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Uncertainty quantification (UQ) for large language models (LLMs) is a key building block for safety guardrails of daily LLM applications. Yet, even as LLM agents are increasingly deployed in highly complex tasks, most UQ research still…

Artificial Intelligence · Computer Science 2026-04-21 Changdae Oh , Seongheon Park , To Eun Kim , Jiatong Li , Wendi Li , Samuel Yeh , Xuefeng Du , Hamed Hassani , Paul Bogdan , Dawn Song , Sharon Li

Security analysts are overwhelmed by the volume of alerts and the low context provided by many detection systems. Early-stage investigations typically require manual correlation across multiple log sources, a task that is usually…

Cryptography and Security · Computer Science 2026-04-29 Even Eilertsen , Vasileios Mavroeidis , Gudmund Grov

Quantum ESPRESSO is an integrated suite of computer codes for electronic-structure calculations and materials modeling, based on density-functional theory, plane waves, and pseudopotentials (norm-conserving, ultrasoft, and…

Scientific workflows in computational chemistry and materials science typically involve multiple interdependent steps, such as model preparation, system construction, simulation execution, and data analysis, that researchers have refined…

The integration of Artificial Intelligence (AI) with High-Performance Computing (HPC) is transforming scientific workflows from human-directed pipelines into adaptive systems capable of autonomous decision-making. Large language models…

Large Language Model (LLM) agents, acting on their users' behalf to manipulate and analyze data, are likely to become the dominant workload for data systems in the future. When working with data, agents employ a high-throughput process of…

To accelerate mechanical design and enhance design quality and innovation, we present a Multidisciplinary Design and Optimization (MDO) Agent driven by Large Language Models (LLMs). The agent semi-automates the end-to-end workflow by…

Human-Computer Interaction · Computer Science 2025-11-25 Bingkun Guo , Wentian Li , Xiaojian Liu , Jiaqi Luo , Zibin Yu , Dalong Dong , Shuyou Zhang , Yiming Zhang

The growing complexity of urban mobility systems has made traffic simulation indispensable for evidence-based transportation planning and policy evaluation. However, despite the analytical capabilities of platforms such as the Simulation of…

Human-Computer Interaction · Computer Science 2025-11-11 Minwoo Jeong , Jeeyun Chang , Yoonjin Yoon

In computational biophysics, where molecular data is expanding rapidly and system complexity is increasing exponentially, large language models (LLMs) and agent-based systems are fundamentally reshaping the field. This perspective article…

We present, to our knowledge, the first language-driven agent system capable of executing end-to-end collider phenomenology tasks, instantiated within a decoupled, domain-agnostic architecture for autonomous High-Energy Physics…

High Energy Physics - Phenomenology · Physics 2026-03-17 Shi Qiu , Zeyu Cai , Jiashen Wei , Zeyu Li , Yixuan Yin , Qing-Hong Cao , Chang Liu , Ming-xing Luo , Xing-Bo Yuan , Hua Xing Zhu

Flow physics and more broadly physical phenomena governed by partial differential equations (PDEs), are inherently continuous, high-dimensional and often chaotic in nature. Traditionally, researchers have explored these rich spatiotemporal…

The synthesis of inorganic crystalline materials is essential for modern technology, especially in quantum materials development. However, designing efficient synthesis workflows remains a significant challenge due to the precise…

We introduce ColPackAgent, an agent framework that autonomously runs Monte Carlo simulations of colloidal packing through a Model Context Protocol (MCP) tool server and an agent skill, whether as a standalone agent or inside an existing…

Artificial Intelligence · Computer Science 2026-05-18 Lijie Ding , Changwoo Do

We present Agent S, an open agentic framework that enables autonomous interaction with computers through a Graphical User Interface (GUI), aimed at transforming human-computer interaction by automating complex, multi-step tasks. Agent S…

Artificial Intelligence · Computer Science 2024-10-11 Saaket Agashe , Jiuzhou Han , Shuyu Gan , Jiachen Yang , Ang Li , Xin Eric Wang

The process of scientific discovery relies on an interplay of observations, analysis, and hypothesis generation. Machine learning is increasingly being adopted to address individual aspects of this process. However, it remains an open…

Artificial Intelligence · Computer Science 2026-05-26 Maximilian Nägele , Florian Marquardt

Automating science laboratories enables faster, safer, more accurate, and more reproducible execution of protocols, accelerating the discovery and testing of new materials, drugs, and more. However, setting up and running autonomous labs…

Artificial Intelligence · Computer Science 2026-05-19 Angelos Angelopoulos , James F. Cahoon , Ron Alterovitz

We propose the first multi agent framework for computational fluid dynamics that enables fully automated, end to end simulations directly from natural language queries. The approach integrates four specialized agents Pre processing, Prompt…

Fluid Dynamics · Physics 2025-04-29 Jingsen Feng , Ran Xu , Xu Chu

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan,…

Quantum computing has shown great potential in various quantum chemical applications such as drug discovery, material design, and catalyst optimization. Although significant progress has been made in quantum simulation of simple molecules,…

Quantum Physics · Physics 2023-05-30 Changsu Cao , Jinzhao Sun , Xiao Yuan , Han-Shi Hu , Hung Q. Pham , Dingshun Lv

There is great potential to be explored regarding the use of agent-based modelling and simulation as an alternative paradigm to investigate early-stage cancer interactions with the immune system. It does not suffer from some limitations of…

Multiagent Systems · Computer Science 2015-06-22 Grazziela P Figueredo , Peer-Olaf Siebers , Markus R Owen , Jenna Reps , Uwe Aickelin