Related papers: PaReGTA: An LLM-based EHR Data Encoding Approach t…
Electronic health record (EHR) data are increasingly used to support real-world evidence (RWE) studies. Yet its ability to generate reliable RWE is limited by the lack of readily available precise information on the timing of clinical…
Electronic Health Records (EHRs) contain a large volume of heterogeneous patient data, which are useful at the point of care and for retrospective research. These data are typically stored in relational databases. Gaining an integrated view…
Electronic health records (EHR) contain valuable longitudinal patient-level information, yet most statistical methods reduce the irregular timing of EHR codes into simple counts, thereby discarding rich temporal structure. Existing temporal…
Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this…
Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…
The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…
Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…
The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…
Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…
Medical activities, such as diagnoses, medicine treatments, and laboratory tests, as well as temporal relations between these activities are the basic concepts in clinical research. However, existing relational data model on electronic…
Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…
Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…
Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…
Large language models (LLMs) have demonstrated exceptional capabilities in planning and tool utilization as autonomous agents, but few have been developed for medical problem-solving. We propose EHRAgent, an LLM agent empowered with a code…
Longitudinal electronic health record (EHR) data offer opportunities to study biomarker trajectories; however, association estimates-the primary inferential target-from standard models designed for regular observation times may be biased by…
Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…
Structured Electronic Health Record (EHR) data stores patient information in relational tables and plays a central role in clinical decision-making. Recent advances have explored the use of large language models (LLMs) to process such data,…
The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…
Electronic Health Records (EHR) can be represented as temporal sequences that record the events (medical visits) from patients. Neural temporal point process (NTPP) has achieved great success in modeling event sequences that occur in…
Medical consultation dialogues contain critical clinical information, yet their unstructured nature hinders effective utilization in diagnosis and treatment. Traditional methods, relying on rule-based or shallow machine learning techniques,…