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Flexible photonics offers the possibility to realize wearable sensors by bridging the advantages of flexible materials and photonic sensing elements. Recently, optical resonators have emerged as a tool to improve its over sensitivity by…

Optics · Physics 2023-12-22 Ningyuan Nie , Yu-Cheng Chen

Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

Quantitative Methods · Quantitative Biology 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…

Optics · Physics 2025-09-18 Zhonghao Li , Zhihan Cai , Chaoyang Gong

We report a theoretical study of clusters of evanescently-coupled 2D whispering-gallery (WG) mode optical micro-cavities (termed "photonic molecules") as chemosensing and biosensing platforms. Photonic molecules (PMs) supporting modes with…

Optics · Physics 2009-11-11 Svetlana V. Boriskina

Biomarker detection is the key to identifying health risks. However, designing sensitive biosensors in a single-use mode for disease diagnosis remains a major challenge. Here, we report sub-monolayer biolasers with remarkable repeatability…

Miniaturized spectrometry system is playing an essential role for materials analysis in the development of in-situ or portable sensing platforms across research and industry. However, there unavoidably exists trade-offs between the…

Our growing ability to tailor healthcare to the needs of individuals has the potential to transform clinical treatment. However, the measurement of multiple biomarkers to inform clinical decisions requires rapid, effective, and affordable…

Biophotonics - and more recently, biointegrated photonics - offer transformative tools for probing cellular processes with unprecedented precision. Among these, whispering gallery mode (WGM) resonators - optical microcavities formed in…

Advances in silicon photonics have resulted in rapidly increasing complexity of integrated circuits. New methods are desirable that allow direct characterization of individual optical components in-situ, without the need for additional…

Bioluminescence detection requires single-photon sensitivity, extremely low detection limits and wide dynamic range. Such performances were traditionally assured by photomultiplier-tubes based systems. However, development of novel…

Instrumentation and Detectors · Physics 2020-08-26 S. Lomazzi , M. Caccia , C. Distasi , M. Dionisi , D. Lim , A. Martemiyanov , L. Nardo , F. A. Ruffinatti , R. Santoro

Droplet-based microfluidic systems are a promising platform forlab-on-a-chip (LoC) applications. These systems can also be used toenhance LoC applications with integrated droplet control information or for data transmission scenarios in the…

Emerging Technologies · Computer Science 2021-01-12 Max Bartunik , Marco Fleischer , Werner Haselmayr , Jens Kirchner

Rapidly developing augmented reality (AR) and 3D holographic display technologies require spatial light modulators (SLM) with high resolution and viewing angle to be able to satisfy increasing customer demands. Currently available SLMs, as…

Plasmonic lasers provide a paradigm-changing approach for the generation of coherent light at the nanoscale. In addition to the usual properties of coherent radiation, the emission of plasmonic lasers can feature high sensitivity to the…

The ability to detect and identify molecules at high sensitivity without the use of labels or capture agents is important for medical diagnostics, threat identification, environmental monitoring, and basic science. Microtoroid optical…

Optics · Physics 2022-10-17 Gwangho Choi , Adley Gin , Judith Su

Lanthanide nanoparticles (LnNPs) feature sharp emission lines together with millisecond emission lifetimes which makes them promising luminescent probes for biosensing and bioimaging. Although LnNPs are gathering a large interest, their…

Exploring and controlling the physical factors that determine the topography of thin liquid dielectric films are of interest in manifold fields of research in physics, applied mathematics, and engineering and have been a key aspect of many…

Optics · Physics 2019-08-27 Shimon Rubin , Brandon Hong , Yeshaiahu Fainman

Fast and programmable transport of liquid droplets on a solid substrate is desirable in microfluidic, thermal, biomedical, and energy devices. Past research has focused on designing substrates with asymmetric structures or gradient…

Sensors that are able to detect and track single unlabelled biomolecules are an important tool both to understand biomolecular dynamics and interactions at nanoscale, and for medical diagnostics operating at their ultimate detection limits.…

Optics · Physics 2016-11-15 N. P. Mauranyapin , L. S. Madsen , M. A. Taylor , M. Waleed , W. P. Bowen

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

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