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In this paper, we propose generating synthetic multiple sclerosis (MS) lesions on MRI images with the final aim to improve the performance of supervised machine learning algorithms, therefore avoiding the problem of the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2019-01-18 Mostafa Salem , Sergi Valverde , Mariano Cabezas , Deborah Pareto , Arnau Oliver , Joaquim Salvi , Àlex Rovira , Xavier Lladó

In the realm of smart healthcare, researchers enhance the scale and diversity of medical datasets through medical image synthesis. However, existing methods are limited by CNN local perception and Transformer quadratic complexity, making it…

Image and Video Processing · Electrical Eng. & Systems 2024-05-10 Zhihan Ju , Wanting Zhou

Self-supervised learning is an efficient pre-training method for medical image analysis. However, current research is mostly confined to specific-modality data pre-training, consuming considerable time and resources without achieving…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Qi Wu , Yong Xia

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Johanna P. Müller , Anika Knupfer , Pedro Blöss , Edoardo Berardi Vittur , Bernhard Kainz , Jana Hutter

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

Machine Learning · Computer Science 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

The use of synthetic data has emerged as an essential tool in Magnetic Resonance Spectroscopy (MRS) research and applications, providing advantages for optimization of acquisition, software validation, deep learning applications, and…

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

Magnetic Resonance (MR) images of different modalities can provide complementary information for clinical diagnosis, but whole modalities are often costly to access. Most existing methods only focus on synthesizing missing images between…

Computer Vision and Pattern Recognition · Computer Science 2020-05-05 Bingyu Xin , Yifan Hu , Yefeng Zheng , Hongen Liao

Segmenting stroke lesions in MRI is challenging due to diverse acquisition protocols that limit model generalisability. In this work, we introduce two physics-constrained approaches to generate synthetic quantitative MRI (qMRI) images that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

In clinical practice, full imaging is not always feasible, often due to complex acquisition protocols, stringent privacy regulations, or specific clinical needs. However, missing MR modalities pose significant challenges for tasks like…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Dealing with missing modalities in Magnetic Resonance Imaging (MRI) and overcoming their negative repercussions is considered a hurdle in biomedical imaging. The combination of a specified set of modalities, which is selected depending on…

Image and Video Processing · Electrical Eng. & Systems 2022-03-15 Reza Azad , Nika Khosravi , Mohammad Dehghanmanshadi , Julien Cohen-Adad , Dorit Merhof

Magnetic Resonance Imaging (MRI) field-strength enhancement holds immense value for both clinical diagnostics and advanced research. However, existing methods typically focus on isolated enhancement tasks, such as specific 64mT-to-3T or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Yiyang Lin , Chenhui Wang , Zhihao Peng , Yixuan Yuan

Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…

Medical Physics · Physics 2023-10-31 Dinor Nagar , Nikita Vladimirov , Christian T. Farrar , Or Perlman

We present a tool for resolution recovery in multimodal clinical magnetic resonance imaging (MRI). Such images exhibit great variability, both biological and instrumental. This variability makes automated processing with neuroimaging…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Mikael Brudfors , Yael Balbastre , Parashkev Nachev , John Ashburner

Recently, medical image synthesis gains more and more popularity, along with the rapid development of generative models. Medical image synthesis aims to generate an unacquired image modality, often from other observed data modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-04 Zhe Xiong , Qiaoqiao Ding , Xiaoqun Zhang

Magnetic Resonance Imaging (MRI) is instrumental in clinical diagnosis, offering diverse contrasts that provide comprehensive diagnostic information. However, acquiring multiple MRI contrasts is often constrained by high costs, long…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Sanuwani Dayarathna , Kh Tohidul Islam , Bohan Zhuang , Guang Yang , Jianfei Cai , Meng Law , Zhaolin Chen

Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Qinqin Yang , Firoozeh Shomal-Zadeh , Ali Gholipour

Multimodal Magnetic Resonance (MR) Imaging plays a crucial role in disease diagnosis due to its ability to provide complementary information by analyzing a relationship between multimodal images on the same subject. Acquiring all MR…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jihoon Cho , Xiaofeng Liu , Fangxu Xing , Jinsong Ouyang , Georges El Fakhri , Jinah Park , Jonghye Woo

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang
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