny Xun Liu

Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come…

Computation and Language · Computer Science 2024-08-02 Hannah R. Lawrence , Renee A. Schneider , Susan B. Rubin , Maja J. Mataric , Daniel J. McDuff , Megan Jones Bell

Recent advancements in large language models (LLMs) promise to expand mental health interventions by emulating therapeutic techniques, potentially easing barriers to care. Yet there is a lack of real-world empirical evidence evaluating the…

Human-Computer Interaction · Computer Science 2025-01-28 Yinzhou Wang , Yimeng Wang , Ye Xiao , Liabette Escamilla , Bianca Augustine , Kelly Crace , Gang Zhou , Yixuan Zhang

Red-teaming is a core part of the infrastructure that ensures that AI models do not produce harmful content. Unlike past technologies, the black box nature of generative AI systems necessitates a uniquely interactional mode of testing, one…

The emergence of generative AI chatbots such as ChatGPT has prompted growing public and academic interest in their role as informal mental health support tools. While early rule-based systems have been around for several years, large…

Computation and Language · Computer Science 2025-04-18 Anna-Carolina Haensch

Recent advancements in artificial intelligence (AI), particularly in large language models (LLMs), have unlocked significant potential to enhance the quality and efficiency of medical care. By introducing a novel way to interact with AI and…

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

The proliferation of Large Language Models (LLMs) has intensified concerns about manipulative or deceptive behaviors that can undermine user autonomy, trust, and well-being. Existing safety benchmarks predominantly rely on coarse binary…

Artificial Intelligence · Computer Science 2025-12-30 Sadia Asif , Israel Antonio Rosales Laguan , Haris Khan , Shumaila Asif , Muneeb Asif

LGBTQ+ community face disproportionate mental health challenges, including higher rates of depression, anxiety, and suicidal ideation. Research has shown that LGBTQ+ people have been using large language model-based chatbots, such as…

Human-Computer Interaction · Computer Science 2024-05-09 Yinru Long , Zilin Ma , Yiyang Mei , Zhaoyuan Su

Psychological support hotlines serve as critical lifelines for crisis intervention but encounter significant challenges due to rising demand and limited resources. Large language models (LLMs) offer potential support in crisis assessments,…

Computation and Language · Computer Science 2025-12-19 Guifeng Deng , Shuyin Rao , Tianyu Lin , Anlu Dai , Pan Wang , Junyi Xie , Haidong Song , Ke Zhao , Dongwu Xu , Zhengdong Cheng , Tao Li , Haiteng Jiang

Large language models (LLMs) are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned, particularly in sensitive or high-risk contexts. Existing…

Human-Computer Interaction · Computer Science 2026-01-21 Jiwon Kim , Violeta J. Rodriguez , Dong Whi Yoo , Eshwar Chandrasekharan , Koustuv Saha

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

Larger language models (LLMs) have taken the world by storm with their massive multi-tasking capabilities simply by optimizing over a next-word prediction objective. With the emergence of their properties and encoded knowledge, the risk of…

Computation and Language · Computer Science 2023-08-31 Rishabh Bhardwaj , Soujanya Poria