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In science and medicine, model interpretations may be reported as discoveries of natural phenomena or used to guide patient treatments. In such high-stakes tasks, false discoveries may lead investigators astray. These applications would…

Machine Learning · Statistics 2020-08-18 Collin Burns , Jesse Thomason , Wesley Tansey

Feature selection on incomplete datasets is an exceptionally challenging task. Existing methods address this challenge by first employing imputation methods to complete the incomplete data and then conducting feature selection based on the…

Machine Learning · Computer Science 2024-08-14 Cong Guo

This paper claims that machine learning models deployed in high stakes domains such as medicine must be interpretable, shareable, reproducible and accountable. We argue that these principles should form the foundational design criteria for…

Machine Learning · Computer Science 2025-08-25 Ayyüce Begüm Bektaş , Mithat Gönen

Consensus clustering has been widely used in bioinformatics and other applications to improve the accuracy, stability and reliability of clustering results. This approach ensembles cluster co-occurrences from multiple clustering runs on…

Machine Learning · Statistics 2023-01-11 Luqin Gan , Genevera I. Allen

Accelerating the discovery and manufacturing of advanced materials with specific properties is a critical yet formidable challenge due to vast search space, high costs of experiments, and time-intensive nature of material characterization.…

Machine Learning · Computer Science 2025-03-28 Ahmed Shoyeb Raihan , Zhichao Liu , Tanveer Hossain Bhuiyan , Imtiaz Ahmed

In recent times, machine learning (ML) and artificial intelligence (AI) based systems have evolved and scaled across different industries such as finance, retail, insurance, energy utilities, etc. Among other things, they have been used to…

Machine Learning · Computer Science 2019-10-02 Akshay Arora , Arun Nethi , Priyanka Kharat , Vency Verghese , Grant Jenkins , Steve Miff , Vikas Chowdhry , Xiao Wang

In health related machine learning applications, the training data often corresponds to a non-representative sample from the target populations where the learners will be deployed. In anticausal prediction tasks, selection biases often make…

Machine Learning · Statistics 2020-11-10 Elias Chaibub Neto , Phil Snyder , Solveig K Sieberts , Larsson Omberg

Evaluating classifications is crucial in statistics and machine learning, as it influences decision-making across various fields, such as patient prognosis and therapy in critical conditions. The Matthews correlation coefficient (MCC) is…

Methodology · Statistics 2024-06-18 Yuki Itaya , Jun Tamura , Kenichi Hayashi , Kouji Yamamoto

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

Artificial Intelligence · Computer Science 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Continuous monitoring of trained ML models to determine when their predictions should and should not be trusted is essential for their safe deployment. Such a framework ought to be high-performing, explainable, post-hoc and actionable. We…

Machine Learning · Computer Science 2023-07-14 Nandita Bhaskhar , Daniel L. Rubin , Christopher Lee-Messer

Measuring the confidence of AI models is critical for safely deploying AI in real-world industrial systems. One important application of confidence measurement is information extraction from scanned documents. However, there exists no…

Information Retrieval · Computer Science 2022-10-11 Bao-Sinh Nguyen , Quang-Bach Tran , Tuan-Anh Nguyen Dang , Duc Nguyen , Hung Le

The 3D deep learning community has seen significant strides in pointcloud processing over the last few years. However, the datasets on which deep models have been trained have largely remained the same. Most datasets comprise clean,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-19 Saeid Asgari Taghanaki , Jieliang Luo , Ran Zhang , Ye Wang , Pradeep Kumar Jayaraman , Krishna Murthy Jatavallabhula

Estimating the effects of continuous-valued interventions from observational data is a critically important task for climate science, healthcare, and economics. Recent work focuses on designing neural network architectures and…

Machine Learning · Computer Science 2022-10-13 Andrew Jesson , Alyson Douglas , Peter Manshausen , Maëlys Solal , Nicolai Meinshausen , Philip Stier , Yarin Gal , Uri Shalit

Clustering is a fundamental learning task widely used as a first step in data analysis. For example, biologists use cluster assignments to analyze genome sequences, medical records, or images. Since downstream analysis is typically…

Machine Learning · Computer Science 2024-06-11 Jonathan Svirsky , Ofir Lindenbaum

As a knowledge discovery task over heterogeneous data sources, current Multimodal Affective Computing (MAC) heavily rely on the completeness of multiple modalities to accurately understand human's affective state. However, in real-world…

Artificial Intelligence · Computer Science 2026-02-03 Ronghao Lin , Honghao Lu , Ruixing Wu , Aolin Xiong , Qinggong Chu , Qiaolin He , Sijie Mai , Haifeng Hu

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Nonlinear causal discovery from observational data imposes strict identifiability assumptions on the formulation of structural equations utilized in the data generating process. The evaluation of structure learning methods under assumption…

Machine Learning · Statistics 2024-12-17 Georg Velev , Stefan Lessmann

Understanding causal heterogeneity is essential for scientific discovery in domains such as biology and medicine. However, existing methods lack causal awareness, with insufficient modeling of heterogeneity, confounding, and observational…

Machine Learning · Computer Science 2025-10-29 Wenrui Li , Qinghao Zhang , Xiaowo Wang

Feature selection techniques have been used as the workhorse in biomarker discovery applications for a long time. Surprisingly, the stability of feature selection with respect to sampling variations has long been under-considered. It is…

Computational Engineering, Finance, and Science · Computer Science 2010-01-07 Zengyou He , Weichuan Yu

Challenges have become the state-of-the-art approach to benchmark image analysis algorithms in a comparative manner. While the validation on identical data sets was a great step forward, results analysis is often restricted to pure ranking…