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Precision rehabilitation offers the promise of an evidence-based approach for optimizing individual rehabilitation to improve long-term functional outcomes. Emerging techniques, including those driven by artificial intelligence, are rapidly…

Quantitative Methods · Quantitative Biology 2024-11-07 R. James Cotton , Bryant A. Seamon , Richard L. Segal , Randal D. Davis , Amrita Sahu , Michelle M. McLeod , Pablo Celnik , Sharon L. Ramey

Causal decomposition has provided a powerful tool to analyze health disparity problems, by assessing the proportion of disparity caused by each mediator. However, most of these methods lack \emph{policy implications}, as they fail to…

Methodology · Statistics 2023-02-21 Xinwei Sun , Xiangyu Zheng , Jim Weinstein

Efficiently navigating complex environments requires agents to internalize the underlying logic of their world, yet standard world modelling methods often struggle with sample inefficiency, lack of transparency, and poor scalability. We…

Artificial Intelligence · Computer Science 2026-02-20 Enrique Crespo-Fernandez , Oliver Ray , Telmo de Menezes e Silva Filho , Peter Flach

A common practice in unsupervised representation learning is to use labeled data to evaluate the quality of the learned representations. This supervised evaluation is then used to guide critical aspects of the training process such as…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Colorado J Reed , Sean Metzger , Aravind Srinivas , Trevor Darrell , Kurt Keutzer

Causal mediation analysis aims at disentangling a treatment effect into an indirect mechanism operating through an intermediate outcome or mediator, as well as the direct effect of the treatment on the outcome of interest. However, the…

Econometrics · Economics 2020-05-05 Martin Huber , Lukáš Lafférs

Mediation analysis in causal inference has traditionally focused on binary exposures and deterministic interventions, and a decomposition of the average treatment effect in terms of direct and indirect effects. In this paper we present an…

Methodology · Statistics 2020-11-17 Iván Díaz , Nima Hejazi

We study causal effect estimation from a mixture of observational and interventional data in a confounded linear regression model with multivariate treatments. We show that the statistical efficiency in terms of expected squared error can…

Causal mediation analysis can improve understanding of the mechanisms underlying epidemiologic associations. However, the utility of natural direct and indirect effect estimation has been limited by the assumption of no confounder of the…

Applications · Statistics 2020-06-16 Kara E. Rudolph , Oleg Sofrygin , Wenjing Zheng , Mark J. van der Laan

Assessing causal effects in the presence of unobserved confounding is a challenging problem. Existing studies leveraged proxy variables or multiple treatments to adjust for the confounding bias. In particular, the latter approach attributes…

Methodology · Statistics 2023-10-17 Yong Wu , Mingzhou Liu , Jing Yan , Yanwei Fu , Shouyan Wang , Yizhou Wang , Xinwei Sun

Unlike classical causal inference, which often has an average causal effect of a treatment within a population as a target, in settings such as personalized medicine, the goal is to map a given unit's characteristics to a treatment tailored…

Methodology · Statistics 2017-09-13 Ilya Shpitser , Sourjya Sarkar

Policy evaluation in empirical microeconomics has been focusing on estimating the average treatment effect and more recently the heterogeneous treatment effects, often relying on the unconfoundedness assumption. We propose a method based on…

Econometrics · Economics 2023-06-06 Wei Tian

Off-policy evaluation is a key component of reinforcement learning which evaluates a target policy with offline data collected from behavior policies. It is a crucial step towards safe reinforcement learning and has been used in…

Machine Learning · Computer Science 2020-12-01 Jinlin Lai , Lixin Zou , Jiaxing Song

A common concern when a policymaker draws causal inferences from and makes decisions based on observational data is that the measured covariates are insufficiently rich to account for all sources of confounding, i.e., the standard no…

Methodology · Statistics 2023-10-25 Tao Shen , Yifan Cui

In Influence Maximization (IM), the objective is to -- given a budget -- select the optimal set of entities in a network to target with a treatment so as to maximize the total effect. For instance, in marketing, the objective is to target…

Social and Information Networks · Computer Science 2025-06-05 Daan Caljon , Jente Van Belle , Jeroen Berrevoets , Wouter Verbeke

Meta-analysis is commonly used to combine results from multiple clinical trials, but traditional meta-analysis methods do not refer explicitly to a population of individuals to whom the results apply and it is not clear how to use their…

We consider the task of optimizing treatment assignment based on individual treatment effect prediction. This task is found in many applications such as personalized medicine or targeted advertising and has gained a surge of interest in…

Machine Learning · Computer Science 2020-12-21 Artem Betlei , Eustache Diemert , Massih-Reza Amini

In observational studies, balancing covariates in different treatment groups is essential to estimate treatment effects. One of the most commonly used methods for such purposes is weighting. The performance of this class of methods usually…

Methodology · Statistics 2021-07-07 Ruoqi Yu , Shulei Wang

Many marketing applications, including credit card incentive programs, offer rewards to customers who exceed specific spending thresholds to encourage increased consumption. Quantifying the causal effect of these thresholds on customers is…

Methodology · Statistics 2026-01-19 Kohsuke Kubota , Shonosuke Sugasawa

By adhering to the dictum, "No causation without manipulation (treatment, intervention)", cause and effect data analysis represents changes in observed data in terms of changes in the causal factors. When causal factors are not amenable for…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 M. Alex O. Vasilescu , Eric Kim , Xiao S. Zeng

Modeling policies for sequential clinical decision-making based on observational data is useful for describing treatment practices, standardizing frequent patterns in treatment, and evaluating alternative policies. For each task, it is…

Machine Learning · Computer Science 2024-12-12 Anton Matsson , Lena Stempfle , Yaochen Rao , Zachary R. Margolin , Heather J. Litman , Fredrik D. Johansson
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