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The increasing volumes of data produced by high-throughput instruments coupled with advanced computational infrastructures for scientific computing have enabled what is often called a {\em Fourth Paradigm} for scientific research based on…

Transformer-based language models have become the standard approach to solving natural language processing tasks. However, industry adoption usually requires the maximum throughput to comply with certain latency constraints that prevents…

Computation and Language · Computer Science 2022-12-08 Haihao Shen , Ofir Zafrir , Bo Dong , Hengyu Meng , Xinyu Ye , Zhe Wang , Yi Ding , Hanwen Chang , Guy Boudoukh , Moshe Wasserblat

Machine- and deep-learning approaches for biological sequences depend critically on transforming raw DNA, RNA, and protein FASTA files into informative numerical representations. However, this process is often fragmented across multiple…

Genomics · Quantitative Biology 2025-12-01 Hamid Ismail , Marwan Bikdash

\textbf{Background:} Regulatory frameworks for AI in healthcare, including the EU AI Act and FDA guidance on AI/ML-based medical devices, require clinical decision support to demonstrate not only accuracy but auditability. Existing formal…

Artificial Intelligence · Computer Science 2026-04-24 Michael Bouzinier , Sergey Trifonov , Michael Chumack , Eugenia Lvova , Dmitry Etin

We provide a novel notion of what it means to be interpretable, looking past the usual association with human understanding. Our key insight is that interpretability is not an absolute concept and so we define it relative to a target model,…

Artificial Intelligence · Computer Science 2018-10-30 Amit Dhurandhar , Vijay Iyengar , Ronny Luss , Karthikeyan Shanmugam

Fine-grained entity typing (FET), which assigns entities in text with context-sensitive, fine-grained semantic types, is a basic but important task for knowledge extraction from unstructured text. FET has been studied extensively in natural…

Computation and Language · Computer Science 2024-06-12 Tanay Komarlu , Minhao Jiang , Xuan Wang , Jiawei Han

We introduce $\mathsf{PREM}$ (Private Relative Error Multiplicative weight update), a new framework for generating synthetic data that achieves a relative error guarantee for statistical queries under $(\varepsilon, \delta)$ differential…

Machine Learning · Computer Science 2025-02-21 Badih Ghazi , Cristóbal Guzmán , Pritish Kamath , Alexander Knop , Ravi Kumar , Pasin Manurangsi , Sushant Sachdeva

Taxonomies have been widely used in various machine learning and text mining systems to organize knowledge and facilitate downstream tasks. One critical challenge is that, as data and business scope grow in real applications, existing…

Computation and Language · Computer Science 2021-04-13 Xiangchen Song , Jiaming Shen , Jieyu Zhang , Jiawei Han

The increasing complexity and volume of data generated by high-throughput computational materials science require robust tools to ensure their accessibility, reproducibility, and reuse. In particular, integrating the FAIR Guiding Principles…

Materials Science · Physics 2025-10-28 Lucrezia Berghenti , Elisa Damiani , Margherita Marsili , Maria Clelia Righi

The integration of advanced technologies, such as Artificial Intelligence (AI), into manufacturing processes is attracting significant attention, paving the way for the development of intelligent systems that enhance efficiency and…

Neural and Evolutionary Computing · Computer Science 2025-12-09 Mohammadhossein Ghahramani , Yan Qiao , NaiQi Wu , Mengchu Zhou

Heterogeneous, interconnected, systems-level, molecular data have become increasingly available and key in precision medicine. We need to utilize them to better stratify patients into risk groups, discover new biomarkers and targets,…

Other Quantitative Biology · Quantitative Biology 2024-05-17 Natasa Przulj , Noel Malod-Dognin

The reproducibility of computational pipelines is an expectation in biomedical science, particularly in critical domains like human health. In this context, reporting next generation genome sequencing methods used in precision medicine…

Computational Engineering, Finance, and Science · Computer Science 2024-12-11 Meznah Aloqalaa , Stian Soiland-Reyes , Carole Goble

Motivation: Phenotype concept recognition (CR) is a fundamental task in biomedical text mining. However, existing methods either require ontology-specific training, making them struggle to generalize across diverse text styles and evolving…

Computation and Language · Computer Science 2026-04-06 Yicheng Tao , Yuanhao Huang , Yiqun Wang , Xin Luo , Jie Liu

Federated learning (FL) is a promising approach for enhancing data privacy preservation, particularly for authentication systems. However, limited round communications, scarce representation, and scalability pose significant challenges to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Hansol Kim , Youngjun Kwak , Minyoung Jung , Jinho Shin , Youngsung Kim , Changick Kim

Technology advances in areas such as sensors, IoT, and robotics, enable new collaborative applications (e.g., autonomous devices). A primary requirement for such collaborations is to have a secure system which enables information sharing…

Cryptography and Security · Computer Science 2020-11-04 Amani Abu Jabal , Elisa Bertino , Jorge Lobo , Dinesh Verma , Seraphin Calo , Alessandra Russo

The adoption of automated, data-driven decision making in an ever expanding range of applications has raised concerns about its potential unfairness towards certain social groups. In this context, a number of recent studies have focused on…

The connect-fill-run workflow paradigm, widely adopted in mature software engineering, accelerates collaborative development. However, computational chemistry, computational materials science, and computational biology face persistent…

Chemical Physics · Physics 2025-08-12 Jianan Wang , Wenbo Guo , Xin Yue , Minjie Xu , Yueqiang Zheng , Jingxiang Dong , Jiarui Hu , Jian Xia , Chuixiong Wu

Protein structure prediction and folding are fundamental to understanding biology, with recent deep learning advances reshaping the field. Diffusion-based generative models have revolutionized protein design, enabling the creation of novel…

Machine Learning · Computer Science 2025-10-01 Yogesh Verma , Markus Heinonen , Vikas Garg

Recently, Machine Learning (ML) methods are built-in as an important component in many smart agriculture platforms. In this paper, we explore the new combination of advanced ML methods for creating a smart agriculture platform where farmers…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Aswath Muthuselvam , S. Sowdeshwar , M. Saravanan , Satheesh K. Perepu