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From the complex motions of robots to the oxygen binding of hemoglobin, the function of many mechanical systems depends on large, coordinated movements of their components. Such movements arise from a network of physical interactions in the…

Soft Condensed Matter · Physics 2019-06-21 Jason Z. Kim , Zhixin Lu , Danielle S. Bassett

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Cell differentiation in multicellular organisms is a complex process whose mechanism can be understood by a reductionist approach, in which the individual processes that control the generation of different cell types are identified.…

In complex inferential tasks like question answering, machine learning models must confront two challenges: the need to implement a compositional reasoning process, and, in many applications, the need for this reasoning process to be…

Computer Vision and Pattern Recognition · Computer Science 2019-03-08 Ronghang Hu , Jacob Andreas , Trevor Darrell , Kate Saenko

Recent advances in machine learning have dramatically improved our ability to model language, vision, and other high-dimensional data, yet they continue to struggle with one of the most fundamental aspects of biological systems: movement.…

Artificial Intelligence · Computer Science 2025-07-04 Melanie Segado , Felipe Parodi , Jordan K. Matelsky , Michael L. Platt , Eva B. Dyer , Konrad P. Kording

Sleep disorders have emerged as a critical global health issue, highlighting the urgent need for effective and widely accessible intervention technologies. Non-invasive brain stimulation has garnered attention as it enables direct or…

Human-Computer Interaction · Computer Science 2025-12-04 Guisong Liu , Jiansong Zhang , Yinpei Luo , Guoliang Wei , Shuqing Sun , Shiyang Deng , Pengfei Wei , Nanxi Chen

Monolithic neural networks that make use of a single set of weights to learn useful representations for downstream tasks explicitly dismiss the compositional nature of data generation processes. This characteristic exists in data where…

Computer Vision and Pattern Recognition · Computer Science 2023-06-05 Hamed Damirchi , Forest Agostinelli , Pooyan Jamshidi

This paper presents the foundation for a decomposition theory for Boolean networks, a type of discrete dynamical system that has found a wide range of applications in the life sciences, engineering, and physics. Given a Boolean network…

Dynamical Systems · Mathematics 2022-06-10 Claus Kadelka , Reinhard Laubenbacher , David Murrugarra , Alan Veliz-Cuba , Matthew Wheeler

The structure and performance of neural networks are intimately connected, and by use of evolutionary algorithms, neural network structures optimally adapted to a given task can be explored. Guiding such neuroevolution with additional…

Neural and Evolutionary Computing · Computer Science 2019-04-24 Kai Olav Ellefsen , Joost Huizinga , Jim Torresen

It has been hypothesized that some form of "modular" structure in artificial neural networks should be useful for learning, compositionality, and generalization. However, defining and quantifying modularity remains an open problem. We cast…

Machine Learning · Computer Science 2022-06-23 Richard D. Lange , David S. Rolnick , Konrad P. Kording

Biological phenomena differ significantly from physical phenomena. At the heart of this distinction is the fact that biological entities have computational abilities and thus they are inherently difficult to predict. This is the reason why…

Molecular Networks · Quantitative Biology 2009-09-29 Pau Fernandez , Ricard V. Sole

Networked systems are systems of interconnected components, in which the dynamics of each component are influenced by the behavior of neighboring components. Examples of networked systems include biological networks, critical…

Systems and Control · Computer Science 2016-06-01 Andrew Clark , Basel Alomair , Linda Bushnell , Radha Poovendran

Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering. Previous…

Molecular Networks · Quantitative Biology 2012-09-14 Kazuhiro Takemoto

Understanding how movement is controlled by the central nervous system remains a major challenge, with ongoing debate about basic features underlying this control. In this review, we introduce a new conceptual framework for the distribution…

Neurons and Cognition · Quantitative Biology 2022-08-08 François Hug , Simon Avrillon , Jaime Ibáñez , Dario Farina

How can we build generalist robot systems? Scale may not be enough due to the significant multimodality of robotics tasks, lack of easily accessible data and the challenges of deploying on physical hardware. Meanwhile, most deployed robotic…

Robotics · Computer Science 2025-03-11 Murtaza Dalal

We present an approach to study functional segregation and integration in the living brain based on community structure decomposition determined by maximum modularity. We demonstrate this method with a network derived from functional…

Neurons and Cognition · Quantitative Biology 2007-05-23 Adam J. Schwarz , Alessandro Gozzi , Angelo Bifone

Circuits in the brain commonly exhibit modular architectures that factorise complex tasks, resulting in the ability to compositionally generalise and reduce catastrophic forgetting. In contrast, artificial neural networks (ANNs) appear to…

Biological Physics · Physics 2025-12-17 Daoyuan Qian , Qiyao Liang , Ila Fiete

The brain is an intricately structured organ responsible for the rich emergent dynamics that support the complex cognitive functions we enjoy as humans. With around $10^{11}$ neurons and $10^{15}$ synapses, understanding how the human brain…

Neurons and Cognition · Quantitative Biology 2019-02-12 Jason Z. Kim , Danielle S. Bassett

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Hierarchical organization -- the recursive composition of sub-modules -- is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations…

Neural and Evolutionary Computing · Computer Science 2016-09-28 Henok Mengistu , Joost Huizinga , Jean-Baptiste Mouret , Jeff Clune