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Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Jiawei Mao , Yuhan Wang , Lifeng Chen , Can Zhao , Yucheng Tang , Dong Yang , Liangqiong Qu , Daguang Xu , Yuyin Zhou

We propose a novel speculative decoding method tailored for multi-sample reasoning scenarios, such as self-consistency and Best-of-N sampling. Our method exploits the intrinsic consensus of parallel generation paths to synthesize…

Computation and Language · Computer Science 2025-03-10 Yiwei Li , Jiayi Shi , Shaoxiong Feng , Peiwen Yuan , Xinglin Wang , Yueqi Zhang , Ji Zhang , Chuyi Tan , Boyuan Pan , Yao Hu , Kan Li

Denoising diffusion probabilistic models (DDPMs) have achieved high quality image generation without adversarial training, yet they require simulating a Markov chain for many steps to produce a sample. To accelerate sampling, we present…

Machine Learning · Computer Science 2022-10-07 Jiaming Song , Chenlin Meng , Stefano Ermon

Attention mechanisms that confer selective focus on a strict subset of input elements are nearly ubiquitous in language models today. We posit there to be downside to the use of attention: most input information is lost. In support of this…

Computation and Language · Computer Science 2025-03-21 Benjamin L. Badger

Image synthesis approaches, e.g., generative adversarial networks, have been popular as a form of data augmentation in medical image analysis tasks. It is primarily beneficial to overcome the shortage of publicly accessible data and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Shiyi Du , Xiaosong Wang , Yongyi Lu , Yuyin Zhou , Shaoting Zhang , Alan Yuille , Kang Li , Zongwei Zhou

Neural implicit representations have become a popular choice for modeling surfaces due to their adaptability in resolution and support for complex topology. While previous works have achieved impressive reconstruction quality by training on…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Lu Sang , Abhishek Saroha , Maolin Gao , Daniel Cremers

Speculative decoding has emerged as a widely adopted method to accelerate large language model inference without sacrificing the quality of the model outputs. While this technique has facilitated notable speed improvements by enabling…

Computation and Language · Computer Science 2025-02-12 Jacob K Christopher , Brian R Bartoldson , Tal Ben-Nun , Michael Cardei , Bhavya Kailkhura , Ferdinando Fioretto

Inverse protein folding generates valid amino acid sequences that can fold into a desired protein structure, with recent deep-learning advances showing strong potential and competitive performance. However, challenges remain, such as…

Biomolecules · Quantitative Biology 2025-07-29 Peizhen Bai , Filip Miljković , Xianyuan Liu , Leonardo De Maria , Rebecca Croasdale-Wood , Owen Rackham , Haiping Lu

Predictive models trained on imbalanced data tend to produce biased results. This problem is exacerbated when there is not just one output label, but a set of them. This is the case for multilabel learning (MLL) algorithms used to classify…

Machine Learning · Computer Science 2025-01-22 Francisco Charte , Miguel Ángel Dávila , María Dolores Pérez-Godoy , María José del Jesus

In this paper, we present the Directly Denoising Diffusion Model (DDDM): a simple and generic approach for generating realistic images with few-step sampling, while multistep sampling is still preserved for better performance. DDDMs require…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Dan Zhang , Jingjing Wang , Feng Luo

Speculative decoding aims to speed up autoregressive generation of a language model by verifying in parallel the tokens generated by a smaller draft model.In this work, we explore the effectiveness of learning-free, negligible-cost draft…

Machine Learning · Computer Science 2024-11-07 Lawrence Stewart , Matthew Trager , Sujan Kumar Gonugondla , Stefano Soatto

Diffusion Models (DMs) have demonstrated state-of-the-art performance in content generation without requiring adversarial training. These models are trained using a two-step process. First, a forward - diffusion - process gradually adds…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Anwaar Ulhaq , Naveed Akhtar

Diffusion models have shown their effectiveness in generation tasks by well-approximating the underlying probability distribution. However, diffusion models are known to suffer from an amplified inherent bias from the training data in terms…

Machine Learning · Computer Science 2024-10-04 Yujin Choi , Jinseong Park , Hoki Kim , Jaewook Lee , Saerom Park

This study presents a generative optimization framework that builds on a fine-tuned diffusion model and reward-directed sampling to generate high-performance engineering designs. The framework adopts a parametric representation of the…

Machine Learning · Computer Science 2025-08-05 Hadi Keramati , Patrick Kirchen , Mohammed Hannan , Rajeev K. Jaiman

Semantic segmentation is essential in computer vision for various applications, yet traditional approaches face significant challenges, including the high cost of annotation and extensive training for supervised learning. Additionally, due…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yasufumi Kawano , Yoshimitsu Aoki

Masked diffusion models have demonstrated competitive results on various tasks including language generation. However, due to its iterative refinement process, the inference is often bottlenecked by slow and static sampling speed. To…

Machine Learning · Computer Science 2026-03-09 Seo Hyun Kim , Sunwoo Hong , Hojung Jung , Youngrok Park , Se-Young Yun

Diffusion and flow-based models have enabled significant progress in generation tasks across various modalities and have recently found applications in predictive learning. However, unlike typical generation tasks that encourage sample…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yu Zhang , Xingzhuo Guo , Haoran Xu , Jialong Wu , Mingsheng Long

Many segmentation tasks, such as medical image segmentation or future state prediction, are inherently ambiguous, meaning that multiple predictions are equally correct. Current methods typically rely on generative models to capture this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Sebastian Gerard , Josephine Sullivan

Score-based generative models (SGMs) have recently emerged as a promising class of generative models. However, a fundamental limitation is that their inference is very slow due to a need for many (e.g., 2000) iterations of sequential…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Hengyuan Ma , Li Zhang , Xiatian Zhu , Jianfeng Feng

Despite significant progress in the quality of language generated from abstractive summarization models, these models still exhibit the tendency to hallucinate, i.e., output content not supported by the source document. A number of works…

Computation and Language · Computer Science 2022-11-01 Liam van der Poel , Ryan Cotterell , Clara Meister