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Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

Propagation-based X-ray phase-contrast imaging (PBI) enables high-contrast visualization of lung structures and holds strong medical potential. However, safe translation to the clinic will require a substantial radiation dose reduction,…

Image denoising of low-dose computed tomography (LDCT) is an important problem for clinical diagnosis with reduced radiation exposure. Previous methods are mostly trained with pairs of synthetic or misaligned LDCT and normal-dose CT (NDCT)…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Junhao Long , Fengwei Yang , Juncheng Yan , Baoping Zhang , Chao Jin , Jian Yang , Changliang Zou , Jun Xu

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

Deep learning is a very promising technique for low-dose computed tomography (LDCT) image denoising. However, traditional deep learning methods require paired noisy and clean datasets, which are often difficult to obtain. This paper…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Yuting Zhu , Qiang He , Yudong Yao , Yueyang Teng

Image denoising is a fundamental problem in computer vision and medical imaging. However, real-world images are often degraded by structured noise with strong anisotropic correlations that existing methods struggle to remove. Most…

Image and Video Processing · Electrical Eng. & Systems 2025-10-03 Jianxu Wang , Ge Wang

Real-world image denoising is an extremely important image processing problem, which aims to recover clean images from noisy images captured in natural environments. In recent years, diffusion models have achieved very promising results in…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Cheng Yang , Lijing Liang , Zhixun Su

The resurgence of deep neural networks has created an alternative pathway for low-dose computed tomography denoising by learning a nonlinear transformation function between low-dose CT (LDCT) and normal-dose CT (NDCT) image pairs. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Sutanu Bera , Prabir Kumar Biswas

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Image denoising is a fundamental challenge in computer vision, with applications in photography and medical imaging. While deep learning-based methods have shown remarkable success, their reliance on specific noise distributions limits…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Dongjin Kim , Jaekyun Ko , Muhammad Kashif Ali , Tae Hyun Kim

Noise in low-dose computed tomography (LDCT) can obscure important diagnostic details. While deep learning offers powerful denoising, supervised methods require impractical paired data, and self-supervised alternatives often use opaque,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Yipeng Sun , Linda-Sophie Schneider , Siyuan Mei , Jinhua Wang , Ge Hu , Mingxuan Gu , Chengze Ye , Fabian Wagner , Lan Song , Siming Bayer , Andreas Maier

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

In this paper, we propose a novel image denoising algorithm exploiting features from both spatial as well as transformed domain. We implement intensity-invariance based improved grouping for collaborative support-agnostic sparse…

Computer Vision and Pattern Recognition · Computer Science 2018-05-03 Muzammil Behzad

Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Jitindra Fartiyal , Pedro Freire , Sergei K. Turitsyn , Sergei G. Solovski

Biomedical images are noisy. The imaging equipment itself has physical limitations, and the consequent experimental trade-offs between signal-to-noise ratio, acquisition speed, and imaging depth exacerbate the problem. Denoising is,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Mikhail Papkov , Kenny Roberts , Lee Ann Madissoon , Omer Bayraktar , Dmytro Fishman , Kaupo Palo , Leopold Parts

The field of image denoising is currently dominated by discriminative deep learning methods that are trained on pairs of noisy input and clean target images. Recently it has been shown that such methods can also be trained without clean…

Computer Vision and Pattern Recognition · Computer Science 2019-04-08 Alexander Krull , Tim-Oliver Buchholz , Florian Jug

In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

Medical Physics · Physics 2022-04-12 Long Zhou , Xiaozhuang Wang , Min Hou , Ping Li , Chunlong Fu , Yanjun Ren , Tingting Shao , Xi Hu , Jihong Sun , Hongwei Ye

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang
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