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Quantum simulations of molecular systems on quantum computers often employ minimal basis sets of Gaussian orbitals. In comparison with more realistic basis sets, quantum simulations employing minimal basis sets require fewer qubits and…

Quantum Physics · Physics 2022-08-17 Stefano Barison , Davide Emilio Galli , Mario Motta

Mainstream machine-learning techniques such as deep learning and probabilistic programming rely heavily on sampling from generally intractable probability distributions. There is increasing interest in the potential advantages of using…

Quantum Physics · Physics 2018-01-29 Marcello Benedetti , John Realpe-Gómez , Rupak Biswas , Alejandro Perdomo-Ortiz

The quantum thermal average plays a central role in describing the thermodynamic properties of a quantum system. Path integral molecular dynamics (PIMD) is a prevailing approach for computing quantum thermal averages by approximating the…

Numerical Analysis · Mathematics 2024-06-25 Xuda Ye , Zhennan Zhou

Quantum computers hold promise to enable efficient simulations of the properties of molecules and materials; however, at present they only permit ab initio calculations of a few atoms, due to a limited number of qubits. In order to harness…

Materials Science · Physics 2020-07-07 He Ma , Marco Govoni , Giulia Galli

An accurate treatment of the structures and dynamics that lead to enhanced chemical reactivity in enzymes requires explicit treatment of both electronic and nuclear quantum effects. The former can be captured in ab initio molecular dynamics…

Chemical Physics · Physics 2022-08-26 Lu Wang , Christine M. Isborn , Thomas E. Markland

Quantum geometrical molecular dynamics provides a quantum geometric picture for understanding reactive dynamics, especially excited-state conical intersection dynamics, and also a numerically exact method for strongly correlated…

Chemical Physics · Physics 2026-01-26 Mo Sha , Bing Gu

We introduce a straightforward numerical coarse-graining scheme to estimate quantum states for a set of noisy measurement outcomes, which are difficult to calibrate, that is based solely on the measurement data collected from these…

Quantum Physics · Physics 2013-08-15 Yong Siah Teo , Jaroslav Rehacek , Zdenek Hradil

The uniform electron gas (UEG) at finite temperature has recently attracted substantial interest due to the epxerimental progress in the field of warm dense matter. To explain the experimental data accurate theoretical models for high…

Strongly Correlated Electrons · Physics 2015-03-25 V. S. Filinov , V. E. Fortov , M. Bonitz , Zh. Moldabekov

A generalized understanding of protein dynamics is an unsolved scientific problem, the solution of which is critical to the interpretation of the structure-function relationships that govern essential biological processes. Here, we approach…

The development and implementation of increasingly accurate methods for electronic structure calculations mean that, for many atomistic simulation problems, treating light nuclei as classical particles is now one of the most serious…

Materials Science · Physics 2016-02-12 Venkat Kapil , Joost VandeVondele , Michele Ceriotti

We study nanomachines whose relevant (effective) degrees of freedom f >> 1 but smaller than f of proteins. In these machines, both the entropic and the quantum effects over the whole system play the essential roles in producing nontrivial…

Mesoscale and Nanoscale Physics · Physics 2020-05-20 Ryoko Hatakeyama , Akira Shimizu

Accurate simulation of nuclear quantum effects is essential for molecular modeling but expensive using path integral molecular dynamics (PIMD). We present GG-PI, a ring-polymer-based framework that combines generative modeling of the…

Chemical Physics · Physics 2026-01-29 Weizhou Wang , Xuanxi Zhang , Jonathan Weare , Aaron R. Dinner

In the present article, novel Coarse-Graining (CG) algorithms for the Eulerian-Lagrangian (EL) simulation of particle-laden flows are proposed. These include different variants of Reproducing Kernel Particle Methods (RKPM) and an extended…

Fluid Dynamics · Physics 2025-11-12 H. Eshraghi , E. Amani , M. Saffar-Avval

We report the implementation of a multi-CPU and multi-GPU massively parallel platform dedicated to the explicit inclusion of nuclear quantum effects (NQEs) in the Tinker-HP molecular dynamics (MD) package. The platform, denoted Quantum-HP,…

To take into account nuclear quantum effects on the dynamics of atoms, the path integral molecular dynamics (PIMD) method used since 1980s is based on the formalism developed by R. P. Feynman. However, the huge computation time required for…

Computational Physics · Physics 2019-05-08 H. Dammak , M. Hayoun , F Brieuc , G. Geneste

The problem of simulating the thermal behavior of quantum systems remains a central open challenge in quantum computing. Unlike well-established quantum algorithms for unitary dynamics, \emph{provably efficient} algorithms for preparing…

Quantum Physics · Physics 2026-05-14 Dominik Hahn , Ryan Sweke , Abhinav Deshpande , Oles Shtanko

Proton-coupled electron transfer (PCET) is the key step for energy conversion in electrocatalysis. Atomic-scale simulation acts as an indispensable tool to provide a microscopic understanding of PCET. However, consideration of the quantum…

Materials Science · Physics 2024-08-27 Menglin Sun , Bin Jin , Xiaolong Yang , Shenzhen Xu

It is by now well-known that ground states of gapped one-dimensional (1d) quantum-many body systems with short-range interactions can be studied efficiently using classical computers and matrix product state techniques. A corresponding…

Quantum Physics · Physics 2017-08-31 Thomas Barthel

Recent developments in path integral methodology have significantly reduced the computational expense of including quantum mechanical effects in the nuclear motion in ab initio molecular dynamics simulations. However, the implementation of…

Computational Physics · Physics 2014-02-06 Michele Ceriotti , Joshua More , David E. Manolopoulos

In the research of condensed matter, atomistic dynamic simulations play a crucial role, particularly in revealing dynamic processes, phase transitions and thermodynamic statistics macroscopic physical properties in systems such as solids…

Materials Science · Physics 2025-05-30 Hongyu Wu , Wenliang Shi , Ri He , Guoyong Shi , Chunxiao Zhang , Zhicheng Zhong , Run-wei Li