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Artificial Intelligence (AI), particularly Large Language Models (LLMs), is transforming scientific discovery, enabling rapid knowledge generation and hypothesis formulation. However, a critical challenge is hallucination, where LLMs…

Artificial Intelligence · Computer Science 2025-12-30 Bhanu Prakash Vangala , Sajid Mahmud , Pawan Neupane , Joel Selvaraj , Jianlin Cheng

Large language models (LLMs) are increasingly embedded into recommender systems, where they operate across multiple functional roles such as data augmentation, profiling, and decision making. While prior work emphasizes recommendation…

Human-Computer Interaction · Computer Science 2026-02-10 Donguk Park , Dongwon Lee , Yeon-Chang Lee

Ensuring the safety and reliability of large language models (LLMs) in clinical practice is critical to prevent patient harm. However, LLMs are advancing so rapidly that static benchmarks quickly become obsolete or prone to overfitting,…

Large language models (LLMs) are prone to hallucination stemming from misaligned self-awareness, particularly when processing queries exceeding their knowledge boundaries. While existing mitigation strategies employ uncertainty estimation…

Computation and Language · Computer Science 2025-10-10 Hang Zheng , Hongshen Xu , Yuncong Liu , Lu Chen , Pascale Fung , Kai Yu

The increasing use of Machine Learning (ML) components embedded in autonomous systems -- so-called Learning-Enabled Systems (LESs) -- has resulted in the pressing need to assure their functional safety. As for traditional functional safety,…

Software Engineering · Computer Science 2023-01-16 Yi Dong , Wei Huang , Vibhav Bharti , Victoria Cox , Alec Banks , Sen Wang , Xingyu Zhao , Sven Schewe , Xiaowei Huang

Large Language Models (LLMs) have been widely adopted across various domains, yet their application in the medical field poses unique challenges, particularly concerning the generation of hallucinations. Hallucinations in open-ended long…

Computation and Language · Computer Science 2025-01-22 Zenan Huang , Mingwei Li , Zheng Zhou , Youxin Jiang

Large language models (LLMs) are increasingly being adopted as the cognitive core of embodied agents. However, inherited hallucinations, which stem from failures to ground user instructions in the observed physical environment, can lead to…

Foundation models, e.g., large language models (LLMs), trained on internet-scale data possess zero-shot generalization capabilities that make them a promising technology towards detecting and mitigating out-of-distribution failure modes of…

Robotics · Computer Science 2024-07-12 Rohan Sinha , Amine Elhafsi , Christopher Agia , Matthew Foutter , Edward Schmerling , Marco Pavone

Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin

Recently, overconfidence in large language models (LLMs) has garnered considerable attention due to its fundamental importance in quantifying the trustworthiness of LLM generation. However, existing approaches prompt the \textit{black box…

Computation and Language · Computer Science 2025-04-29 Adil Bahaj , Hamed Rahimi , Mohamed Chetouani , Mounir Ghogho

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Large language models (LLMs) hold substantial promise for clinical decision support. However, their widespread adoption in medicine, particularly in healthcare, is hindered by their propensity to generate false or misleading outputs, known…

Recent studies on the safety alignment of large language models (LLMs) have revealed that existing approaches often operate superficially, leaving models vulnerable to various adversarial attacks. Despite their significance, these studies…

Cryptography and Security · Computer Science 2025-06-02 Jianwei Li , Jung-Eun Kim

A significant proportion of clinical physiologic monitoring alarms are false. This often leads to alarm fatigue in clinical personnel, inevitably compromising patient safety. To combat this issue, researchers have attempted to build Machine…

Machine Learning · Computer Science 2022-06-22 Arnab Dey , Mononito Goswami , Joo Heung Yoon , Gilles Clermont , Michael Pinsky , Marilyn Hravnak , Artur Dubrawski

Current large language models (LLMs) excel in verifiable domains where outputs can be checked before action but prove less reliable for high-stakes strategic decisions with uncertain outcomes. This gap, driven by mutually reinforcing…

Artificial Intelligence · Computer Science 2025-11-12 Alejandro R. Jadad

Large Language Models (LLMs) have demonstrated impressive performance across various tasks, with different models excelling in distinct domains and specific abilities. Effectively combining the predictions of multiple LLMs is crucial for…

Computation and Language · Computer Science 2025-08-01 Jizhou Guo

Artificial intelligence has significantly impacted medical applications, particularly with the advent of Medical Large Vision Language Models (Med-LVLMs), sparking optimism for the future of automated and personalized healthcare. However,…

Large Language Models (LLMs) have demonstrated remarkable capabilities across a variety of tasks in different domains. However, they sometimes generate responses that are logically coherent but factually incorrect or misleading, which is…

Computation and Language · Computer Science 2025-05-23 Fujie Zhang , Peiqi Yu , Biao Yi , Baolei Zhang , Tong Li , Zheli Liu

The recent performance leap of Large Language Models (LLMs) opens up new opportunities across numerous industrial applications and domains. However, erroneous generations, such as false predictions, misinformation, and hallucination made by…

Software Engineering · Computer Science 2025-01-07 Yuheng Huang , Jiayang Song , Zhijie Wang , Shengming Zhao , Huaming Chen , Felix Juefei-Xu , Lei Ma

It is critical that the models pay attention not only to accuracy but also to the certainty of prediction. Uncertain predictions of deep models caused by noisy data raise significant concerns in trustworthy AI areas. To explore and handle…

Machine Learning · Computer Science 2023-03-30 Wei Wei , Jiahuan Zhou , Hongze Li , Ying Wu
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