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Large language models (LLMs) have achieved great success in medical question answering and clinical decision-making, promoting the efficiency and popularization of the personalized virtual doctor in society. However, the traditional…

Computation and Language · Computer Science 2025-09-23 Jianbin Zhang , Yulin Zhu , Wai Lun Lo , Richard Tai-Chiu Hsung , Harris Sik-Ho Tsang , Kai Zhou

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

Electronic Health Records (EHRs) provide high-dimensional temporal data essential for patient modeling; however, conventional algorithmic approaches often rely on data aggregation or imputation, which distorts temporal disease trajectories.…

Machine Learning · Computer Science 2026-04-21 Pi-Ju Tsai , Charkkri Limbud , Kuan-Fu Chen , Yi-Ju Tseng

Electronic Health Records (EHRs) provide a rich, longitudinal view of patient health and hold significant potential for advancing clinical decision support, risk prediction, and data-driven healthcare research. However, most artificial…

In longitudinal electronic health records (EHRs), the event records of a patient are distributed over a long period of time and the temporal relations between the events reflect sufficient domain knowledge to benefit prediction tasks such…

Computation and Language · Computer Science 2020-06-16 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang , Michael Blumenstein

Electronic health records (EHRs), digital collections of patient healthcare events and observations, are ubiquitous in medicine and critical to healthcare delivery, operations, and research. Despite this central role, EHRs are notoriously…

Researchers require timely access to real-world longitudinal electronic health records (EHR) to develop, test, validate, and implement machine learning solutions that improve the quality and efficiency of healthcare. In contrast, health…

Machine Learning · Computer Science 2020-12-21 Siddharth Biswal , Soumya Ghosh , Jon Duke , Bradley Malin , Walter Stewart , Jimeng Sun

Transformer-based deep learning models have shown promise for disease risk prediction using electronic health records(EHRs), but modeling temporal dependencies remains a key challenge due to irregular visit intervals and lack of uniform…

Machine Learning · Computer Science 2025-11-10 Daniel S. Lee , Mayra S. Haedo-Cruz , Chen Jiang , Oshin Miranda , LiRong Wang

EHR systems lack a unified code system forrepresenting medical concepts, which acts asa barrier for the deployment of deep learningmodels in large scale to multiple clinics and hos-pitals. To overcome this problem, we…

Computation and Language · Computer Science 2022-01-19 Kyunghoon Hur , Jiyoung Lee , Jungwoo Oh , Wesley Price , Young-Hak Kim , Edward Choi

Electronic health records (EHR) even though a boon for healthcare practitioners, are growing convoluted and longer every day. Sifting around these lengthy EHRs is taxing and becomes a cumbersome part of physician-patient interaction.…

Computation and Language · Computer Science 2024-04-26 Saranya Krishnamoorthy , Ayush Singh , Shabnam Tafreshi

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

Understanding patients' journeys in healthcare system is a fundamental prepositive task for a broad range of AI-based healthcare applications. This task aims to learn an informative representation that can comprehensively encode hidden…

Machine Learning · Computer Science 2020-06-22 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang

Synthetic electronic health records (EHRs) that are both realistic and preserve privacy can serve as an alternative to real EHRs for machine learning (ML) modeling and statistical analysis. However, generating high-fidelity and granular…

Machine Learning · Computer Science 2023-11-13 Brandon Theodorou , Cao Xiao , Jimeng Sun

In this work we addressed the problem of capturing sequential information contained in longitudinal electronic health records (EHRs). Clinical notes, which is a particular type of EHR data, are a rich source of information and practitioners…

Computation and Language · Computer Science 2020-10-27 Andrey Kormilitzin , Nemanja Vaci , Qiang Liu , Hao Ni , Goran Nenadic , Alejo Nevado-Holgado

Retrieving temporal event sequences from textual descriptions is crucial for applications such as analyzing e-commerce behavior, monitoring social media activities, and tracking criminal incidents. To advance this task, we introduce…

Computation and Language · Computer Science 2025-02-04 Zefang Liu , Yinzhu Quan

By processing electronic health records (EHRs) as natural language sequences, large language models (LLMs) have shown potential in clinical prediction tasks such as mortality prediction and phenotyping. However, longitudinal or highly…

Computation and Language · Computer Science 2026-05-13 Mingcheng Zhu , Zhiyao Luo , Yu Liu , Tingting Zhu

Electronic Health Records (EHR) have revolutionized healthcare by digitizing patient data, improving accessibility, and streamlining clinical workflows. However, extracting meaningful insights from these complex and multimodal datasets…

Artificial Intelligence · Computer Science 2025-10-27 Naama Kashani , Mira Cohen , Uri Shaham

Many real-world Electronic Health Record (EHR) data contains a large proportion of missing values. Leaving substantial portion of missing information unaddressed usually causes significant bias, which leads to invalid conclusion to be…

Machine Learning · Computer Science 2020-11-04 Lucas J. Liu , Hongwei Zhang , Jianzhong Di , Jin Chen