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Electrocardiogram (ECG) diagnosis in clinical practice relies on structured reasoning over multiple hierarchical aspects, including cardiac rhythm, conduction properties, waveform morphology, and overall diagnostic impression. However, most…

Artificial Intelligence · Computer Science 2026-05-19 Yang Wu , Xiaoyan Yuan , Hau-San Wong , Xiping Hu

The electrocardiogram (ECG) is a fundamental tool in cardiovascular diagnostics due to its powerful and non-invasive nature. One of the most critical usages is to determine whether more detailed examinations are necessary, with users…

Artificial Intelligence · Computer Science 2025-04-15 Junichiro Takahashi , JingChuan Guan , Masataka Sato , Kaito Baba , Kazuto Haruguchi , Daichi Nagashima , Satoshi Kodera , Norihiko Takeda

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Recent advances in multimodal ECG representation learning center on aligning ECG signals with paired free-text reports. However, suboptimal alignment persists due to the complexity of medical language and the reliance on a full 12-lead…

Machine Learning · Computer Science 2025-02-26 Che Liu , Cheng Ouyang , Zhongwei Wan , Haozhe Wang , Wenjia Bai , Rossella Arcucci

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

The 12-lead electrocardiogram (ECG) is a commonly used tool for detecting cardiac abnormalities such as atrial fibrillation, blocks, and irregular complexes. For the PhysioNet/CinC 2020 Challenge, we built an algorithm using gradient…

Signal Processing · Electrical Eng. & Systems 2020-10-27 Alexander William Wong , Weijie Sun , Sunil Vasu Kalmady , Padma Kaul , Abram Hindle

Electrocardiogram (ECG) delineation plays a crucial role in assisting cardiologists with accurate diagnoses. Prior research studies have explored various methods, including the application of deep learning techniques, to achieve precise…

Machine Learning · Computer Science 2024-06-06 Aram Avetisyan , Nikolas Khachaturov , Ariana Asatryan , Shahane Tigranyan , Yury Markin

This paper systematically investigates the effectiveness of various augmentations for contrastive self-supervised learning of electrocardiogram (ECG) signals and identifies the best parameters. The baseline of our proposed self-supervised…

Signal Processing · Electrical Eng. & Systems 2022-06-16 Sahar Soltanieh , Ali Etemad , Javad Hashemi

Electroencephalography (EEG) foundation models have recently emerged as a promising paradigm for brain-computer interfaces (BCIs), aiming to learn transferable neural representations from large-scale heterogeneous recordings. Despite rapid…

Machine Learning · Computer Science 2026-02-06 Dingkun Liu , Yuheng Chen , Zhu Chen , Zhenyao Cui , Yaozhi Wen , Jiayu An , Jingwei Luo , Dongrui Wu

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to…

ECG heartbeat classification plays a vital role in diagnosis of cardiac arrhythmia. The goal of the Physionet/CinC 2021 challenge was to accurately classify clinical diagnosis based on 12, 6, 4, 3 or 2-lead ECG recordings in order to aid…

Recent advances in large language models (LLMs) have enabled the development of multimodal medical AI. While models such as MedGemini achieve high accuracy on VQA tasks like USMLE MM, their performance on ECG based tasks remains limited,…

Machine Learning · Computer Science 2026-02-12 Junichiro Takahashi , Masataka Sato , Satoshi Kodeta , Norihiko Takeda

The multi-lead electrocardiogram (ECG) stands as a cornerstone of cardiac diagnosis. Recent strides in electrocardiogram self-supervised learning (eSSL) have brightened prospects for enhancing representation learning without relying on…

Machine Learning · Computer Science 2026-01-01 Tan Pan , Yixuan Sun , Chen Jiang , Qiong Gao , Rui Sun , Xingmeng Zhang , Zhenqi Yang , Limei Han , Yixiu Liang , Yuan Cheng , Kaiyu Guo

12-lead ECGs with high sampling frequency are the clinical gold standard for arrhythmia detection, but their short-term, spot-check nature often misses intermittent events. Wearable ECGs enable long-term monitoring but suffer from…

Machine Learning · Computer Science 2025-11-24 Angelina Yan , Matt L. Sampson , Peter Melchior

We introduce a unified benchmarking framework focused on evaluating EEG-based foundation models in clinical applications. The benchmark spans 11 well-defined diagnostic tasks across 14 publicly available EEG datasets, including epilepsy,…

Machine Learning · Computer Science 2025-12-11 Ard Kastrati , Josua Bürki , Jonas Lauer , Cheng Xuan , Raffaele Iaquinto , Roger Wattenhofer

Automated respiratory sound classification supports the diagnosis of pulmonary diseases. However, many deep models still rely on cycle-level analysis and suffer from patient-specific overfitting. We propose PC-MCL (Patient-Consistent…

Audio and Speech Processing · Electrical Eng. & Systems 2026-01-27 Seung Gyu Jeong , Seong-Eun Kim

Specialized foundation models are beginning to emerge in various medical subdomains, but pretraining methodologies and parametric scaling with the size of the pretraining dataset are rarely assessed systematically and in a like-for-like…

Signal Processing · Electrical Eng. & Systems 2026-05-13 M A Al-Masud , Nils Strodthoff

Deep learning has emerged as the preferred modeling approach for automatic ECG analysis. In this study, we investigate three elements aimed at improving the quantitative accuracy of such systems. These components consistently enhance…

Signal Processing · Electrical Eng. & Systems 2023-08-30 Temesgen Mehari , Nils Strodthoff

Electrocardiogram (ECG) analysis is foundational for cardiovascular disease diagnosis, yet the performance of deep learning models is often constrained by limited access to annotated data. Self-supervised contrastive learning has emerged as…

Machine Learning · Computer Science 2025-08-22 Yi Yuan , Joseph Van Duyn , Runze Yan , Zhuoyi Huang , Sulaiman Vesal , Sergey Plis , Xiao Hu , Gloria Hyunjung Kwak , Ran Xiao , Alex Fedorov

Automated classification of electrocardiogram (ECG) signals is a useful tool for diagnosing and monitoring cardiovascular diseases. This study compares three traditional machine learning algorithms (Decision Tree Classifier, Random Forest…

Machine Learning · Computer Science 2026-04-20 Saloni Garg , Ukant Jadia , Amit Sagtani , Kamal Kant Hiran